MitImpact is a collection of genomic, clinical and functional annotations for all nucleotide changes that cause non-synonymous substitutions in human mitochondrial protein coding genes
[12-07-2022] MitImpact 3D 3.0.8 released today, with minor fixes on the pathogenicity thresholds and the update of ClinVar and MITOMAP (July 2022). We have added HelixMTdb annotations.
[19-10-2021] MitImpact 3D 3.0.7 released today, with minor fixes to the search engine and some updates to ClinVar (October 2021), dbSNP (ver. 155), gnomAD (ver. 3.1), and MITOMAP (October update). Let's check the output legend.
[09-12-2020] Nucleic Acids Research just published our paper entitled MitImpact 3: modeling the residue interaction network of the Respiratory Chain subunits [link]