3490 (A > G)

General info

Chr
chrM
Start
3490
End
3490
Ref
A
Alt
G
Mitimpact ID
MI.11141
Gene symbol
MT-ND1
Oxphos complex
I
Ensembl gene ID
Ensembl protein ID
Ensembl transcript ID
Uniprot name
Uniprot ID
Ncbi gene ID
Ncbi protein ID
Gene position
184
AA position
62
AA ref
K
AA alt
E
Codon substitution
Aaa/Gaa
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Conservation

PhyloP 100v
-3
PhastCons 100v
0

Pathogenicity predictors

PolyPhen2
Benign
PolyPhen2 score
0.18
SIFT
Neutral
SIFT score
1
FatHmm
Neutral
FatHmm score
-0.79
FatHMMW
Neutral
FatHMMW score
2.77
PROVEAN
Neutral
PROVEAN score
-1.36
Mutation Assessor
Medium impact
Mutation Assessor score
1.95
EFIN SP
Neutral
EFIN SP score
0.84
EFIN HD
Neutral
EFIN HD score
0.7
VEST p-value
0.26
VEST FDR
0.45
PANTHER
Neutral
PANTHER score
0.24
PhD-SNP
Disease
PhD-SNP score
0.64
MutationTaster
Polymorphism
MutationTaster score
1
CADD
Deleterious
CADD score
3.92
CADD phred
23.5
SNAP
Neutral
SNAP score
0.43
MitoClass 1
Neutral
SNPDryad score
0.74

Pathogenicity meta-predictors

CAROL
Neutral
CAROL score
0.18
Condel
Deleterious
Condel score
0.91
COVEC WMV
Neutral
COVEC WMV score
-3
Meta SNP
Disease
Meta SNP score
0.5
Meta SNP RI
0
MtoolBox
Neutral
MtoolBox DS
0.27
APOGEE consensus
N
APOGEE mean p
0.25
DEOGEN score
0.02

Cancer-specific predictors

PolyPhen2 transf
Medium impact
PolyPhen2 transf score
-0.13
SIFT transf
High impact
SIFT transf score
1.96
MutationAssessor transf
Medium impact
MutationAssessor transf score
0.52
CHASM p-value
0.42
CHASM FDR
0.8

Residue interaction

EV Mutation
Site A-B InterP
Site A-B IntraP
ΔΔG intra
ΔΔG intra interface
ΔΔG inter

Frequency & Phenotype DBs

ClinVar June2018 ClinSig
.
ClinVar June2018 ClnDBN
.
ClinVar June2018 ClnAllele ID
.
ClinVar June2018 ClnDSDB
.
Mitomap Allele
.
Mitomap Phenotype
.
Mitomap Homoplasmy
.
Mitomap Heteroplasmy
.
Mitomap Status
.
Mitomap NRef
.
COSMIC 87
.
Classification Clinvar
.
Classification Mitomap
.
Classification global
.
dbSNP 151 ID

Pathogenic variants, CPD

CPD candidate
.
CPD frequency
.
CPD AA ref
.
CPD AA alt
.
CPD aln pos
.
CPD RefSeq Protein ID
.
CPD Species name
.
CPD Ncbi Taxon ID
.

3490 (A > C)

General info

Chr
chrM
Start
3490
End
3490
Ref
A
Alt
C
Mitimpact ID
MI.11142
Gene symbol
MT-ND1
Oxphos complex
I
Ensembl gene ID
Ensembl protein ID
Ensembl transcript ID
Uniprot name
Uniprot ID
Ncbi gene ID
Ncbi protein ID
Gene position
184
AA position
62
AA ref
K
AA alt
Q
Codon substitution
Aaa/Caa
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Conservation

PhyloP 100v
-3
PhastCons 100v
0

Pathogenicity predictors

PolyPhen2
Benign
PolyPhen2 score
0.02
SIFT
Neutral
SIFT score
0.59
FatHmm
Neutral
FatHmm score
-0.67
FatHMMW
Neutral
FatHMMW score
2.76
PROVEAN
Neutral
PROVEAN score
-0.29
Mutation Assessor
Low impact
Mutation Assessor score
1.32
EFIN SP
Neutral
EFIN SP score
0.82
EFIN HD
Neutral
EFIN HD score
0.97
VEST p-value
0.39
VEST FDR
0.5
PANTHER
Neutral
PANTHER score
0.27
PhD-SNP
Neutral
PhD-SNP score
0.33
MutationTaster
Polymorphism
MutationTaster score
1
CADD
Deleterious
CADD score
2.2
CADD phred
17.49
SNAP
Neutral
SNAP score
0.25
MitoClass 1
Neutral
SNPDryad score
0.59

Pathogenicity meta-predictors

CAROL
Neutral
CAROL score
0.38
Condel
Deleterious
Condel score
0.79
COVEC WMV
Neutral
COVEC WMV score
-6
Meta SNP
Neutral
Meta SNP score
0.44
Meta SNP RI
1
MtoolBox
Neutral
MtoolBox DS
0.16
APOGEE consensus
N
APOGEE mean p
0.36
DEOGEN score
0.01

Cancer-specific predictors

PolyPhen2 transf
Medium impact
PolyPhen2 transf score
0.84
SIFT transf
Medium impact
SIFT transf score
0.36
MutationAssessor transf
Medium impact
MutationAssessor transf score
-0.04
CHASM p-value
0.36
CHASM FDR
0.8

Residue interaction

EV Mutation
Site A-B InterP
Site A-B IntraP
ΔΔG intra
ΔΔG intra interface
ΔΔG inter

Frequency & Phenotype DBs

ClinVar June2018 ClinSig
.
ClinVar June2018 ClnDBN
.
ClinVar June2018 ClnAllele ID
.
ClinVar June2018 ClnDSDB
.
Mitomap Allele
.
Mitomap Phenotype
.
Mitomap Homoplasmy
.
Mitomap Heteroplasmy
.
Mitomap Status
.
Mitomap NRef
.
COSMIC 87
.
Classification Clinvar
.
Classification Mitomap
.
Classification global
.
dbSNP 151 ID

Pathogenic variants, CPD

CPD candidate
.
CPD frequency
.
CPD AA ref
.
CPD AA alt
.
CPD aln pos
.
CPD RefSeq Protein ID
.
CPD Species name
.
CPD Ncbi Taxon ID
.

3491 (A > C)

General info

Chr
chrM
Start
3491
End
3491
Ref
A
Alt
C
Mitimpact ID
MI.11143
Gene symbol
MT-ND1
Oxphos complex
I
Ensembl gene ID
Ensembl protein ID
Ensembl transcript ID
Uniprot name
Uniprot ID
Ncbi gene ID
Ncbi protein ID
Gene position
185
AA position
62
AA ref
K
AA alt
T
Codon substitution
aAa/aCa
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Conservation

PhyloP 100v
0.22
PhastCons 100v
0

Pathogenicity predictors

PolyPhen2
Benign
PolyPhen2 score
0.41
SIFT
Neutral
SIFT score
0.59
FatHmm
Neutral
FatHmm score
1.17
FatHMMW
Neutral
FatHMMW score
2.81
PROVEAN
Deleterious
PROVEAN score
-2.5
Mutation Assessor
Neutral impact
Mutation Assessor score
0.55
EFIN SP
Neutral
EFIN SP score
0.69
EFIN HD
Neutral
EFIN HD score
0.66
VEST p-value
0.14
VEST FDR
0.4
PANTHER
Neutral
PANTHER score
0.16
PhD-SNP
Neutral
PhD-SNP score
0.37
MutationTaster
Polymorphism
MutationTaster score
1
CADD
Deleterious
CADD score
3.51
CADD phred
23.1
SNAP
Neutral
SNAP score
0.38
MitoClass 1
Neutral
SNPDryad score
0.75

Pathogenicity meta-predictors

CAROL
Neutral
CAROL score
0.37
Condel
Deleterious
Condel score
0.59
COVEC WMV
Neutral
COVEC WMV score
-6
Meta SNP
Neutral
Meta SNP score
0.43
Meta SNP RI
1
MtoolBox
Neutral
MtoolBox DS
0.37
APOGEE consensus
N
APOGEE mean p
0.3
DEOGEN score
0.07

Cancer-specific predictors

PolyPhen2 transf
Medium impact
PolyPhen2 transf score
-0.6
SIFT transf
Medium impact
SIFT transf score
0.36
MutationAssessor transf
Medium impact
MutationAssessor transf score
-0.71
CHASM p-value
0.2
CHASM FDR
0.8

Residue interaction

EV Mutation
Site A-B InterP
Site A-B IntraP
ΔΔG intra
ΔΔG intra interface
ΔΔG inter

Frequency & Phenotype DBs

ClinVar June2018 ClinSig
.
ClinVar June2018 ClnDBN
.
ClinVar June2018 ClnAllele ID
.
ClinVar June2018 ClnDSDB
.
Mitomap Allele
.
Mitomap Phenotype
.
Mitomap Homoplasmy
.
Mitomap Heteroplasmy
.
Mitomap Status
.
Mitomap NRef
.
COSMIC 87
.
Classification Clinvar
.
Classification Mitomap
.
Classification global
.
dbSNP 151 ID

Pathogenic variants, CPD

CPD candidate
.
CPD frequency
.
CPD AA ref
.
CPD AA alt
.
CPD aln pos
.
CPD RefSeq Protein ID
.
CPD Species name
.
CPD Ncbi Taxon ID
.

3491 (A > T)

General info

Chr
chrM
Start
3491
End
3491
Ref
A
Alt
T
Mitimpact ID
MI.11144
Gene symbol
MT-ND1
Oxphos complex
I
Ensembl gene ID
Ensembl protein ID
Ensembl transcript ID
Uniprot name
Uniprot ID
Ncbi gene ID
Ncbi protein ID
Gene position
185
AA position
62
AA ref
K
AA alt
M
Codon substitution
aAa/aTa
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Conservation

PhyloP 100v
0.22
PhastCons 100v
0

Pathogenicity predictors

PolyPhen2
Possibly damaging
PolyPhen2 score
0.58
SIFT
Neutral
SIFT score
0.12
FatHmm
Neutral
FatHmm score
-0.08
FatHMMW
Neutral
FatHMMW score
2.74
PROVEAN
Neutral
PROVEAN score
-2.33
Mutation Assessor
Low impact
Mutation Assessor score
1.05
EFIN SP
Neutral
EFIN SP score
0.71
EFIN HD
Neutral
EFIN HD score
0.61
VEST p-value
0.12
VEST FDR
0.4
PANTHER
Neutral
PANTHER score
0.3
PhD-SNP
Neutral
PhD-SNP score
0.45
MutationTaster
Polymorphism
MutationTaster score
1
CADD
Deleterious
CADD score
3.74
CADD phred
23.3
SNAP
Neutral
SNAP score
0.28
MitoClass 1
Neutral
SNPDryad score
0.78

Pathogenicity meta-predictors

CAROL
Neutral
CAROL score
0.88
Condel
Neutral
Condel score
0.27
COVEC WMV
Neutral
COVEC WMV score
-3
Meta SNP
Neutral
Meta SNP score
0.49
Meta SNP RI
0
MtoolBox
Deleterious
MtoolBox DS
0.5
APOGEE consensus
N
APOGEE mean p
0.41
DEOGEN score
0.07

Cancer-specific predictors

PolyPhen2 transf
Medium impact
PolyPhen2 transf score
-0.88
SIFT transf
Medium impact
SIFT transf score
-0.21
MutationAssessor transf
Medium impact
MutationAssessor transf score
-0.27
CHASM p-value
0.19
CHASM FDR
0.8

Residue interaction

EV Mutation
Site A-B InterP
Site A-B IntraP
ΔΔG intra
ΔΔG intra interface
ΔΔG inter

Frequency & Phenotype DBs

ClinVar June2018 ClinSig
.
ClinVar June2018 ClnDBN
.
ClinVar June2018 ClnAllele ID
.
ClinVar June2018 ClnDSDB
.
Mitomap Allele
.
Mitomap Phenotype
.
Mitomap Homoplasmy
.
Mitomap Heteroplasmy
.
Mitomap Status
.
Mitomap NRef
.
COSMIC 87
.
Classification Clinvar
.
Classification Mitomap
.
Classification global
.
dbSNP 151 ID

Pathogenic variants, CPD

CPD candidate
.
CPD frequency
.
CPD AA ref
.
CPD AA alt
.
CPD aln pos
.
CPD RefSeq Protein ID
.
CPD Species name
.
CPD Ncbi Taxon ID
.

General info

Chr
chrM
Start
3492
End
3492
Ref
A
Alt
T
Mitimpact ID
MI.11145
Gene symbol
MT-ND1
Oxphos complex
I
Ensembl gene ID
Ensembl protein ID
Ensembl transcript ID
Uniprot name
Uniprot ID
Ncbi gene ID
Ncbi protein ID
Gene position
186
AA position
62
AA ref
K
AA alt
N
Codon substitution
aaA/aaT
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Conservation

PhyloP 100v
0.45
PhastCons 100v
0

Pathogenicity predictors

PolyPhen2
Benign
PolyPhen2 score
0.26
SIFT
Neutral
SIFT score
0.51
FatHmm
Neutral
FatHmm score
-1.09
FatHMMW
Neutral
FatHMMW score
2.75
PROVEAN
Neutral
PROVEAN score
-1.59
Mutation Assessor
Low impact
Mutation Assessor score
1.29
EFIN SP
Neutral
EFIN SP score
0.68
EFIN HD
Neutral
EFIN HD score
0.67
VEST p-value
0.5
VEST FDR
0.6
PANTHER
Neutral
PANTHER score
0.3
PhD-SNP
Disease
PhD-SNP score
0.52
MutationTaster
Polymorphism
MutationTaster score
1
CADD
Deleterious
CADD score
3.82
CADD phred
23.4
SNAP
Neutral
SNAP score
0.28
MitoClass 1
Neutral
SNPDryad score
0.59

Pathogenicity meta-predictors

CAROL
Neutral
CAROL score
0.39
Condel
Deleterious
Condel score
0.63
COVEC WMV
Neutral
COVEC WMV score
-6
Meta SNP
Disease
Meta SNP score
0.5
Meta SNP RI
0
MtoolBox
Neutral
MtoolBox DS
0.38
APOGEE consensus
N
APOGEE mean p
0.38
DEOGEN score
0.02

Cancer-specific predictors

PolyPhen2 transf
Medium impact
PolyPhen2 transf score
-0.32
SIFT transf
Medium impact
SIFT transf score
0.29
MutationAssessor transf
Medium impact
MutationAssessor transf score
-0.06
CHASM p-value
0.34
CHASM FDR
0.8

Residue interaction

EV Mutation
Site A-B InterP
Site A-B IntraP
ΔΔG intra
ΔΔG intra interface
ΔΔG inter

Frequency & Phenotype DBs

ClinVar June2018 ClinSig
.
ClinVar June2018 ClnDBN
.
ClinVar June2018 ClnAllele ID
.
ClinVar June2018 ClnDSDB
.
Mitomap Allele
.
Mitomap Phenotype
.
Mitomap Homoplasmy
.
Mitomap Heteroplasmy
.
Mitomap Status
.
Mitomap NRef
.
COSMIC 87
.
Classification Clinvar
.
Classification Mitomap
.
Classification global
.
dbSNP 151 ID

Pathogenic variants, CPD

CPD candidate
.
CPD frequency
.
CPD AA ref
.
CPD AA alt
.
CPD aln pos
.
CPD RefSeq Protein ID
.
CPD Species name
.
CPD Ncbi Taxon ID
.

General info

Chr
chrM
Start
3492
End
3492
Ref
A
Alt
C
Mitimpact ID
MI.11146
Gene symbol
MT-ND1
Oxphos complex
I
Ensembl gene ID
Ensembl protein ID
Ensembl transcript ID
Uniprot name
Uniprot ID
Ncbi gene ID
Ncbi protein ID
Gene position
186
AA position
62
AA ref
K
AA alt
N
Codon substitution
aaA/aaC
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Conservation

PhyloP 100v
0.45
PhastCons 100v
0

Pathogenicity predictors

PolyPhen2
Benign
PolyPhen2 score
0.26
SIFT
Neutral
SIFT score
0.51
FatHmm
Neutral
FatHmm score
-1.09
FatHMMW
Neutral
FatHMMW score
2.75
PROVEAN
Neutral
PROVEAN score
-1.59
Mutation Assessor
Low impact
Mutation Assessor score
1.29
EFIN SP
Neutral
EFIN SP score
0.68
EFIN HD
Neutral
EFIN HD score
0.67
VEST p-value
0.5
VEST FDR
0.6
PANTHER
Neutral
PANTHER score
0.3
PhD-SNP
Disease
PhD-SNP score
0.52
MutationTaster
Polymorphism
MutationTaster score
1
CADD
Deleterious
CADD score
3.75
CADD phred
23.3
SNAP
Neutral
SNAP score
0.28
MitoClass 1
Neutral
SNPDryad score
0.59

Pathogenicity meta-predictors

CAROL
Neutral
CAROL score
0.39
Condel
Deleterious
Condel score
0.63
COVEC WMV
Neutral
COVEC WMV score
-6
Meta SNP
Disease
Meta SNP score
0.5
Meta SNP RI
0
MtoolBox
Neutral
MtoolBox DS
0.38
APOGEE consensus
N
APOGEE mean p
0.38
DEOGEN score
0.02

Cancer-specific predictors

PolyPhen2 transf
Medium impact
PolyPhen2 transf score
-0.32
SIFT transf
Medium impact
SIFT transf score
0.29
MutationAssessor transf
Medium impact
MutationAssessor transf score
-0.06
CHASM p-value
0.34
CHASM FDR
0.8

Residue interaction

EV Mutation
Site A-B InterP
Site A-B IntraP
ΔΔG intra
ΔΔG intra interface
ΔΔG inter

Frequency & Phenotype DBs

ClinVar June2018 ClinSig
.
ClinVar June2018 ClnDBN
.
ClinVar June2018 ClnAllele ID
.
ClinVar June2018 ClnDSDB
.
Mitomap Allele
.
Mitomap Phenotype
.
Mitomap Homoplasmy
.
Mitomap Heteroplasmy
.
Mitomap Status
.
Mitomap NRef
.
COSMIC 87
.
Classification Clinvar
N
Classification Mitomap
.
Classification global
N
dbSNP 151 ID

Pathogenic variants, CPD

CPD candidate
.
CPD frequency
.
CPD AA ref
.
CPD AA alt
.
CPD aln pos
.
CPD RefSeq Protein ID
.
CPD Species name
.
CPD Ncbi Taxon ID
.
~ 3490 (A/G) 3490 (A/C) 3491 (A/C) 3491 (A/T) 3492 (A/T) 3492 (A/C)
~ 3490 (Aaa/Gaa) 3490 (Aaa/Caa) 3491 (aAa/aCa) 3491 (aAa/aTa) 3492 (aaA/aaT) 3492 (aaA/aaC)
Chr chrM chrM chrM chrM chrM chrM
Start 3490 3490 3491 3491 3492 3492
End 3490 3490 3491 3491 3492 3492
Ref A A A A A A
Alt G C C T T C
MitImpact id MI.11141 MI.11142 MI.11143 MI.11144 MI.11145 MI.11146
Gene symbol MT-ND1 MT-ND1 MT-ND1 MT-ND1 MT-ND1 MT-ND1
OXPHOS complex I I I I I I
Ensembl gene id ENSG00000198888 ENSG00000198888 ENSG00000198888 ENSG00000198888 ENSG00000198888 ENSG00000198888
Ensembl protein id ENSP00000354687 ENSP00000354687 ENSP00000354687 ENSP00000354687 ENSP00000354687 ENSP00000354687
Ensembl transcript id ENST00000361390 ENST00000361390 ENST00000361390 ENST00000361390 ENST00000361390 ENST00000361390
Uniprot name NU1M_HUMAN NU1M_HUMAN NU1M_HUMAN NU1M_HUMAN NU1M_HUMAN NU1M_HUMAN
Uniprot id P03886 P03886 P03886 P03886 P03886 P03886
Ncbi gene id 4535 4535 4535 4535 4535 4535
Ncbi protein id YP_003024026.1 YP_003024026.1 YP_003024026.1 YP_003024026.1 YP_003024026.1 YP_003024026.1
Gene position 184 184 185 185 186 186
AA position 62 62 62 62 62 62
AA ref K K K K K K
AA alt E Q T M N N
Codon substitution Aaa/Gaa Aaa/Caa aAa/aCa aAa/aTa aaA/aaT aaA/aaC
PhyloP 100V -3 -3 0.22 0.22 0.45 0.45
PhastCons 100V 0 0 0 0 0 0
PolyPhen2 benign benign benign possibly_damaging benign benign
PolyPhen2 score 0.18 0.02 0.41 0.58 0.26 0.26
SIFT neutral neutral neutral neutral neutral neutral
SIFT score 1 0.59 0.59 0.12 0.51 0.51
FatHmm neutral neutral neutral neutral neutral neutral
FatHmm score -0.79 -0.67 1.17 -0.08 -1.09 -1.09
FatHmmW neutral neutral neutral neutral neutral neutral
FatHmmW score 2.77 2.76 2.81 2.74 2.75 2.75
PROVEAN neutral neutral deleterious neutral neutral neutral
PROVEAN score -1.36 -0.29 -2.5 -2.33 -1.59 -1.59
MutationAssessor medium impact low impact neutral impact low impact low impact low impact
MutationAssessor score 1.95 1.32 0.55 1.05 1.29 1.29
EFIN SP neutral neutral neutral neutral neutral neutral
EFIN SP score 0.84 0.82 0.69 0.71 0.68 0.68
EFIN HD neutral neutral neutral neutral neutral neutral
EFIN HD score 0.7 0.97 0.66 0.61 0.67 0.67
CADD deleterious deleterious deleterious deleterious deleterious deleterious
CADD score 3.92 2.2 3.51 3.74 3.82 3.75
CADD phred 23.5 17.49 23.1 23.3 23.4 23.3
VEST pvalue 0.26 0.39 0.14 0.12 0.5 0.5
VEST FDR 0.45 0.5 0.4 0.4 0.6 0.6
PANTHER neutral neutral neutral neutral neutral neutral
PANTHER score 0.24 0.27 0.16 0.3 0.3 0.3
PhD-SNP disease neutral neutral neutral disease disease
PhD-SNP score 0.64 0.33 0.37 0.45 0.52 0.52
SNAP neutral neutral neutral neutral neutral neutral
SNAP score 0.43 0.25 0.38 0.28 0.28 0.28
Meta-SNP disease neutral neutral neutral disease disease
Meta-SNP score 0.5 0.44 0.43 0.49 0.5 0.5
Meta-SNP RI 0 1 1 0 0 0
CAROL neutral neutral neutral neutral neutral neutral
CAROL score 0.18 0.38 0.37 0.88 0.39 0.39
Condel deleterious deleterious deleterious neutral deleterious deleterious
Condel score 0.91 0.79 0.59 0.27 0.63 0.63
COVEC WMV neutral neutral neutral neutral neutral neutral
COVEC WMV score -3 -6 -6 -3 -6 -6
MtoolBox neutral neutral neutral deleterious neutral neutral
MtoolBox DS 0.27 0.16 0.37 0.5 0.38 0.38
PolyPhen2 transf medium impact medium impact medium impact medium impact medium impact medium impact
PolyPhen2 transf score -0.13 0.84 -0.6 -0.88 -0.32 -0.32
SIFT_transf high impact medium impact medium impact medium impact medium impact medium impact
SIFT transf score 1.96 0.36 0.36 -0.21 0.29 0.29
MutationAssessor transf medium impact medium impact medium impact medium impact medium impact medium impact
MutationAssessor transf score 0.52 -0.04 -0.71 -0.27 -0.06 -0.06
CHASM pvalue 0.42 0.36 0.2 0.19 0.34 0.34
CHASM FDR 0.8 0.8 0.8 0.8 0.8 0.8
APOGEE bootstrap consensus N N N N N N
APOGEE bootstrap mean probability (mp) 0.25 0.36 0.3 0.41 0.38 0.38
SNPDryad score 0.74 0.59 0.75 0.78 0.59 0.59
MutationTaster polymorphism polymorphism polymorphism polymorphism polymorphism polymorphism
MutationTaster score 1 1 1 1 1 1
DEOGEN score 0.02 0.01 0.07 0.07 0.02 0.02
Mitoclass.1 neutral neutral neutral neutral neutral neutral
dbSNP 151 id . . . . . rs878950749
ClinVar June2018 ClinSig . . . . . .
ClinVar June2018 ClnDBN . . . . . .
ClinVar June2018 ClnAllele id . . . . . .
ClinVar June2018 ClnDSDB . . . . . .
COSMIC 87 . . . . . .
CPD candidate . . . . . .
CPD frequency . . . . . .
Mitomap Allele . . . . . .
Mitomap Phenotype . . . . . .
Mitomap Homoplasmy . . . . . .
Mitomap Heteroplasmy . . . . . .
Mitomap Status . . . . . .
Mitomap NRef . . . . . .
Classification Clinvar . . . . . N
Classification Mitomap . . . . . .
Classification Global . . . . . N
Classification Global . . . . . N
EV Mutation MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669
Site A InterP ND1_62 ND1_62 ND1_62 ND1_62 ND1_62 ND1_62
Site B InterP ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7
Covariation Score InterP mfDCA:26.6542;mfDCA:32.4636;mfDCA:33.2815;cMI:49.818882;cMI:36.386547;cMI:34.763653;cMI:34.450066;cMI:33.975521;cMI:33.017914;cMI:32.129005;cMI:31.909626;cMI:24.879795;cMI:54.948978;cMI:49.440613;cMI:49.301678;cMI:31.775438;cMI:30.591269;cMI:29.552435;cMI:29.137415;cMI:49.494175;cMI:47.679272;cMI:47.143593 mfDCA:26.6542;mfDCA:32.4636;mfDCA:33.2815;cMI:49.818882;cMI:36.386547;cMI:34.763653;cMI:34.450066;cMI:33.975521;cMI:33.017914;cMI:32.129005;cMI:31.909626;cMI:24.879795;cMI:54.948978;cMI:49.440613;cMI:49.301678;cMI:31.775438;cMI:30.591269;cMI:29.552435;cMI:29.137415;cMI:49.494175;cMI:47.679272;cMI:47.143593 mfDCA:26.6542;mfDCA:32.4636;mfDCA:33.2815;cMI:49.818882;cMI:36.386547;cMI:34.763653;cMI:34.450066;cMI:33.975521;cMI:33.017914;cMI:32.129005;cMI:31.909626;cMI:24.879795;cMI:54.948978;cMI:49.440613;cMI:49.301678;cMI:31.775438;cMI:30.591269;cMI:29.552435;cMI:29.137415;cMI:49.494175;cMI:47.679272;cMI:47.143593 mfDCA:26.6542;mfDCA:32.4636;mfDCA:33.2815;cMI:49.818882;cMI:36.386547;cMI:34.763653;cMI:34.450066;cMI:33.975521;cMI:33.017914;cMI:32.129005;cMI:31.909626;cMI:24.879795;cMI:54.948978;cMI:49.440613;cMI:49.301678;cMI:31.775438;cMI:30.591269;cMI:29.552435;cMI:29.137415;cMI:49.494175;cMI:47.679272;cMI:47.143593 mfDCA:26.6542;mfDCA:32.4636;mfDCA:33.2815;cMI:49.818882;cMI:36.386547;cMI:34.763653;cMI:34.450066;cMI:33.975521;cMI:33.017914;cMI:32.129005;cMI:31.909626;cMI:24.879795;cMI:54.948978;cMI:49.440613;cMI:49.301678;cMI:31.775438;cMI:30.591269;cMI:29.552435;cMI:29.137415;cMI:49.494175;cMI:47.679272;cMI:47.143593 mfDCA:26.6542;mfDCA:32.4636;mfDCA:33.2815;cMI:49.818882;cMI:36.386547;cMI:34.763653;cMI:34.450066;cMI:33.975521;cMI:33.017914;cMI:32.129005;cMI:31.909626;cMI:24.879795;cMI:54.948978;cMI:49.440613;cMI:49.301678;cMI:31.775438;cMI:30.591269;cMI:29.552435;cMI:29.137415;cMI:49.494175;cMI:47.679272;cMI:47.143593
Site A IntraP ND1_62 ND1_62 ND1_62 ND1_62 ND1_62 ND1_62
Site B IntraP ND1_161;ND1_87;ND1_153;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 ND1_161;ND1_87;ND1_153;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 ND1_161;ND1_87;ND1_153;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 ND1_161;ND1_87;ND1_153;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 ND1_161;ND1_87;ND1_153;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 ND1_161;ND1_87;ND1_153;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249
Covariation Score IntraP cMI:19.377666;cMI:15.746119;cMI:15.655493;cMI:15.294185;cMI:15.04784;cMI:14.834477;cMI:14.592816;cMI:14.04824;cMI:13.877844;cMI:13.72355;cMI:13.419802;cMI:13.405388 cMI:19.377666;cMI:15.746119;cMI:15.655493;cMI:15.294185;cMI:15.04784;cMI:14.834477;cMI:14.592816;cMI:14.04824;cMI:13.877844;cMI:13.72355;cMI:13.419802;cMI:13.405388 cMI:19.377666;cMI:15.746119;cMI:15.655493;cMI:15.294185;cMI:15.04784;cMI:14.834477;cMI:14.592816;cMI:14.04824;cMI:13.877844;cMI:13.72355;cMI:13.419802;cMI:13.405388 cMI:19.377666;cMI:15.746119;cMI:15.655493;cMI:15.294185;cMI:15.04784;cMI:14.834477;cMI:14.592816;cMI:14.04824;cMI:13.877844;cMI:13.72355;cMI:13.419802;cMI:13.405388 cMI:19.377666;cMI:15.746119;cMI:15.655493;cMI:15.294185;cMI:15.04784;cMI:14.834477;cMI:14.592816;cMI:14.04824;cMI:13.877844;cMI:13.72355;cMI:13.419802;cMI:13.405388 cMI:19.377666;cMI:15.746119;cMI:15.655493;cMI:15.294185;cMI:15.04784;cMI:14.834477;cMI:14.592816;cMI:14.04824;cMI:13.877844;cMI:13.72355;cMI:13.419802;cMI:13.405388
CPD AA ref . . . . . .
CPD AA alt . . . . . .
CPD aln pos . . . . . .
CPD Species name . . . . . .
CPD RefSeq Protein ID . . . . . .
CPD Ncbi Taxon ID . . . . . .
DDG intra MT-ND1:K62E:A249S:1.04071:0.581859:0.416877;MT-ND1:K62E:A249P:-0.397685:0.581859:-0.969457;MT-ND1:K62E:A249V:0.99437:0.581859:0.387706;MT-ND1:K62E:A249G:0.847108:0.581859:0.24999;MT-ND1:K62E:A249E:0.585371:0.581859:-0.081467;MT-ND1:K62E:A249T:1.1826:0.581859:0.585672;MT-ND1:K62E:N93T:0.732472:0.581859:0.161189;MT-ND1:K62E:N93H:0.18544:0.581859:-0.430894;MT-ND1:K62E:N93K:-0.0759206:0.581859:-0.753586;MT-ND1:K62E:N93I:0.103405:0.581859:-0.528503;MT-ND1:K62E:N93Y:-0.445122:0.581859:-1.03778;MT-ND1:K62E:N93S:0.668844:0.581859:0.0416942;MT-ND1:K62E:N93D:0.824512:0.581859:0.206064;MT-ND1:K62E:P2R:1.25558:0.581859:0.63914;MT-ND1:K62E:P2T:0.79863:0.581859:0.178692;MT-ND1:K62E:P2H:1.50412:0.581859:0.926272;MT-ND1:K62E:P2L:0.757612:0.581859:0.109703;MT-ND1:K62E:P2A:1.06867:0.581859:0.449523;MT-ND1:K62E:P2S:0.676861:0.581859:0.119094 MT-ND1:K62Q:A249G:0.776656:0.490174:0.24999;MT-ND1:K62Q:A249E:0.44095:0.490174:-0.081467;MT-ND1:K62Q:A249P:-0.510834:0.490174:-0.969457;MT-ND1:K62Q:A249V:0.839957:0.490174:0.387706;MT-ND1:K62Q:A249T:1.09273:0.490174:0.585672;MT-ND1:K62Q:N93D:0.669307:0.490174:0.206064;MT-ND1:K62Q:N93Y:-0.546119:0.490174:-1.03778;MT-ND1:K62Q:N93S:0.561219:0.490174:0.0416942;MT-ND1:K62Q:N93H:0.0321485:0.490174:-0.430894;MT-ND1:K62Q:N93T:0.648411:0.490174:0.161189;MT-ND1:K62Q:N93I:-0.0709373:0.490174:-0.528503;MT-ND1:K62Q:A249S:0.907528:0.490174:0.416877;MT-ND1:K62Q:N93K:-0.238147:0.490174:-0.753586;MT-ND1:K62Q:P2L:0.550066:0.490174:0.109703;MT-ND1:K62Q:P2T:0.666497:0.490174:0.178692;MT-ND1:K62Q:P2A:0.932338:0.490174:0.449523;MT-ND1:K62Q:P2S:0.605205:0.490174:0.119094;MT-ND1:K62Q:P2H:1.37583:0.490174:0.926272;MT-ND1:K62Q:P2R:1.19271:0.490174:0.63914 MT-ND1:K62T:A249S:1.17339:0.677214:0.416877;MT-ND1:K62T:A249T:1.35942:0.677214:0.585672;MT-ND1:K62T:A249V:1.17436:0.677214:0.387706;MT-ND1:K62T:A249P:-0.19227:0.677214:-0.969457;MT-ND1:K62T:A249E:0.779932:0.677214:-0.081467;MT-ND1:K62T:A249G:0.961282:0.677214:0.24999;MT-ND1:K62T:N93I:0.26794:0.677214:-0.528503;MT-ND1:K62T:N93T:0.832255:0.677214:0.161189;MT-ND1:K62T:N93S:0.765149:0.677214:0.0416942;MT-ND1:K62T:N93K:0.0471628:0.677214:-0.753586;MT-ND1:K62T:N93D:0.960075:0.677214:0.206064;MT-ND1:K62T:N93H:0.453655:0.677214:-0.430894;MT-ND1:K62T:N93Y:-0.237635:0.677214:-1.03778;MT-ND1:K62T:P2H:1.65574:0.677214:0.926272;MT-ND1:K62T:P2A:1.19454:0.677214:0.449523;MT-ND1:K62T:P2T:0.992374:0.677214:0.178692;MT-ND1:K62T:P2R:1.47925:0.677214:0.63914;MT-ND1:K62T:P2S:0.803022:0.677214:0.119094;MT-ND1:K62T:P2L:0.628657:0.677214:0.109703 MT-ND1:K62M:A249G:-0.871784:-1.08529:0.24999;MT-ND1:K62M:A249E:-1.00519:-1.08529:-0.081467;MT-ND1:K62M:A249S:-0.659035:-1.08529:0.416877;MT-ND1:K62M:A249P:-2.05651:-1.08529:-0.969457;MT-ND1:K62M:A249V:-0.682354:-1.08529:0.387706;MT-ND1:K62M:A249T:-0.493693:-1.08529:0.585672;MT-ND1:K62M:N93S:-1.05384:-1.08529:0.0416942;MT-ND1:K62M:N93D:-0.901726:-1.08529:0.206064;MT-ND1:K62M:N93Y:-2.12038:-1.08529:-1.03778;MT-ND1:K62M:N93H:-1.48116:-1.08529:-0.430894;MT-ND1:K62M:N93K:-1.80338:-1.08529:-0.753586;MT-ND1:K62M:N93I:-1.62462:-1.08529:-0.528503;MT-ND1:K62M:N93T:-0.884002:-1.08529:0.161189;MT-ND1:K62M:P2S:-0.930917:-1.08529:0.119094;MT-ND1:K62M:P2A:-0.641795:-1.08529:0.449523;MT-ND1:K62M:P2L:-1.02882:-1.08529:0.109703;MT-ND1:K62M:P2H:-0.203589:-1.08529:0.926272;MT-ND1:K62M:P2T:-0.806913:-1.08529:0.178692;MT-ND1:K62M:P2R:-0.413394:-1.08529:0.63914 MT-ND1:K62N:A249S:1.13755:0.851927:0.416877;MT-ND1:K62N:A249E:0.842145:0.851927:-0.081467;MT-ND1:K62N:A249V:1.18013:0.851927:0.387706;MT-ND1:K62N:A249G:0.800294:0.851927:0.24999;MT-ND1:K62N:A249T:1.40202:0.851927:0.585672;MT-ND1:K62N:A249P:-0.0113826:0.851927:-0.969457;MT-ND1:K62N:N93Y:-0.243065:0.851927:-1.03778;MT-ND1:K62N:N93D:1.1439:0.851927:0.206064;MT-ND1:K62N:N93H:0.251854:0.851927:-0.430894;MT-ND1:K62N:N93K:0.122694:0.851927:-0.753586;MT-ND1:K62N:N93S:0.928952:0.851927:0.0416942;MT-ND1:K62N:N93I:0.0884897:0.851927:-0.528503;MT-ND1:K62N:N93T:1.01233:0.851927:0.161189;MT-ND1:K62N:P2A:1.27791:0.851927:0.449523;MT-ND1:K62N:P2S:0.939521:0.851927:0.119094;MT-ND1:K62N:P2L:0.733007:0.851927:0.109703;MT-ND1:K62N:P2T:1.11195:0.851927:0.178692;MT-ND1:K62N:P2R:1.50251:0.851927:0.63914;MT-ND1:K62N:P2H:1.68274:0.851927:0.926272 MT-ND1:K62N:A249S:1.13755:0.851927:0.416877;MT-ND1:K62N:A249E:0.842145:0.851927:-0.081467;MT-ND1:K62N:A249V:1.18013:0.851927:0.387706;MT-ND1:K62N:A249G:0.800294:0.851927:0.24999;MT-ND1:K62N:A249T:1.40202:0.851927:0.585672;MT-ND1:K62N:A249P:-0.0113826:0.851927:-0.969457;MT-ND1:K62N:N93Y:-0.243065:0.851927:-1.03778;MT-ND1:K62N:N93D:1.1439:0.851927:0.206064;MT-ND1:K62N:N93H:0.251854:0.851927:-0.430894;MT-ND1:K62N:N93K:0.122694:0.851927:-0.753586;MT-ND1:K62N:N93S:0.928952:0.851927:0.0416942;MT-ND1:K62N:N93I:0.0884897:0.851927:-0.528503;MT-ND1:K62N:N93T:1.01233:0.851927:0.161189;MT-ND1:K62N:P2A:1.27791:0.851927:0.449523;MT-ND1:K62N:P2S:0.939521:0.851927:0.119094;MT-ND1:K62N:P2L:0.733007:0.851927:0.109703;MT-ND1:K62N:P2T:1.11195:0.851927:0.178692;MT-ND1:K62N:P2R:1.50251:0.851927:0.63914;MT-ND1:K62N:P2H:1.68274:0.851927:0.926272
DDG intra interface . . . . . .
DDG inter MT-ND1:MT-ND3:5lc5:H:A:K62E:L79P:3.60749:0.412649542:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79Q:2.87511:0.412649542:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79R:4.30188:0.412649542:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79V:2.28026:0.412649542:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79M:0.09989:0.412649542:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45F:0.35208:0.412649542:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45A:0.6052:0.412649542:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45C:0.17853:0.412649542:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45P:-0.63057:0.412649542:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45T:0.10504:0.412649542:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45Y:0.51928:0.412649542:-0.209069446;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79P:4.50268:0.301341236:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79Q:2.36948:0.301341236:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79R:5.50838:0.301341236:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79V:1.39489:0.301341236:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79M:-0.37051:0.301341236:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45F:0.36466:0.301341236:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45A:0.47682:0.301341236:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45C:0.01122:0.301341236:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45P:0.03594:0.301341236:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45T:0.55431:0.301341236:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45Y:0.95424:0.301341236:0.377010345;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79P:4.743:0.575948715:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79Q:2.45156:0.575948715:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79R:5.67142:0.575948715:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79V:1.63669:0.575948715:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79M:-0.06359:0.575948715:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45F:1.10355:0.575948715:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45A:1.20875:0.575948715:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45C:1.04964:0.575948715:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45P:1.13652:0.575948715:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45T:0.90794:0.575948715:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45Y:1.06902:0.575948715:0.507420719 MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79V:1.62769:-0.241339117:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79M:-0.76247:-0.241339117:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79Q:2.23228:-0.241339117:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79R:4.12982:-0.241339117:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79P:3.41535:-0.241339117:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45P:-1.35861:-0.241339117:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45A:-0.4992:-0.241339117:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45Y:-0.52016:-0.241339117:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45C:-0.63482:-0.241339117:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45T:-0.06226:-0.241339117:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45F:-0.52595:-0.241339117:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79V:1.27141:-0.0290084835:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79M:-0.78372:-0.0290084835:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79Q:2.05022:-0.0290084835:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79R:5.26848:-0.0290084835:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79P:3.94707:-0.0290084835:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45P:-0.30247:-0.0290084835:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45A:-0.03384:-0.0290084835:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45Y:0.34942:-0.0290084835:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45C:-0.31279:-0.0290084835:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45T:0.1782:-0.0290084835:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45F:-0.08954:-0.0290084835:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79V:1.22648:0.0151092531:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79M:-0.52285:0.0151092531:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79Q:1.86838:0.0151092531:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79R:4.79778:0.0151092531:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79P:4.04125:0.0151092531:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45P:0.70032:0.0151092531:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45A:0.53665:0.0151092531:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45Y:0.52526:0.0151092531:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45C:0.51468:0.0151092531:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45T:0.27175:0.0151092531:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45F:0.54544:0.0151092531:0.507999063 MT-ND1:MT-ND3:5lc5:H:A:K62T:L79V:2.6662:0.832580209:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79R:4.85777:0.832580209:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79M:0.3109:0.832580209:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79P:4.3808:0.832580209:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79Q:3.27382:0.832580209:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45P:-0.34137:0.832580209:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45Y:0.54121:0.832580209:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45C:0.2024:0.832580209:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45A:0.65075:0.832580209:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45T:0.92303:0.832580209:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45F:0.4885:0.832580209:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79V:1.36653:0.183251187:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79R:5.42788:0.183251187:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79M:-0.51625:0.183251187:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79P:4.04873:0.183251187:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79Q:2.32473:0.183251187:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45P:-0.15744:0.183251187:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45Y:0.36945:0.183251187:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45C:-0.11214:0.183251187:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45A:0.0492:0.183251187:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45T:0.1089:0.183251187:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45F:0.56165:0.183251187:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79V:1.33255:0.109650038:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79R:4.66289:0.109650038:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79M:-0.50269:0.109650038:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79P:4.13879:0.109650038:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79Q:1.99682:0.109650038:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45P:0.63491:0.109650038:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45Y:0.59073:0.109650038:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45C:0.53656:0.109650038:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45A:0.59559:0.109650038:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45T:0.66071:0.109650038:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45F:0.42017:0.109650038:0.507999063 MT-ND1:MT-ND3:5lc5:H:A:K62M:L79Q:2.44352:-0.217529684:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62M:L79M:-0.57962:-0.217529684:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62M:L79R:4.29266:-0.217529684:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62M:L79V:1.70915:-0.217529684:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62M:L79P:3.36341:-0.217529684:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62M:S45Y:-0.42594:-0.217529684:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62M:S45A:-0.43482:-0.217529684:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62M:S45P:-1.30943:-0.217529684:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62M:S45C:-0.69975:-0.217529684:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62M:S45T:0.16331:-0.217529684:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62M:S45F:-0.40484:-0.217529684:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62M:L79Q:2.07633:-0.012728882:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62M:L79M:-0.65982:-0.012728882:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62M:L79R:5.38456:-0.012728882:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62M:L79V:1.42365:-0.012728882:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62M:L79P:4.01617:-0.012728882:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62M:S45Y:0.42674:-0.012728882:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62M:S45A:-0.02866:-0.012728882:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62M:S45P:-0.29642:-0.012728882:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62M:S45C:-0.04728:-0.012728882:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62M:S45T:0.2066:-0.012728882:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62M:S45F:0.10054:-0.012728882:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62M:L79Q:1.98528:0.0504192337:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62M:L79M:-0.42606:0.0504192337:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62M:L79R:4.90435:0.0504192337:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62M:L79V:1.29942:0.0504192337:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62M:L79P:4.14535:0.0504192337:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62M:S45Y:0.57198:0.0504192337:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62M:S45A:0.60852:0.0504192337:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62M:S45P:0.68073:0.0504192337:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62M:S45C:0.45475:0.0504192337:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62M:S45T:0.57074:0.0504192337:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62M:S45F:0.58069:0.0504192337:0.507999063 MT-ND1:MT-ND3:5lc5:H:A:K62N:L79M:0.36209:0.846379876:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79R:4.67497:0.846379876:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79Q:3.40628:0.846379876:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79P:4.49723:0.846379876:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79V:2.52098:0.846379876:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45Y:0.51875:0.846379876:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45A:0.80299:0.846379876:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45C:0.47653:0.846379876:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45F:0.5255:0.846379876:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45T:0.92636:0.846379876:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45P:-0.31288:0.846379876:-1.09178007;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79M:-0.21654:0.465351105:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79R:5.44033:0.465351105:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79Q:2.60588:0.465351105:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79P:4.43886:0.465351105:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79V:1.83971:0.465351105:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45Y:0.65123:0.465351105:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45A:0.44287:0.465351105:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45C:0.41846:0.465351105:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45F:0.64931:0.465351105:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45T:0.60346:0.465351105:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45P:0.17598:0.465351105:-0.288380057;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79M:-0.05793:0.452788532:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79R:4.4806:0.452788532:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79Q:2.31552:0.452788532:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79P:4.57315:0.452788532:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79V:1.70418:0.452788532:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45Y:0.96298:0.452788532:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45A:1.01432:0.452788532:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45C:0.92703:0.452788532:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45F:0.97663:0.452788532:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45T:1.04835:0.452788532:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45P:1.25505:0.452788532:0.854759216 MT-ND1:MT-ND3:5lc5:H:A:K62N:L79M:0.36209:0.846379876:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79R:4.67497:0.846379876:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79Q:3.40628:0.846379876:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79P:4.49723:0.846379876:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62N:L79V:2.52098:0.846379876:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45Y:0.51875:0.846379876:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45A:0.80299:0.846379876:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45C:0.47653:0.846379876:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45F:0.5255:0.846379876:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45T:0.92636:0.846379876:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62N:S45P:-0.31288:0.846379876:-1.09178007;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79M:-0.21654:0.465351105:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79R:5.44033:0.465351105:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79Q:2.60588:0.465351105:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79P:4.43886:0.465351105:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62N:L79V:1.83971:0.465351105:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45Y:0.65123:0.465351105:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45A:0.44287:0.465351105:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45C:0.41846:0.465351105:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45F:0.64931:0.465351105:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45T:0.60346:0.465351105:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62N:S45P:0.17598:0.465351105:-0.288380057;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79M:-0.05793:0.452788532:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79R:4.4806:0.452788532:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79Q:2.31552:0.452788532:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79P:4.57315:0.452788532:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62N:L79V:1.70418:0.452788532:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45Y:0.96298:0.452788532:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45A:1.01432:0.452788532:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45C:0.92703:0.452788532:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45F:0.97663:0.452788532:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45T:1.04835:0.452788532:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62N:S45P:1.25505:0.452788532:0.854759216
For more info, please check the output legend.
For more info, please check the output legend.
For more info, please check the output legend.
For more info, please check the output legend.
For more info, please check the output legend.