news model
license
| ~ | 3490 (A/G) | 3490 (A/C) | 3491 (A/C) | 3491 (A/T) | 3492 (A/T) | 3492 (A/C) |
|---|---|---|---|---|---|---|
| ~ | 3490 (Aaa/Gaa) | 3490 (Aaa/Caa) | 3491 (aAa/aCa) | 3491 (aAa/aTa) | 3492 (aaA/aaT) | 3492 (aaA/aaC) |
| Chr | chrM | chrM | chrM | chrM | chrM | chrM |
| Start | 3490 | 3490 | 3491 | 3491 | 3492 | 3492 |
| End | 3490 | 3490 | 3491 | 3491 | 3492 | 3492 |
| Ref | A | A | A | A | A | A |
| Alt | G | C | C | T | T | C |
| MitImpact id | MI.11141 | MI.11142 | MI.11143 | MI.11144 | MI.11145 | MI.11146 |
| Gene symbol | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 |
| Respiratory Chain complex | I | I | I | I | I | I |
| Ensembl gene id | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 |
| Ensembl protein id | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 |
| Ensembl transcript id | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 |
| Uniprot name | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN |
| Uniprot id | P03886 | P03886 | P03886 | P03886 | P03886 | P03886 |
| Ncbi gene id | 4535 | 4535 | 4535 | 4535 | 4535 | 4535 |
| Ncbi protein id | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 |
| Gene position | 184 | 184 | 185 | 185 | 186 | 186 |
| AA position | 62 | 62 | 62 | 62 | 62 | 62 |
| AA ref | K | K | K | K | K | K |
| AA alt | E | Q | T | M | N | N |
| Codon substitution | Aaa/Gaa | Aaa/Caa | aAa/aCa | aAa/aTa | aaA/aaT | aaA/aaC |
| PhyloP 100V | -3 | -3 | 0.22 | 0.22 | 0.45 | 0.45 |
| PhastCons 100V | 0 | 0 | 0 | 0 | 0 | 0 |
| PolyPhen2 | benign | benign | benign | possibly_damaging | benign | benign |
| PolyPhen2 score | 0.18 | 0.02 | 0.41 | 0.58 | 0.26 | 0.26 |
| SIFT | neutral | neutral | neutral | neutral | neutral | neutral |
| SIFT score | 1 | 0.59 | 0.59 | 0.12 | 0.51 | 0.51 |
| FatHmm | neutral | neutral | neutral | neutral | neutral | neutral |
| FatHmm score | -0.79 | -0.67 | 1.17 | -0.08 | -1.09 | -1.09 |
| FatHmmW | neutral | neutral | neutral | neutral | neutral | neutral |
| FatHmmW score | 2.77 | 2.76 | 2.81 | 2.74 | 2.75 | 2.75 |
| PROVEAN | neutral | neutral | deleterious | neutral | neutral | neutral |
| PROVEAN score | -1.36 | -0.29 | -2.5 | -2.33 | -1.59 | -1.59 |
| MutationAssessor | medium impact | low impact | neutral impact | low impact | low impact | low impact |
| MutationAssessor score | 1.95 | 1.32 | 0.55 | 1.05 | 1.29 | 1.29 |
| EFIN SP | neutral | neutral | neutral | neutral | neutral | neutral |
| EFIN SP score | 0.84 | 0.82 | 0.69 | 0.71 | 0.68 | 0.68 |
| EFIN HD | neutral | neutral | neutral | neutral | neutral | neutral |
| EFIN HD score | 0.7 | 0.97 | 0.66 | 0.61 | 0.67 | 0.67 |
| CADD | deleterious | deleterious | deleterious | deleterious | deleterious | deleterious |
| CADD score | 3.92 | 2.2 | 3.51 | 3.74 | 3.82 | 3.75 |
| CADD phred | 23.5 | 17.49 | 23.1 | 23.3 | 23.4 | 23.3 |
| VEST pvalue | 0.26 | 0.39 | 0.14 | 0.12 | 0.5 | 0.5 |
| VEST FDR | 0.45 | 0.5 | 0.4 | 0.4 | 0.6 | 0.6 |
| PANTHER | neutral | neutral | neutral | neutral | neutral | neutral |
| PANTHER score | 0.24 | 0.27 | 0.16 | 0.3 | 0.3 | 0.3 |
| PhD-SNP | disease | neutral | neutral | neutral | disease | disease |
| PhD-SNP score | 0.64 | 0.33 | 0.37 | 0.45 | 0.52 | 0.52 |
| SNAP | neutral | neutral | neutral | neutral | neutral | neutral |
| SNAP score | 0.43 | 0.25 | 0.38 | 0.28 | 0.28 | 0.28 |
| Meta-SNP | disease | neutral | neutral | neutral | disease | disease |
| Meta-SNP score | 0.5 | 0.44 | 0.43 | 0.49 | 0.5 | 0.5 |
| Meta-SNP RI | 0 | 1 | 1 | 0 | 0 | 0 |
| CAROL | neutral | neutral | neutral | neutral | neutral | neutral |
| CAROL score | 0.18 | 0.38 | 0.37 | 0.88 | 0.39 | 0.39 |
| Condel | deleterious | deleterious | deleterious | neutral | deleterious | deleterious |
| Condel score | 0.91 | 0.79 | 0.59 | 0.27 | 0.63 | 0.63 |
| COVEC WMV | neutral | neutral | neutral | neutral | neutral | neutral |
| COVEC WMV score | -3 | -6 | -6 | -3 | -6 | -6 |
| MtoolBox | neutral | neutral | neutral | deleterious | neutral | neutral |
| MtoolBox DS | 0.27 | 0.16 | 0.37 | 0.5 | 0.38 | 0.38 |
| PolyPhen2 transf | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| PolyPhen2 transf score | -0.13 | 0.84 | -0.6 | -0.88 | -0.32 | -0.32 |
| SIFT_transf | high impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| SIFT transf score | 1.96 | 0.36 | 0.36 | -0.21 | 0.29 | 0.29 |
| MutationAssessor transf | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| MutationAssessor transf score | 0.52 | -0.04 | -0.71 | -0.27 | -0.06 | -0.06 |
| CHASM pvalue | 0.42 | 0.36 | 0.2 | 0.19 | 0.34 | 0.34 |
| CHASM FDR | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 |
| APOGEE | Likely-benign | Likely-benign | Likely-benign | VUS | Likely-benign | Likely-benign |
| APOGEE score | 0.1200800382858785 | 0.1538174251501678 | 0.2506835078457387 | 0.2843369800006492 | 0.185893546384039 | 0.185893546384039 |
| SNPDryad score | 0.74 | 0.59 | 0.75 | 0.78 | 0.59 | 0.59 |
| MutationTaster | polymorphism | polymorphism | polymorphism | polymorphism | polymorphism | polymorphism |
| MutationTaster score | 1 | 1 | 1 | 1 | 1 | 1 |
| DEOGEN2 score | 0.02 | 0.01 | 0.07 | 0.07 | 0.02 | 0.02 |
| Mitoclass.1 | neutral | neutral | neutral | neutral | neutral | neutral |
| dbSNP 155 id | . | . | . | . | . | rs878950749 |
| ClinVar October2021 Variation id | . | . | . | . | . | . |
| ClinVar October2021 CLNSIG | . | . | . | . | . | . |
| ClinVar October2021 CLNDN | . | . | . | . | . | . |
| ClinVar October2021 CLNDISDB | . | . | . | . | . | . |
| COSMIC 90 | . | . | . | . | . | . |
| MITOMAP Allele | . | . | . | . | . | . |
| MITOMAP Disease Het/Hom | . | . | . | . | . | . |
| MITOMAP Disease Clinical info | . | . | . | . | . | . |
| MITOMAP Disease Status | . | . | . | . | . | . |
| MITOMAP Disease GenBank Freq | . | . | . | . | . | . |
| MITOMAP Disease GenBank Seqs | . | . | . | . | . | . |
| MITOMAP Disease GenBank Curated refs | . | . | . | . | . | . |
| MITOMAP General GenBank Freq | . | . | . | . | . | 0.002% |
| MITOMAP General GenBank Seqs | . | . | . | . | . | 1 |
| MITOMAP General Curated refs | . | . | . | . | . | 1 |
| gnomAD 3.1 filter | . | . | . | . | . | npg |
| gnomAD 3.1 AC Homo | . | . | . | . | . | 0 |
| gnomAD 3.1 AC Het | . | . | . | . | . | 0 |
| gnomAD 3.1 AF Hom | . | . | . | . | . | 0 |
| gnomAD 3.1 AF Het | . | . | . | . | . | 0 |
| gnomAD 3.1 AN | . | . | . | . | . | 56222 |
| HelixMTdb AC Hom | . | . | . | . | . | . |
| HelixMTdb AF Hom | . | . | . | . | . | . |
| HelixMTdb AC Het | . | . | . | . | . | . |
| HelixMTdb AF Het | . | . | . | . | . | . |
| HelixMTdb mean ARF | . | . | . | . | . | . | HelixMTdb max ARF | . | . | . | . | . | . |
| EVmutation | MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 | MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 | MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 | MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 | MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 | MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
| Site A InterP | ND1_62 | ND1_62 | ND1_62 | ND1_62 | ND1_62 | ND1_62 |
| Site B InterP | ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 | ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 | ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 | ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 | ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 | ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
| Covariation Score InterP | mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 | mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 | mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 | mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 | mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 | mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
| Site A IntraP | ND1_62 | ND1_62 | ND1_62 | ND1_62 | ND1_62 | ND1_62 |
| Site B IntraP | ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 | ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 | ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 | ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 | ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 | ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
| Covariation Score IntraP | cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 | cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 | cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 | cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 | cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 | cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
| CPD AA ref | . | . | . | . | . | . |
| CPD AA alt | . | . | . | . | . | . |
| CPD Aln pos | . | . | . | . | . | . |
| CPD Frequency | . | . | . | . | . | . |
| CPD Species name | . | . | . | . | . | . |
| CPD RefSeq Protein ID | . | . | . | . | . | . |
| CPD Ncbi Taxon id | . | . | . | . | . | . |
| DDG intra | MT-ND1:K62E:A249S:1.04071:0.581859:0.416877;MT-ND1:K62E:A249P:-0.397685:0.581859:-0.969457;MT-ND1:K62E:A249V:0.99437:0.581859:0.387706;MT-ND1:K62E:A249G:0.847108:0.581859:0.24999;MT-ND1:K62E:A249E:0.585371:0.581859:-0.081467;MT-ND1:K62E:A249T:1.1826:0.581859:0.585672;MT-ND1:K62E:N93T:0.732472:0.581859:0.161189;MT-ND1:K62E:N93H:0.18544:0.581859:-0.430894;MT-ND1:K62E:N93K:-0.0759206:0.581859:-0.753586;MT-ND1:K62E:N93I:0.103405:0.581859:-0.528503;MT-ND1:K62E:N93Y:-0.445122:0.581859:-1.03778;MT-ND1:K62E:N93S:0.668844:0.581859:0.0416942;MT-ND1:K62E:N93D:0.824512:0.581859:0.206064;MT-ND1:K62E:P2R:1.25558:0.581859:0.63914;MT-ND1:K62E:P2T:0.79863:0.581859:0.178692;MT-ND1:K62E:P2H:1.50412:0.581859:0.926272;MT-ND1:K62E:P2L:0.757612:0.581859:0.109703;MT-ND1:K62E:P2A:1.06867:0.581859:0.449523;MT-ND1:K62E:P2S:0.676861:0.581859:0.119094 | MT-ND1:K62Q:A249G:0.776656:0.490174:0.24999;MT-ND1:K62Q:A249E:0.44095:0.490174:-0.081467;MT-ND1:K62Q:A249P:-0.510834:0.490174:-0.969457;MT-ND1:K62Q:A249V:0.839957:0.490174:0.387706;MT-ND1:K62Q:A249T:1.09273:0.490174:0.585672;MT-ND1:K62Q:N93D:0.669307:0.490174:0.206064;MT-ND1:K62Q:N93Y:-0.546119:0.490174:-1.03778;MT-ND1:K62Q:N93S:0.561219:0.490174:0.0416942;MT-ND1:K62Q:N93H:0.0321485:0.490174:-0.430894;MT-ND1:K62Q:N93T:0.648411:0.490174:0.161189;MT-ND1:K62Q:N93I:-0.0709373:0.490174:-0.528503;MT-ND1:K62Q:A249S:0.907528:0.490174:0.416877;MT-ND1:K62Q:N93K:-0.238147:0.490174:-0.753586;MT-ND1:K62Q:P2L:0.550066:0.490174:0.109703;MT-ND1:K62Q:P2T:0.666497:0.490174:0.178692;MT-ND1:K62Q:P2A:0.932338:0.490174:0.449523;MT-ND1:K62Q:P2S:0.605205:0.490174:0.119094;MT-ND1:K62Q:P2H:1.37583:0.490174:0.926272;MT-ND1:K62Q:P2R:1.19271:0.490174:0.63914 | MT-ND1:K62T:A249S:1.17339:0.677214:0.416877;MT-ND1:K62T:A249T:1.35942:0.677214:0.585672;MT-ND1:K62T:A249V:1.17436:0.677214:0.387706;MT-ND1:K62T:A249P:-0.19227:0.677214:-0.969457;MT-ND1:K62T:A249E:0.779932:0.677214:-0.081467;MT-ND1:K62T:A249G:0.961282:0.677214:0.24999;MT-ND1:K62T:N93I:0.26794:0.677214:-0.528503;MT-ND1:K62T:N93T:0.832255:0.677214:0.161189;MT-ND1:K62T:N93S:0.765149:0.677214:0.0416942;MT-ND1:K62T:N93K:0.0471628:0.677214:-0.753586;MT-ND1:K62T:N93D:0.960075:0.677214:0.206064;MT-ND1:K62T:N93H:0.453655:0.677214:-0.430894;MT-ND1:K62T:N93Y:-0.237635:0.677214:-1.03778;MT-ND1:K62T:P2H:1.65574:0.677214:0.926272;MT-ND1:K62T:P2A:1.19454:0.677214:0.449523;MT-ND1:K62T:P2T:0.992374:0.677214:0.178692;MT-ND1:K62T:P2R:1.47925:0.677214:0.63914;MT-ND1:K62T:P2S:0.803022:0.677214:0.119094;MT-ND1:K62T:P2L:0.628657:0.677214:0.109703 | MT-ND1:K62M:A249G:-0.871784:-1.08529:0.24999;MT-ND1:K62M:A249E:-1.00519:-1.08529:-0.081467;MT-ND1:K62M:A249S:-0.659035:-1.08529:0.416877;MT-ND1:K62M:A249P:-2.05651:-1.08529:-0.969457;MT-ND1:K62M:A249V:-0.682354:-1.08529:0.387706;MT-ND1:K62M:A249T:-0.493693:-1.08529:0.585672;MT-ND1:K62M:N93S:-1.05384:-1.08529:0.0416942;MT-ND1:K62M:N93D:-0.901726:-1.08529:0.206064;MT-ND1:K62M:N93Y:-2.12038:-1.08529:-1.03778;MT-ND1:K62M:N93H:-1.48116:-1.08529:-0.430894;MT-ND1:K62M:N93K:-1.80338:-1.08529:-0.753586;MT-ND1:K62M:N93I:-1.62462:-1.08529:-0.528503;MT-ND1:K62M:N93T:-0.884002:-1.08529:0.161189;MT-ND1:K62M:P2S:-0.930917:-1.08529:0.119094;MT-ND1:K62M:P2A:-0.641795:-1.08529:0.449523;MT-ND1:K62M:P2L:-1.02882:-1.08529:0.109703;MT-ND1:K62M:P2H:-0.203589:-1.08529:0.926272;MT-ND1:K62M:P2T:-0.806913:-1.08529:0.178692;MT-ND1:K62M:P2R:-0.413394:-1.08529:0.63914 | MT-ND1:K62N:A249S:1.13755:0.851927:0.416877;MT-ND1:K62N:A249E:0.842145:0.851927:-0.081467;MT-ND1:K62N:A249V:1.18013:0.851927:0.387706;MT-ND1:K62N:A249G:0.800294:0.851927:0.24999;MT-ND1:K62N:A249T:1.40202:0.851927:0.585672;MT-ND1:K62N:A249P:-0.0113826:0.851927:-0.969457;MT-ND1:K62N:N93Y:-0.243065:0.851927:-1.03778;MT-ND1:K62N:N93D:1.1439:0.851927:0.206064;MT-ND1:K62N:N93H:0.251854:0.851927:-0.430894;MT-ND1:K62N:N93K:0.122694:0.851927:-0.753586;MT-ND1:K62N:N93S:0.928952:0.851927:0.0416942;MT-ND1:K62N:N93I:0.0884897:0.851927:-0.528503;MT-ND1:K62N:N93T:1.01233:0.851927:0.161189;MT-ND1:K62N:P2A:1.27791:0.851927:0.449523;MT-ND1:K62N:P2S:0.939521:0.851927:0.119094;MT-ND1:K62N:P2L:0.733007:0.851927:0.109703;MT-ND1:K62N:P2T:1.11195:0.851927:0.178692;MT-ND1:K62N:P2R:1.50251:0.851927:0.63914;MT-ND1:K62N:P2H:1.68274:0.851927:0.926272 | MT-ND1:K62N:A249S:1.13755:0.851927:0.416877;MT-ND1:K62N:A249E:0.842145:0.851927:-0.081467;MT-ND1:K62N:A249V:1.18013:0.851927:0.387706;MT-ND1:K62N:A249G:0.800294:0.851927:0.24999;MT-ND1:K62N:A249T:1.40202:0.851927:0.585672;MT-ND1:K62N:A249P:-0.0113826:0.851927:-0.969457;MT-ND1:K62N:N93Y:-0.243065:0.851927:-1.03778;MT-ND1:K62N:N93D:1.1439:0.851927:0.206064;MT-ND1:K62N:N93H:0.251854:0.851927:-0.430894;MT-ND1:K62N:N93K:0.122694:0.851927:-0.753586;MT-ND1:K62N:N93S:0.928952:0.851927:0.0416942;MT-ND1:K62N:N93I:0.0884897:0.851927:-0.528503;MT-ND1:K62N:N93T:1.01233:0.851927:0.161189;MT-ND1:K62N:P2A:1.27791:0.851927:0.449523;MT-ND1:K62N:P2S:0.939521:0.851927:0.119094;MT-ND1:K62N:P2L:0.733007:0.851927:0.109703;MT-ND1:K62N:P2T:1.11195:0.851927:0.178692;MT-ND1:K62N:P2R:1.50251:0.851927:0.63914;MT-ND1:K62N:P2H:1.68274:0.851927:0.926272 |
| DDG intra interface | . | . | . | . | . | . |
| DDG inter | MT-ND1:MT-ND3:5lc5:H:A:K62E:L79P:3.60749:0.412649542:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79Q:2.87511:0.412649542:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79R:4.30188:0.412649542:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79V:2.28026:0.412649542:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79M:0.09989:0.412649542:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45F:0.35208:0.412649542:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45A:0.6052:0.412649542:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45C:0.17853:0.412649542:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45P:-0.63057:0.412649542:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45T:0.10504:0.412649542:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45Y:0.51928:0.412649542:-0.209069446;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79P:4.50268:0.301341236:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79Q:2.36948:0.301341236:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79R:5.50838:0.301341236:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79V:1.39489:0.301341236:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79M:-0.37051:0.301341236:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45F:0.36466:0.301341236:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45A:0.47682:0.301341236:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45C:0.01122:0.301341236:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45P:0.03594:0.301341236:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45T:0.55431:0.301341236:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45Y:0.95424:0.301341236:0.377010345;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79P:4.743:0.575948715:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79Q:2.45156:0.575948715:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79R:5.67142:0.575948715:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79V:1.63669:0.575948715:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79M:-0.06359:0.575948715:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45F:1.10355:0.575948715:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45A:1.20875:0.575948715:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45C:1.04964:0.575948715:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45P:1.13652:0.575948715:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45T:0.90794:0.575948715:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45Y:1.06902:0.575948715:0.507420719 | MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79V:1.62769:-0.241339117:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79M:-0.76247:-0.241339117:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79Q:2.23228:-0.241339117:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79R:4.12982:-0.241339117:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79P:3.41535:-0.241339117:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45P:-1.35861:-0.241339117:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45A:-0.4992:-0.241339117:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45Y:-0.52016:-0.241339117:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45C:-0.63482:-0.241339117:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45T:-0.06226:-0.241339117:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45F:-0.52595:-0.241339117:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79V:1.27141:-0.0290084835:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79M:-0.78372:-0.0290084835:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79Q:2.05022:-0.0290084835:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79R:5.26848:-0.0290084835:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79P:3.94707:-0.0290084835:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45P:-0.30247:-0.0290084835:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45A:-0.03384:-0.0290084835:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45Y:0.34942:-0.0290084835:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45C:-0.31279:-0.0290084835:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45T:0.1782:-0.0290084835:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45F:-0.08954:-0.0290084835:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79V:1.22648:0.0151092531:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79M:-0.52285:0.0151092531:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79Q:1.86838:0.0151092531:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79R:4.79778:0.0151092531:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79P:4.04125:0.0151092531:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45P:0.70032:0.0151092531:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45A:0.53665:0.0151092531:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45Y:0.52526:0.0151092531:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45C:0.51468:0.0151092531:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45T:0.27175:0.0151092531:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45F:0.54544:0.0151092531:0.507999063 | MT-ND1:MT-ND3:5lc5:H:A:K62T:L79V:2.6662:0.832580209:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79R:4.85777:0.832580209:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79M:0.3109:0.832580209:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79P:4.3808:0.832580209:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79Q:3.27382:0.832580209:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45P:-0.34137:0.832580209:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45Y:0.54121:0.832580209:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45C:0.2024:0.832580209:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45A:0.65075:0.832580209:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45T:0.92303:0.832580209:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45F:0.4885:0.832580209:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79V:1.36653:0.183251187:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79R:5.42788:0.183251187:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79M:-0.51625:0.183251187:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79P:4.04873:0.183251187:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79Q:2.32473:0.183251187:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45P:-0.15744:0.183251187:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45Y:0.36945:0.183251187:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45C:-0.11214:0.183251187:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45A:0.0492:0.183251187:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45T:0.1089:0.183251187:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45F:0.56165:0.183251187:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79V:1.33255:0.109650038:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79R:4.66289:0.109650038:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79M:-0.50269:0.109650038:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79P:4.13879:0.109650038:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79Q:1.99682:0.109650038:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45P:0.63491:0.109650038:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45Y:0.59073:0.109650038:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45C:0.53656:0.109650038:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45A:0.59559:0.109650038:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45T:0.66071:0.109650038:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45F:0.42017:0.109650038:0.507999063 | 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