news model
license
| ~ | 10191 (T/G) | 10191 (T/A) | 10191 (T/C) | 10192 (C/G) | 10192 (C/A) | 10192 (C/T) |
|---|---|---|---|---|---|---|
| ~ | 10191 (Tcc/Gcc) | 10191 (Tcc/Acc) | 10191 (Tcc/Ccc) | 10192 (tCc/tGc) | 10192 (tCc/tAc) | 10192 (tCc/tTc) |
| Chr | chrM | chrM | chrM | chrM | chrM | chrM |
| Start | 10191 | 10191 | 10191 | 10192 | 10192 | 10192 |
| End | 10191 | 10191 | 10191 | 10192 | 10192 | 10192 |
| Ref | T | T | T | C | C | C |
| Alt | G | A | C | G | A | T |
| MitImpact id | MI.15246 | MI.15247 | MI.15248 | MI.15249 | MI.15250 | MI.15251 |
| Gene symbol | MT-ND3 | MT-ND3 | MT-ND3 | MT-ND3 | MT-ND3 | MT-ND3 |
| Respiratory Chain complex | I | I | I | I | I | I |
| Ensembl gene id | ENSG00000198840 | ENSG00000198840 | ENSG00000198840 | ENSG00000198840 | ENSG00000198840 | ENSG00000198840 |
| Ensembl protein id | ENSP00000355206 | ENSP00000355206 | ENSP00000355206 | ENSP00000355206 | ENSP00000355206 | ENSP00000355206 |
| Ensembl transcript id | ENST00000361227 | ENST00000361227 | ENST00000361227 | ENST00000361227 | ENST00000361227 | ENST00000361227 |
| Uniprot name | NU3M_HUMAN | NU3M_HUMAN | NU3M_HUMAN | NU3M_HUMAN | NU3M_HUMAN | NU3M_HUMAN |
| Uniprot id | P03897 | P03897 | P03897 | P03897 | P03897 | P03897 |
| Ncbi gene id | 4537 | 4537 | 4537 | 4537 | 4537 | 4537 |
| Ncbi protein id | YP_003024033.1 | YP_003024033.1 | YP_003024033.1 | YP_003024033.1 | YP_003024033.1 | YP_003024033.1 |
| Gene position | 133 | 133 | 133 | 134 | 134 | 134 |
| AA position | 45 | 45 | 45 | 45 | 45 | 45 |
| AA ref | S | S | S | S | S | S |
| AA alt | A | T | P | C | Y | F |
| Codon substitution | Tcc/Gcc | Tcc/Acc | Tcc/Ccc | tCc/tGc | tCc/tAc | tCc/tTc |
| PhyloP 100V | -0.1 | -0.1 | -0.1 | 3.6 | 3.6 | 3.6 |
| PhastCons 100V | 0.15 | 0.15 | 0.15 | 1 | 1 | 1 |
| PolyPhen2 | benign | benign | benign | possibly_damaging | benign | benign |
| PolyPhen2 score | 0.09 | 0.09 | 0.43 | 0.71 | 0 | 0 |
| SIFT | neutral | neutral | neutral | neutral | neutral | neutral |
| SIFT score | 0.79 | 0.6 | 0.3 | 0.08 | 0.17 | 0.14 |
| FatHmm | neutral | neutral | neutral | deleterious | neutral | deleterious |
| FatHmm score | -0.27 | -0.75 | -1.41 | -4.12 | -2.73 | -3.14 |
| FatHmmW | neutral | neutral | neutral | neutral | neutral | neutral |
| FatHmmW score | 0.91 | 0.9 | 0.85 | 0.82 | 0.84 | 0.84 |
| PROVEAN | neutral | neutral | deleterious | deleterious | deleterious | deleterious |
| PROVEAN score | -0.84 | -1.76 | -2.51 | -3.36 | -3.39 | -3.55 |
| MutationAssessor | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| MutationAssessor score | 2.38 | 2.13 | 2.88 | 3.23 | 2.54 | 2.6 |
| EFIN SP | neutral | damaging | damaging | neutral | neutral | neutral |
| EFIN SP score | 0.76 | 0.6 | 0.17 | 0.69 | 0.7 | 0.62 |
| EFIN HD | neutral | neutral | neutral | neutral | neutral | neutral |
| EFIN HD score | 0.81 | 0.65 | 0.35 | 0.43 | 0.58 | 0.54 |
| CADD | neutral | deleterious | deleterious | deleterious | deleterious | deleterious |
| CADD score | 1.74 | 1.82 | 2.31 | 3.22 | 2.2 | 2.24 |
| CADD phred | 14.63 | 15.08 | 18.21 | 22.7 | 17.48 | 17.75 |
| VEST pvalue | 0.3 | 0.33 | 0.12 | 0.11 | 0.09 | 0.11 |
| VEST FDR | 0.45 | 0.5 | 0.4 | 0.4 | 0.35 | 0.4 |
| PANTHER | neutral | neutral | neutral | disease | neutral | neutral |
| PANTHER score | 0.21 | 0.25 | 0.44 | 0.63 | 0.43 | 0.44 |
| PhD-SNP | neutral | neutral | disease | disease | disease | disease |
| PhD-SNP score | 0.31 | 0.35 | 0.76 | 0.6 | 0.59 | 0.65 |
| SNAP | disease | disease | disease | disease | disease | disease |
| SNAP score | 0.56 | 0.6 | 0.6 | 0.54 | 0.64 | 0.62 |
| Meta-SNP | neutral | neutral | disease | disease | disease | disease |
| Meta-SNP score | 0.4 | 0.42 | 0.69 | 0.66 | 0.69 | 0.7 |
| Meta-SNP RI | 2 | 2 | 4 | 3 | 4 | 4 |
| CAROL | neutral | neutral | neutral | neutral | neutral | neutral |
| CAROL score | 0.11 | 0.31 | 0.66 | 0.93 | 0.83 | 0.86 |
| Condel | deleterious | deleterious | neutral | neutral | deleterious | deleterious |
| Condel score | 0.85 | 0.76 | 0.44 | 0.19 | 0.59 | 0.57 |
| COVEC WMV | neutral | neutral | neutral | . | neutral | neutral |
| COVEC WMV score | -3 | -3 | -3 | 0 | -3 | -3 |
| MtoolBox | neutral | neutral | deleterious | deleterious | neutral | neutral |
| MtoolBox DS | 0.15 | 0.16 | 0.57 | 0.62 | 0.19 | 0.21 |
| PolyPhen2 transf | medium impact | medium impact | medium impact | low impact | medium impact | medium impact |
| PolyPhen2 transf score | 0.19 | 0.19 | -0.61 | -1.07 | 1.99 | 1.99 |
| SIFT_transf | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| SIFT transf score | 0.51 | 0.29 | -0.01 | -0.4 | -0.19 | -0.25 |
| MutationAssessor transf | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| MutationAssessor transf score | 1.07 | 0.84 | 1.53 | 1.85 | 1.22 | 1.28 |
| CHASM pvalue | 0.35 | 0.48 | 0.22 | 0.27 | 0.2 | 0.09 |
| CHASM FDR | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 |
| APOGEE | Likely-benign | Likely-benign | Likely-pathogenic | VUS | Likely-benign | VUS |
| APOGEE score | 0.1239408521159617 | 0.2071077973902883 | 0.8850098919877722 | 0.5969188669416251 | 0.2617029833182725 | 0.3151292513180633 |
| SNPDryad score | 0.1 | 0.13 | 0.6 | 0.56 | 0.06 | 0.54 |
| MutationTaster | polymorphism | polymorphism | disease_causing_automatic | polymorphism | polymorphism | polymorphism |
| MutationTaster score | 1 | 1 | 0 | 1 | 1 | 1 |
| DEOGEN2 score | 0.33 | 0.37 | 0.55 | 0.68 | 0.56 | 0.63 |
| Mitoclass.1 | neutral | neutral | neutral | neutral | neutral | neutral |
| dbSNP 155 id | . | . | rs267606890 | . | rs1556423776 | rs1556423776 |
| ClinVar October2021 Variation id | . | . | . | . | . | . |
| ClinVar October2021 CLNSIG | . | . | . | . | . | . |
| ClinVar October2021 CLNDN | . | . | . | . | . | . |
| ClinVar October2021 CLNDISDB | . | . | . | . | . | . |
| COSMIC 90 | . | . | . | . | . | . |
| MITOMAP Allele | . | . | T10191C | . | . | . |
| MITOMAP Disease Het/Hom | . | . | -/+ | . | . | . |
| MITOMAP Disease Clinical info | . | . | Leigh Disease / Leigh-like Disease / ESOC | . | . | . |
| MITOMAP Disease Status | . | . | Cfrm | . | . | . |
| MITOMAP Disease GenBank Freq | . | . | 0.000% | . | . | . |
| MITOMAP Disease GenBank Seqs | . | . | 0 (0) | . | . | . |
| MITOMAP Disease GenBank Curated refs | . | . | 27 | . | . | . |
| MITOMAP General GenBank Freq | 0.000% | . | . | . | 0.007% | 0.174% |
| MITOMAP General GenBank Seqs | 0 | . | . | . | 4 | 99 |
| MITOMAP General Curated refs | 1 | . | . | . | 1 | 9 |
| gnomAD 3.1 filter | PASS | PASS | npg | . | PASS | PASS |
| gnomAD 3.1 AC Homo | 2 | 1 | 0 | . | 12 | 81 |
| gnomAD 3.1 AC Het | 0 | 0 | 0 | . | 0 | 2 |
| gnomAD 3.1 AF Hom | 3.543963e-05 | 1.7719814e-05 | 0 | . | 0.00021263777 | 0.0014354321 |
| gnomAD 3.1 AF Het | 0 | 0 | 0 | . | 0 | 3.544277e-05 |
| gnomAD 3.1 AN | 56434 | 56434 | 56433 | . | 56434 | 56429 |
| HelixMTdb AC Hom | 2 | . | . | . | 16 | 318 |
| HelixMTdb AF Hom | 1.0204967e-05 | . | . | . | 8.163974e-05 | 0.0016225898 |
| HelixMTdb AC Het | 0 | . | . | . | 0 | 5 |
| HelixMTdb AF Het | 0 | . | . | . | 0 | 2.5512418e-05 |
| HelixMTdb mean ARF | . | . | . | . | . | 0.43853 | HelixMTdb max ARF | . | . | . | . | . | 0.88235 |
| EVmutation | MT-ND3_45S|47A:0.28422;53M:0.197548;77W:0.189385;67L:0.153054;46P:0.148367;63L:0.140246;49V:0.127445;70A:0.110601;69I:0.089183;99A:0.088252;106W:0.080069;83N:0.078717;89M:0.071885;97I:0.069759 | MT-ND3_45S|47A:0.28422;53M:0.197548;77W:0.189385;67L:0.153054;46P:0.148367;63L:0.140246;49V:0.127445;70A:0.110601;69I:0.089183;99A:0.088252;106W:0.080069;83N:0.078717;89M:0.071885;97I:0.069759 | MT-ND3_45S|47A:0.28422;53M:0.197548;77W:0.189385;67L:0.153054;46P:0.148367;63L:0.140246;49V:0.127445;70A:0.110601;69I:0.089183;99A:0.088252;106W:0.080069;83N:0.078717;89M:0.071885;97I:0.069759 | MT-ND3_45S|47A:0.28422;53M:0.197548;77W:0.189385;67L:0.153054;46P:0.148367;63L:0.140246;49V:0.127445;70A:0.110601;69I:0.089183;99A:0.088252;106W:0.080069;83N:0.078717;89M:0.071885;97I:0.069759 | MT-ND3_45S|47A:0.28422;53M:0.197548;77W:0.189385;67L:0.153054;46P:0.148367;63L:0.140246;49V:0.127445;70A:0.110601;69I:0.089183;99A:0.088252;106W:0.080069;83N:0.078717;89M:0.071885;97I:0.069759 | MT-ND3_45S|47A:0.28422;53M:0.197548;77W:0.189385;67L:0.153054;46P:0.148367;63L:0.140246;49V:0.127445;70A:0.110601;69I:0.089183;99A:0.088252;106W:0.080069;83N:0.078717;89M:0.071885;97I:0.069759 |
| Site A InterP | ND3_45 | ND3_45 | ND3_45 | ND3_45 | ND3_45 | ND3_45 |
| Site B InterP | ND1_231;ND1_128;ND1_46;ND1_156;ND2_4;ND2_60;ND4_198;ND4_202;ND4_416;ND4L_57;ND4L_67;ND4L_27;ND5_497;ND5_414;ND1_248;ND1_67;ND1_126;ND1_71;ND1_93;ND1_76;ND1_27;ND1_84;ND1_276;ND1_249;ND1_163;ND1_229;ND1_85;ND1_62;ND1_301;ND1_64;ND1_251;ND1_79;ND2_166;ND2_6;ND2_89;ND2_265;ND2_241;ND2_239;ND2_276;ND2_78;ND2_10;ND2_76;ND2_94;ND4_442;ND4_411;ND4_49;ND4_248;ND4_38;ND4_4;ND4_438;ND4_426;ND4_85;ND4_56;ND4_140;ND4_27;ND4_54;ND4_99;ND4_444;ND4L_80;ND4L_54;ND4L_48;ND4L_91;ND4L_58;ND4L_57;ND4L_28;ND4L_38;ND5_193;ND5_572;ND5_480;ND5_202;ND5_160;ND5_518;ND5_428;ND5_41;ND5_75;ND5_420;ND5_492;ND5_583;ND5_169;ND5_426;ND6_41;ND6_17;ND6_87;ND6_135;ND6_21;ND6_86;ND6_5 | ND1_231;ND1_128;ND1_46;ND1_156;ND2_4;ND2_60;ND4_198;ND4_202;ND4_416;ND4L_57;ND4L_67;ND4L_27;ND5_497;ND5_414;ND1_248;ND1_67;ND1_126;ND1_71;ND1_93;ND1_76;ND1_27;ND1_84;ND1_276;ND1_249;ND1_163;ND1_229;ND1_85;ND1_62;ND1_301;ND1_64;ND1_251;ND1_79;ND2_166;ND2_6;ND2_89;ND2_265;ND2_241;ND2_239;ND2_276;ND2_78;ND2_10;ND2_76;ND2_94;ND4_442;ND4_411;ND4_49;ND4_248;ND4_38;ND4_4;ND4_438;ND4_426;ND4_85;ND4_56;ND4_140;ND4_27;ND4_54;ND4_99;ND4_444;ND4L_80;ND4L_54;ND4L_48;ND4L_91;ND4L_58;ND4L_57;ND4L_28;ND4L_38;ND5_193;ND5_572;ND5_480;ND5_202;ND5_160;ND5_518;ND5_428;ND5_41;ND5_75;ND5_420;ND5_492;ND5_583;ND5_169;ND5_426;ND6_41;ND6_17;ND6_87;ND6_135;ND6_21;ND6_86;ND6_5 | ND1_231;ND1_128;ND1_46;ND1_156;ND2_4;ND2_60;ND4_198;ND4_202;ND4_416;ND4L_57;ND4L_67;ND4L_27;ND5_497;ND5_414;ND1_248;ND1_67;ND1_126;ND1_71;ND1_93;ND1_76;ND1_27;ND1_84;ND1_276;ND1_249;ND1_163;ND1_229;ND1_85;ND1_62;ND1_301;ND1_64;ND1_251;ND1_79;ND2_166;ND2_6;ND2_89;ND2_265;ND2_241;ND2_239;ND2_276;ND2_78;ND2_10;ND2_76;ND2_94;ND4_442;ND4_411;ND4_49;ND4_248;ND4_38;ND4_4;ND4_438;ND4_426;ND4_85;ND4_56;ND4_140;ND4_27;ND4_54;ND4_99;ND4_444;ND4L_80;ND4L_54;ND4L_48;ND4L_91;ND4L_58;ND4L_57;ND4L_28;ND4L_38;ND5_193;ND5_572;ND5_480;ND5_202;ND5_160;ND5_518;ND5_428;ND5_41;ND5_75;ND5_420;ND5_492;ND5_583;ND5_169;ND5_426;ND6_41;ND6_17;ND6_87;ND6_135;ND6_21;ND6_86;ND6_5 | ND1_231;ND1_128;ND1_46;ND1_156;ND2_4;ND2_60;ND4_198;ND4_202;ND4_416;ND4L_57;ND4L_67;ND4L_27;ND5_497;ND5_414;ND1_248;ND1_67;ND1_126;ND1_71;ND1_93;ND1_76;ND1_27;ND1_84;ND1_276;ND1_249;ND1_163;ND1_229;ND1_85;ND1_62;ND1_301;ND1_64;ND1_251;ND1_79;ND2_166;ND2_6;ND2_89;ND2_265;ND2_241;ND2_239;ND2_276;ND2_78;ND2_10;ND2_76;ND2_94;ND4_442;ND4_411;ND4_49;ND4_248;ND4_38;ND4_4;ND4_438;ND4_426;ND4_85;ND4_56;ND4_140;ND4_27;ND4_54;ND4_99;ND4_444;ND4L_80;ND4L_54;ND4L_48;ND4L_91;ND4L_58;ND4L_57;ND4L_28;ND4L_38;ND5_193;ND5_572;ND5_480;ND5_202;ND5_160;ND5_518;ND5_428;ND5_41;ND5_75;ND5_420;ND5_492;ND5_583;ND5_169;ND5_426;ND6_41;ND6_17;ND6_87;ND6_135;ND6_21;ND6_86;ND6_5 | ND1_231;ND1_128;ND1_46;ND1_156;ND2_4;ND2_60;ND4_198;ND4_202;ND4_416;ND4L_57;ND4L_67;ND4L_27;ND5_497;ND5_414;ND1_248;ND1_67;ND1_126;ND1_71;ND1_93;ND1_76;ND1_27;ND1_84;ND1_276;ND1_249;ND1_163;ND1_229;ND1_85;ND1_62;ND1_301;ND1_64;ND1_251;ND1_79;ND2_166;ND2_6;ND2_89;ND2_265;ND2_241;ND2_239;ND2_276;ND2_78;ND2_10;ND2_76;ND2_94;ND4_442;ND4_411;ND4_49;ND4_248;ND4_38;ND4_4;ND4_438;ND4_426;ND4_85;ND4_56;ND4_140;ND4_27;ND4_54;ND4_99;ND4_444;ND4L_80;ND4L_54;ND4L_48;ND4L_91;ND4L_58;ND4L_57;ND4L_28;ND4L_38;ND5_193;ND5_572;ND5_480;ND5_202;ND5_160;ND5_518;ND5_428;ND5_41;ND5_75;ND5_420;ND5_492;ND5_583;ND5_169;ND5_426;ND6_41;ND6_17;ND6_87;ND6_135;ND6_21;ND6_86;ND6_5 | ND1_231;ND1_128;ND1_46;ND1_156;ND2_4;ND2_60;ND4_198;ND4_202;ND4_416;ND4L_57;ND4L_67;ND4L_27;ND5_497;ND5_414;ND1_248;ND1_67;ND1_126;ND1_71;ND1_93;ND1_76;ND1_27;ND1_84;ND1_276;ND1_249;ND1_163;ND1_229;ND1_85;ND1_62;ND1_301;ND1_64;ND1_251;ND1_79;ND2_166;ND2_6;ND2_89;ND2_265;ND2_241;ND2_239;ND2_276;ND2_78;ND2_10;ND2_76;ND2_94;ND4_442;ND4_411;ND4_49;ND4_248;ND4_38;ND4_4;ND4_438;ND4_426;ND4_85;ND4_56;ND4_140;ND4_27;ND4_54;ND4_99;ND4_444;ND4L_80;ND4L_54;ND4L_48;ND4L_91;ND4L_58;ND4L_57;ND4L_28;ND4L_38;ND5_193;ND5_572;ND5_480;ND5_202;ND5_160;ND5_518;ND5_428;ND5_41;ND5_75;ND5_420;ND5_492;ND5_583;ND5_169;ND5_426;ND6_41;ND6_17;ND6_87;ND6_135;ND6_21;ND6_86;ND6_5 |
| Covariation Score InterP | mfDCA_43.06;mfDCA_38.66;mfDCA_33.28;mfDCA_32.98;mfDCA_37.45;mfDCA_27.97;mfDCA_37.96;mfDCA_22.41;mfDCA_21.64;cMI_14.42049;mfDCA_34.27;mfDCA_26.86;mfDCA_79.1;mfDCA_31.92;cMI_49.89251;cMI_42.92984;cMI_41.72575;cMI_41.35901;cMI_39.83745;cMI_39.80877;cMI_39.28621;cMI_39.25341;cMI_38.90435;cMI_37.23441;cMI_37.10332;cMI_35.91475;cMI_35.72486;cMI_34.76365;cMI_34.26473;cMI_32.72981;cMI_31.32613;cMI_30.89244;cMI_22.94652;cMI_22.92951;cMI_22.78181;cMI_22.0794;cMI_21.36701;cMI_21.16552;cMI_19.74607;cMI_19.27132;cMI_18.72378;cMI_18.45074;cMI_18.01385;cMI_45.83789;cMI_44.22917;cMI_36.96359;cMI_36.7885;cMI_36.36468;cMI_34.82834;cMI_34.44059;cMI_34.16881;cMI_34.00615;cMI_33.7583;cMI_32.86419;cMI_32.3116;cMI_32.27547;cMI_31.86143;cMI_31.70077;cMI_30.23993;cMI_22.23638;cMI_19.73961;cMI_19.16892;cMI_15.51931;cMI_14.42049;cMI_12.72224;cMI_12.48772;cMI_45.56686;cMI_39.36692;cMI_39.2702;cMI_39.21392;cMI_37.50221;cMI_37.33206;cMI_37.03395;cMI_36.14669;cMI_36.0487;cMI_36.01114;cMI_35.29195;cMI_33.17587;cMI_32.8188;cMI_31.61218;cMI_19.13398;cMI_17.85636;cMI_17.52418;cMI_16.19448;cMI_14.52225;cMI_13.83411;cMI_13.57866 | mfDCA_43.06;mfDCA_38.66;mfDCA_33.28;mfDCA_32.98;mfDCA_37.45;mfDCA_27.97;mfDCA_37.96;mfDCA_22.41;mfDCA_21.64;cMI_14.42049;mfDCA_34.27;mfDCA_26.86;mfDCA_79.1;mfDCA_31.92;cMI_49.89251;cMI_42.92984;cMI_41.72575;cMI_41.35901;cMI_39.83745;cMI_39.80877;cMI_39.28621;cMI_39.25341;cMI_38.90435;cMI_37.23441;cMI_37.10332;cMI_35.91475;cMI_35.72486;cMI_34.76365;cMI_34.26473;cMI_32.72981;cMI_31.32613;cMI_30.89244;cMI_22.94652;cMI_22.92951;cMI_22.78181;cMI_22.0794;cMI_21.36701;cMI_21.16552;cMI_19.74607;cMI_19.27132;cMI_18.72378;cMI_18.45074;cMI_18.01385;cMI_45.83789;cMI_44.22917;cMI_36.96359;cMI_36.7885;cMI_36.36468;cMI_34.82834;cMI_34.44059;cMI_34.16881;cMI_34.00615;cMI_33.7583;cMI_32.86419;cMI_32.3116;cMI_32.27547;cMI_31.86143;cMI_31.70077;cMI_30.23993;cMI_22.23638;cMI_19.73961;cMI_19.16892;cMI_15.51931;cMI_14.42049;cMI_12.72224;cMI_12.48772;cMI_45.56686;cMI_39.36692;cMI_39.2702;cMI_39.21392;cMI_37.50221;cMI_37.33206;cMI_37.03395;cMI_36.14669;cMI_36.0487;cMI_36.01114;cMI_35.29195;cMI_33.17587;cMI_32.8188;cMI_31.61218;cMI_19.13398;cMI_17.85636;cMI_17.52418;cMI_16.19448;cMI_14.52225;cMI_13.83411;cMI_13.57866 | mfDCA_43.06;mfDCA_38.66;mfDCA_33.28;mfDCA_32.98;mfDCA_37.45;mfDCA_27.97;mfDCA_37.96;mfDCA_22.41;mfDCA_21.64;cMI_14.42049;mfDCA_34.27;mfDCA_26.86;mfDCA_79.1;mfDCA_31.92;cMI_49.89251;cMI_42.92984;cMI_41.72575;cMI_41.35901;cMI_39.83745;cMI_39.80877;cMI_39.28621;cMI_39.25341;cMI_38.90435;cMI_37.23441;cMI_37.10332;cMI_35.91475;cMI_35.72486;cMI_34.76365;cMI_34.26473;cMI_32.72981;cMI_31.32613;cMI_30.89244;cMI_22.94652;cMI_22.92951;cMI_22.78181;cMI_22.0794;cMI_21.36701;cMI_21.16552;cMI_19.74607;cMI_19.27132;cMI_18.72378;cMI_18.45074;cMI_18.01385;cMI_45.83789;cMI_44.22917;cMI_36.96359;cMI_36.7885;cMI_36.36468;cMI_34.82834;cMI_34.44059;cMI_34.16881;cMI_34.00615;cMI_33.7583;cMI_32.86419;cMI_32.3116;cMI_32.27547;cMI_31.86143;cMI_31.70077;cMI_30.23993;cMI_22.23638;cMI_19.73961;cMI_19.16892;cMI_15.51931;cMI_14.42049;cMI_12.72224;cMI_12.48772;cMI_45.56686;cMI_39.36692;cMI_39.2702;cMI_39.21392;cMI_37.50221;cMI_37.33206;cMI_37.03395;cMI_36.14669;cMI_36.0487;cMI_36.01114;cMI_35.29195;cMI_33.17587;cMI_32.8188;cMI_31.61218;cMI_19.13398;cMI_17.85636;cMI_17.52418;cMI_16.19448;cMI_14.52225;cMI_13.83411;cMI_13.57866 | mfDCA_43.06;mfDCA_38.66;mfDCA_33.28;mfDCA_32.98;mfDCA_37.45;mfDCA_27.97;mfDCA_37.96;mfDCA_22.41;mfDCA_21.64;cMI_14.42049;mfDCA_34.27;mfDCA_26.86;mfDCA_79.1;mfDCA_31.92;cMI_49.89251;cMI_42.92984;cMI_41.72575;cMI_41.35901;cMI_39.83745;cMI_39.80877;cMI_39.28621;cMI_39.25341;cMI_38.90435;cMI_37.23441;cMI_37.10332;cMI_35.91475;cMI_35.72486;cMI_34.76365;cMI_34.26473;cMI_32.72981;cMI_31.32613;cMI_30.89244;cMI_22.94652;cMI_22.92951;cMI_22.78181;cMI_22.0794;cMI_21.36701;cMI_21.16552;cMI_19.74607;cMI_19.27132;cMI_18.72378;cMI_18.45074;cMI_18.01385;cMI_45.83789;cMI_44.22917;cMI_36.96359;cMI_36.7885;cMI_36.36468;cMI_34.82834;cMI_34.44059;cMI_34.16881;cMI_34.00615;cMI_33.7583;cMI_32.86419;cMI_32.3116;cMI_32.27547;cMI_31.86143;cMI_31.70077;cMI_30.23993;cMI_22.23638;cMI_19.73961;cMI_19.16892;cMI_15.51931;cMI_14.42049;cMI_12.72224;cMI_12.48772;cMI_45.56686;cMI_39.36692;cMI_39.2702;cMI_39.21392;cMI_37.50221;cMI_37.33206;cMI_37.03395;cMI_36.14669;cMI_36.0487;cMI_36.01114;cMI_35.29195;cMI_33.17587;cMI_32.8188;cMI_31.61218;cMI_19.13398;cMI_17.85636;cMI_17.52418;cMI_16.19448;cMI_14.52225;cMI_13.83411;cMI_13.57866 | mfDCA_43.06;mfDCA_38.66;mfDCA_33.28;mfDCA_32.98;mfDCA_37.45;mfDCA_27.97;mfDCA_37.96;mfDCA_22.41;mfDCA_21.64;cMI_14.42049;mfDCA_34.27;mfDCA_26.86;mfDCA_79.1;mfDCA_31.92;cMI_49.89251;cMI_42.92984;cMI_41.72575;cMI_41.35901;cMI_39.83745;cMI_39.80877;cMI_39.28621;cMI_39.25341;cMI_38.90435;cMI_37.23441;cMI_37.10332;cMI_35.91475;cMI_35.72486;cMI_34.76365;cMI_34.26473;cMI_32.72981;cMI_31.32613;cMI_30.89244;cMI_22.94652;cMI_22.92951;cMI_22.78181;cMI_22.0794;cMI_21.36701;cMI_21.16552;cMI_19.74607;cMI_19.27132;cMI_18.72378;cMI_18.45074;cMI_18.01385;cMI_45.83789;cMI_44.22917;cMI_36.96359;cMI_36.7885;cMI_36.36468;cMI_34.82834;cMI_34.44059;cMI_34.16881;cMI_34.00615;cMI_33.7583;cMI_32.86419;cMI_32.3116;cMI_32.27547;cMI_31.86143;cMI_31.70077;cMI_30.23993;cMI_22.23638;cMI_19.73961;cMI_19.16892;cMI_15.51931;cMI_14.42049;cMI_12.72224;cMI_12.48772;cMI_45.56686;cMI_39.36692;cMI_39.2702;cMI_39.21392;cMI_37.50221;cMI_37.33206;cMI_37.03395;cMI_36.14669;cMI_36.0487;cMI_36.01114;cMI_35.29195;cMI_33.17587;cMI_32.8188;cMI_31.61218;cMI_19.13398;cMI_17.85636;cMI_17.52418;cMI_16.19448;cMI_14.52225;cMI_13.83411;cMI_13.57866 | mfDCA_43.06;mfDCA_38.66;mfDCA_33.28;mfDCA_32.98;mfDCA_37.45;mfDCA_27.97;mfDCA_37.96;mfDCA_22.41;mfDCA_21.64;cMI_14.42049;mfDCA_34.27;mfDCA_26.86;mfDCA_79.1;mfDCA_31.92;cMI_49.89251;cMI_42.92984;cMI_41.72575;cMI_41.35901;cMI_39.83745;cMI_39.80877;cMI_39.28621;cMI_39.25341;cMI_38.90435;cMI_37.23441;cMI_37.10332;cMI_35.91475;cMI_35.72486;cMI_34.76365;cMI_34.26473;cMI_32.72981;cMI_31.32613;cMI_30.89244;cMI_22.94652;cMI_22.92951;cMI_22.78181;cMI_22.0794;cMI_21.36701;cMI_21.16552;cMI_19.74607;cMI_19.27132;cMI_18.72378;cMI_18.45074;cMI_18.01385;cMI_45.83789;cMI_44.22917;cMI_36.96359;cMI_36.7885;cMI_36.36468;cMI_34.82834;cMI_34.44059;cMI_34.16881;cMI_34.00615;cMI_33.7583;cMI_32.86419;cMI_32.3116;cMI_32.27547;cMI_31.86143;cMI_31.70077;cMI_30.23993;cMI_22.23638;cMI_19.73961;cMI_19.16892;cMI_15.51931;cMI_14.42049;cMI_12.72224;cMI_12.48772;cMI_45.56686;cMI_39.36692;cMI_39.2702;cMI_39.21392;cMI_37.50221;cMI_37.33206;cMI_37.03395;cMI_36.14669;cMI_36.0487;cMI_36.01114;cMI_35.29195;cMI_33.17587;cMI_32.8188;cMI_31.61218;cMI_19.13398;cMI_17.85636;cMI_17.52418;cMI_16.19448;cMI_14.52225;cMI_13.83411;cMI_13.57866 |
| Site A IntraP | ND3_45 | ND3_45 | ND3_45 | ND3_45 | ND3_45 | ND3_45 |
| Site B IntraP | ND3_35;ND3_18;ND3_88;ND3_8;ND3_97;ND3_89;ND3_4;ND3_49;ND3_21;ND3_79;ND3_29;ND3_19;ND3_44;ND3_15;ND3_112;ND3_91;ND3_35;ND3_88;ND3_89;ND3_19;ND3_44;ND3_21;ND3_107 | ND3_35;ND3_18;ND3_88;ND3_8;ND3_97;ND3_89;ND3_4;ND3_49;ND3_21;ND3_79;ND3_29;ND3_19;ND3_44;ND3_15;ND3_112;ND3_91;ND3_35;ND3_88;ND3_89;ND3_19;ND3_44;ND3_21;ND3_107 | ND3_35;ND3_18;ND3_88;ND3_8;ND3_97;ND3_89;ND3_4;ND3_49;ND3_21;ND3_79;ND3_29;ND3_19;ND3_44;ND3_15;ND3_112;ND3_91;ND3_35;ND3_88;ND3_89;ND3_19;ND3_44;ND3_21;ND3_107 | ND3_35;ND3_18;ND3_88;ND3_8;ND3_97;ND3_89;ND3_4;ND3_49;ND3_21;ND3_79;ND3_29;ND3_19;ND3_44;ND3_15;ND3_112;ND3_91;ND3_35;ND3_88;ND3_89;ND3_19;ND3_44;ND3_21;ND3_107 | ND3_35;ND3_18;ND3_88;ND3_8;ND3_97;ND3_89;ND3_4;ND3_49;ND3_21;ND3_79;ND3_29;ND3_19;ND3_44;ND3_15;ND3_112;ND3_91;ND3_35;ND3_88;ND3_89;ND3_19;ND3_44;ND3_21;ND3_107 | ND3_35;ND3_18;ND3_88;ND3_8;ND3_97;ND3_89;ND3_4;ND3_49;ND3_21;ND3_79;ND3_29;ND3_19;ND3_44;ND3_15;ND3_112;ND3_91;ND3_35;ND3_88;ND3_89;ND3_19;ND3_44;ND3_21;ND3_107 |
| Covariation Score IntraP | mfDCA_24.6929;cMI_18.130184;mfDCA_22.1031;cMI_15.679218;cMI_15.674643;mfDCA_18.5493;cMI_15.140093;cMI_12.779061;mfDCA_16.7255;cMI_12.428753;cMI_12.024128;mfDCA_18.0094;mfDCA_17.102;cMI_10.232872;cMI_10.168221;cMI_9.709738;mfDCA_24.6929;mfDCA_22.1031;mfDCA_18.5493;mfDCA_18.0094;mfDCA_17.102;mfDCA_16.7255;mfDCA_15.438 | mfDCA_24.6929;cMI_18.130184;mfDCA_22.1031;cMI_15.679218;cMI_15.674643;mfDCA_18.5493;cMI_15.140093;cMI_12.779061;mfDCA_16.7255;cMI_12.428753;cMI_12.024128;mfDCA_18.0094;mfDCA_17.102;cMI_10.232872;cMI_10.168221;cMI_9.709738;mfDCA_24.6929;mfDCA_22.1031;mfDCA_18.5493;mfDCA_18.0094;mfDCA_17.102;mfDCA_16.7255;mfDCA_15.438 | mfDCA_24.6929;cMI_18.130184;mfDCA_22.1031;cMI_15.679218;cMI_15.674643;mfDCA_18.5493;cMI_15.140093;cMI_12.779061;mfDCA_16.7255;cMI_12.428753;cMI_12.024128;mfDCA_18.0094;mfDCA_17.102;cMI_10.232872;cMI_10.168221;cMI_9.709738;mfDCA_24.6929;mfDCA_22.1031;mfDCA_18.5493;mfDCA_18.0094;mfDCA_17.102;mfDCA_16.7255;mfDCA_15.438 | mfDCA_24.6929;cMI_18.130184;mfDCA_22.1031;cMI_15.679218;cMI_15.674643;mfDCA_18.5493;cMI_15.140093;cMI_12.779061;mfDCA_16.7255;cMI_12.428753;cMI_12.024128;mfDCA_18.0094;mfDCA_17.102;cMI_10.232872;cMI_10.168221;cMI_9.709738;mfDCA_24.6929;mfDCA_22.1031;mfDCA_18.5493;mfDCA_18.0094;mfDCA_17.102;mfDCA_16.7255;mfDCA_15.438 | mfDCA_24.6929;cMI_18.130184;mfDCA_22.1031;cMI_15.679218;cMI_15.674643;mfDCA_18.5493;cMI_15.140093;cMI_12.779061;mfDCA_16.7255;cMI_12.428753;cMI_12.024128;mfDCA_18.0094;mfDCA_17.102;cMI_10.232872;cMI_10.168221;cMI_9.709738;mfDCA_24.6929;mfDCA_22.1031;mfDCA_18.5493;mfDCA_18.0094;mfDCA_17.102;mfDCA_16.7255;mfDCA_15.438 | mfDCA_24.6929;cMI_18.130184;mfDCA_22.1031;cMI_15.679218;cMI_15.674643;mfDCA_18.5493;cMI_15.140093;cMI_12.779061;mfDCA_16.7255;cMI_12.428753;cMI_12.024128;mfDCA_18.0094;mfDCA_17.102;cMI_10.232872;cMI_10.168221;cMI_9.709738;mfDCA_24.6929;mfDCA_22.1031;mfDCA_18.5493;mfDCA_18.0094;mfDCA_17.102;mfDCA_16.7255;mfDCA_15.438 |
| CPD AA ref | . | . | . | . | . | . |
| CPD AA alt | . | . | . | . | . | . |
| CPD Aln pos | . | . | . | . | . | . |
| CPD Frequency | . | . | . | . | . | . |
| CPD Species name | . | . | . | . | . | . |
| CPD RefSeq Protein ID | . | . | . | . | . | . |
| CPD Ncbi Taxon id | . | . | . | . | . | . |
| DDG intra | MT-ND3:S45A:L107Q:1.86944:0.898719:0.964638;MT-ND3:S45A:L107V:2.4996:0.898719:1.58272;MT-ND3:S45A:L107M:0.715066:0.898719:-0.186263;MT-ND3:S45A:L107P:5.69195:0.898719:4.56316;MT-ND3:S45A:L107R:1.54806:0.898719:0.654602;MT-ND3:S45A:D112N:0.927985:0.898719:-0.0131052;MT-ND3:S45A:D112Y:0.523376:0.898719:-0.433469;MT-ND3:S45A:D112A:0.520717:0.898719:-0.418179;MT-ND3:S45A:D112G:1.3301:0.898719:0.414236;MT-ND3:S45A:D112E:0.712251:0.898719:-0.258161;MT-ND3:S45A:D112H:1.01463:0.898719:0.0340833;MT-ND3:S45A:D112V:1.12683:0.898719:0.179616;MT-ND3:S45A:V49G:1.91344:0.898719:0.888794;MT-ND3:S45A:V49A:1.18917:0.898719:0.193963;MT-ND3:S45A:V49I:1.04652:0.898719:-0.482548;MT-ND3:S45A:V49D:0.361223:0.898719:-0.607087;MT-ND3:S45A:V49F:0.363601:0.898719:-0.639481;MT-ND3:S45A:V49L:0.656181:0.898719:-0.289594;MT-ND3:S45A:L79Q:1.61103:0.898719:0.615227;MT-ND3:S45A:L79M:0.765146:0.898719:-0.174798;MT-ND3:S45A:L79P:4.64388:0.898719:3.64483;MT-ND3:S45A:L79V:2.59329:0.898719:1.69291;MT-ND3:S45A:L79R:1.91579:0.898719:1.00907;MT-ND3:S45A:G29R:1.02808:0.898719:0.0789448;MT-ND3:S45A:G29S:0.984365:0.898719:0.061955;MT-ND3:S45A:G29C:1.2321:0.898719:0.290877;MT-ND3:S45A:G29D:1.16518:0.898719:0.254493;MT-ND3:S45A:G29V:1.44128:0.898719:0.518345;MT-ND3:S45A:G29A:1.08002:0.898719:0.171581;MT-ND3:S45A:T35I:0.400209:0.898719:-0.515883;MT-ND3:S45A:T35P:1.37802:0.898719:0.442305;MT-ND3:S45A:T35S:1.32111:0.898719:0.233842;MT-ND3:S45A:T35N:1.22877:0.898719:0.309927;MT-ND3:S45A:T35A:1.00227:0.898719:0.0855016;MT-ND3:S45A:M44L:1.1635:0.898719:0.360285;MT-ND3:S45A:M44I:1.172:0.898719:0.322536;MT-ND3:S45A:M44K:1.1209:0.898719:0.331748;MT-ND3:S45A:M44V:1.30387:0.898719:0.489564;MT-ND3:S45A:M44T:1.30656:0.898719:0.4131;MT-ND3:S45A:A4D:1.05147:0.898719:0.190562;MT-ND3:S45A:A4P:-0.509629:0.898719:-1.526;MT-ND3:S45A:A4G:2.00368:0.898719:1.08914;MT-ND3:S45A:A4S:1.82332:0.898719:0.901348;MT-ND3:S45A:A4V:1.29706:0.898719:0.176529;MT-ND3:S45A:A4T:2.66952:0.898719:1.29799 | MT-ND3:S45T:L107M:-0.381736:-0.193334:-0.186263;MT-ND3:S45T:L107R:0.471732:-0.193334:0.654602;MT-ND3:S45T:L107P:4.50682:-0.193334:4.56316;MT-ND3:S45T:L107V:1.38096:-0.193334:1.58272;MT-ND3:S45T:L107Q:0.786723:-0.193334:0.964638;MT-ND3:S45T:D112V:-0.0198059:-0.193334:0.179616;MT-ND3:S45T:D112E:-0.445382:-0.193334:-0.258161;MT-ND3:S45T:D112G:0.202581:-0.193334:0.414236;MT-ND3:S45T:D112A:-0.626307:-0.193334:-0.418179;MT-ND3:S45T:D112Y:-0.636864:-0.193334:-0.433469;MT-ND3:S45T:D112N:-0.201313:-0.193334:-0.0131052;MT-ND3:S45T:D112H:-0.145536:-0.193334:0.0340833;MT-ND3:S45T:V49F:-0.827647:-0.193334:-0.639481;MT-ND3:S45T:V49D:-0.82733:-0.193334:-0.607087;MT-ND3:S45T:V49L:-0.356219:-0.193334:-0.289594;MT-ND3:S45T:V49G:0.795547:-0.193334:0.888794;MT-ND3:S45T:V49I:-0.547249:-0.193334:-0.482548;MT-ND3:S45T:V49A:0.303211:-0.193334:0.193963;MT-ND3:S45T:L79P:3.45752:-0.193334:3.64483;MT-ND3:S45T:L79M:-0.355915:-0.193334:-0.174798;MT-ND3:S45T:L79Q:0.443294:-0.193334:0.615227;MT-ND3:S45T:L79V:1.49783:-0.193334:1.69291;MT-ND3:S45T:L79R:0.819644:-0.193334:1.00907;MT-ND3:S45T:G29C:0.100006:-0.193334:0.290877;MT-ND3:S45T:G29D:0.0640916:-0.193334:0.254493;MT-ND3:S45T:G29S:-0.130535:-0.193334:0.061955;MT-ND3:S45T:G29A:-0.0189741:-0.193334:0.171581;MT-ND3:S45T:G29R:-0.103894:-0.193334:0.0789448;MT-ND3:S45T:G29V:0.325636:-0.193334:0.518345;MT-ND3:S45T:T35A:-0.102041:-0.193334:0.0855016;MT-ND3:S45T:T35S:0.0445892:-0.193334:0.233842;MT-ND3:S45T:T35N:0.146617:-0.193334:0.309927;MT-ND3:S45T:T35P:0.248048:-0.193334:0.442305;MT-ND3:S45T:T35I:-0.708227:-0.193334:-0.515883;MT-ND3:S45T:M44K:0.114574:-0.193334:0.331748;MT-ND3:S45T:M44T:0.268254:-0.193334:0.4131;MT-ND3:S45T:M44V:0.340112:-0.193334:0.489564;MT-ND3:S45T:M44I:0.140842:-0.193334:0.322536;MT-ND3:S45T:M44L:0.0106605:-0.193334:0.360285;MT-ND3:S45T:A4S:0.708495:-0.193334:0.901348;MT-ND3:S45T:A4G:0.900125:-0.193334:1.08914;MT-ND3:S45T:A4P:-1.64918:-0.193334:-1.526;MT-ND3:S45T:A4D:0.0231006:-0.193334:0.190562;MT-ND3:S45T:A4V:-0.0981623:-0.193334:0.176529;MT-ND3:S45T:A4T:1.44737:-0.193334:1.29799 | MT-ND3:S45P:L107Q:5.1219:4.1339:0.964638;MT-ND3:S45P:L107R:4.80834:4.1339:0.654602;MT-ND3:S45P:L107P:8.85061:4.1339:4.56316;MT-ND3:S45P:L107V:5.75541:4.1339:1.58272;MT-ND3:S45P:L107M:3.93827:4.1339:-0.186263;MT-ND3:S45P:D112H:4.20228:4.1339:0.0340833;MT-ND3:S45P:D112Y:3.77103:4.1339:-0.433469;MT-ND3:S45P:D112N:4.16016:4.1339:-0.0131052;MT-ND3:S45P:D112E:3.96989:4.1339:-0.258161;MT-ND3:S45P:D112G:4.55127:4.1339:0.414236;MT-ND3:S45P:D112V:4.3272:4.1339:0.179616;MT-ND3:S45P:D112A:3.66153:4.1339:-0.418179;MT-ND3:S45P:V49G:5.06697:4.1339:0.888794;MT-ND3:S45P:V49A:4.39278:4.1339:0.193963;MT-ND3:S45P:V49L:3.81485:4.1339:-0.289594;MT-ND3:S45P:V49D:3.5169:4.1339:-0.607087;MT-ND3:S45P:V49F:3.48098:4.1339:-0.639481;MT-ND3:S45P:V49I:4.28611:4.1339:-0.482548;MT-ND3:S45P:L79Q:4.85566:4.1339:0.615227;MT-ND3:S45P:L79R:5.1586:4.1339:1.00907;MT-ND3:S45P:L79M:3.98456:4.1339:-0.174798;MT-ND3:S45P:L79V:5.84676:4.1339:1.69291;MT-ND3:S45P:L79P:7.80779:4.1339:3.64483;MT-ND3:S45P:G29D:4.40541:4.1339:0.254493;MT-ND3:S45P:G29A:4.25797:4.1339:0.171581;MT-ND3:S45P:G29C:4.43954:4.1339:0.290877;MT-ND3:S45P:G29S:4.20152:4.1339:0.061955;MT-ND3:S45P:G29V:4.69077:4.1339:0.518345;MT-ND3:S45P:G29R:4.21889:4.1339:0.0789448;MT-ND3:S45P:T35A:4.19861:4.1339:0.0855016;MT-ND3:S45P:T35N:4.46139:4.1339:0.309927;MT-ND3:S45P:T35S:4.57446:4.1339:0.233842;MT-ND3:S45P:T35P:4.57535:4.1339:0.442305;MT-ND3:S45P:T35I:3.60392:4.1339:-0.515883;MT-ND3:S45P:M44T:4.71464:4.1339:0.4131;MT-ND3:S45P:M44K:4.25508:4.1339:0.331748;MT-ND3:S45P:M44I:4.34348:4.1339:0.322536;MT-ND3:S45P:M44V:4.66005:4.1339:0.489564;MT-ND3:S45P:M44L:4.29145:4.1339:0.360285;MT-ND3:S45P:A4P:2.705:4.1339:-1.526;MT-ND3:S45P:A4S:5.07628:4.1339:0.901348;MT-ND3:S45P:A4G:5.18293:4.1339:1.08914;MT-ND3:S45P:A4V:4.28057:4.1339:0.176529;MT-ND3:S45P:A4D:4.33837:4.1339:0.190562;MT-ND3:S45P:A4T:5.51494:4.1339:1.29799 | MT-ND3:S45C:L107P:5.50999:0.826151:4.56316;MT-ND3:S45C:L107M:0.6183:0.826151:-0.186263;MT-ND3:S45C:L107V:2.39813:0.826151:1.58272;MT-ND3:S45C:L107R:1.48454:0.826151:0.654602;MT-ND3:S45C:L107Q:1.73148:0.826151:0.964638;MT-ND3:S45C:D112Y:0.398607:0.826151:-0.433469;MT-ND3:S45C:D112E:0.546487:0.826151:-0.258161;MT-ND3:S45C:D112G:1.22005:0.826151:0.414236;MT-ND3:S45C:D112N:0.783482:0.826151:-0.0131052;MT-ND3:S45C:D112H:0.866113:0.826151:0.0340833;MT-ND3:S45C:D112A:0.3159:0.826151:-0.418179;MT-ND3:S45C:D112V:1.01008:0.826151:0.179616;MT-ND3:S45C:V49D:0.313673:0.826151:-0.607087;MT-ND3:S45C:V49G:1.84501:0.826151:0.888794;MT-ND3:S45C:V49A:1.14598:0.826151:0.193963;MT-ND3:S45C:V49L:0.552329:0.826151:-0.289594;MT-ND3:S45C:V49F:0.324433:0.826151:-0.639481;MT-ND3:S45C:V49I:0.920002:0.826151:-0.482548;MT-ND3:S45C:L79V:2.50222:0.826151:1.69291;MT-ND3:S45C:L79R:1.70268:0.826151:1.00907;MT-ND3:S45C:L79P:4.53785:0.826151:3.64483;MT-ND3:S45C:L79M:0.653034:0.826151:-0.174798;MT-ND3:S45C:L79Q:1.46177:0.826151:0.615227;MT-ND3:S45C:G29D:1.01752:0.826151:0.254493;MT-ND3:S45C:G29S:0.916085:0.826151:0.061955;MT-ND3:S45C:G29C:1.13128:0.826151:0.290877;MT-ND3:S45C:G29A:0.98033:0.826151:0.171581;MT-ND3:S45C:G29R:0.789326:0.826151:0.0789448;MT-ND3:S45C:G29V:1.34477:0.826151:0.518345;MT-ND3:S45C:T35S:1.25284:0.826151:0.233842;MT-ND3:S45C:T35P:1.29424:0.826151:0.442305;MT-ND3:S45C:T35N:1.15791:0.826151:0.309927;MT-ND3:S45C:T35A:0.893042:0.826151:0.0855016;MT-ND3:S45C:T35I:0.284032:0.826151:-0.515883;MT-ND3:S45C:M44T:1.22718:0.826151:0.4131;MT-ND3:S45C:M44L:1.00458:0.826151:0.360285;MT-ND3:S45C:M44K:1.03591:0.826151:0.331748;MT-ND3:S45C:M44I:0.999161:0.826151:0.322536;MT-ND3:S45C:M44V:1.22112:0.826151:0.489564;MT-ND3:S45C:A4G:1.86863:0.826151:1.08914;MT-ND3:S45C:A4D:0.997836:0.826151:0.190562;MT-ND3:S45C:A4S:1.7267:0.826151:0.901348;MT-ND3:S45C:A4T:2.06432:0.826151:1.29799;MT-ND3:S45C:A4V:1.26122:0.826151:0.176529;MT-ND3:S45C:A4P:-0.505855:0.826151:-1.526 | MT-ND3:S45Y:L107V:2.32591:0.6055:1.58272;MT-ND3:S45Y:L107P:5.40646:0.6055:4.56316;MT-ND3:S45Y:L107M:0.50254:0.6055:-0.186263;MT-ND3:S45Y:L107Q:1.68566:0.6055:0.964638;MT-ND3:S45Y:D112G:0.975755:0.6055:0.414236;MT-ND3:S45Y:D112A:0.227884:0.6055:-0.418179;MT-ND3:S45Y:D112H:0.669175:0.6055:0.0340833;MT-ND3:S45Y:D112E:0.459912:0.6055:-0.258161;MT-ND3:S45Y:D112N:0.62202:0.6055:-0.0131052;MT-ND3:S45Y:D112V:0.84797:0.6055:0.179616;MT-ND3:S45Y:V49L:0.396099:0.6055:-0.289594;MT-ND3:S45Y:V49F:0.056688:0.6055:-0.639481;MT-ND3:S45Y:V49D:0.062921:0.6055:-0.607087;MT-ND3:S45Y:V49I:0.872843:0.6055:-0.482548;MT-ND3:S45Y:V49G:1.62741:0.6055:0.888794;MT-ND3:S45Y:L79V:2.3271:0.6055:1.69291;MT-ND3:S45Y:L79M:0.571163:0.6055:-0.174798;MT-ND3:S45Y:L79R:1.5776:0.6055:1.00907;MT-ND3:S45Y:L79P:4.30922:0.6055:3.64483;MT-ND3:S45Y:D112Y:0.270734:0.6055:-0.433469;MT-ND3:S45Y:L79Q:1.29823:0.6055:0.615227;MT-ND3:S45Y:V49A:0.9252:0.6055:0.193963;MT-ND3:S45Y:L107R:1.29055:0.6055:0.654602;MT-ND3:S45Y:G29R:0.719265:0.6055:0.0789448;MT-ND3:S45Y:G29A:0.82546:0.6055:0.171581;MT-ND3:S45Y:G29S:0.697066:0.6055:0.061955;MT-ND3:S45Y:G29V:1.14448:0.6055:0.518345;MT-ND3:S45Y:G29D:0.87644:0.6055:0.254493;MT-ND3:S45Y:T35I:0.142279:0.6055:-0.515883;MT-ND3:S45Y:T35N:0.927255:0.6055:0.309927;MT-ND3:S45Y:T35S:1.02729:0.6055:0.233842;MT-ND3:S45Y:T35P:1.00572:0.6055:0.442305;MT-ND3:S45Y:M44T:1.12536:0.6055:0.4131;MT-ND3:S45Y:M44L:0.776645:0.6055:0.360285;MT-ND3:S45Y:M44V:0.89617:0.6055:0.489564;MT-ND3:S45Y:M44K:0.808765:0.6055:0.331748;MT-ND3:S45Y:A4V:1.06032:0.6055:0.176529;MT-ND3:S45Y:A4T:1.82082:0.6055:1.29799;MT-ND3:S45Y:A4P:-0.809287:0.6055:-1.526;MT-ND3:S45Y:A4S:1.52907:0.6055:0.901348;MT-ND3:S45Y:A4G:1.76796:0.6055:1.08914;MT-ND3:S45Y:T35A:0.755983:0.6055:0.0855016;MT-ND3:S45Y:M44I:0.480335:0.6055:0.322536;MT-ND3:S45Y:A4D:0.788075:0.6055:0.190562;MT-ND3:S45Y:G29C:0.904387:0.6055:0.290877 | MT-ND3:S45F:L107Q:1.49813:0.503661:0.964638;MT-ND3:S45F:L107V:2.17291:0.503661:1.58272;MT-ND3:S45F:L107M:0.271432:0.503661:-0.186263;MT-ND3:S45F:L107P:5.1301:0.503661:4.56316;MT-ND3:S45F:L107R:1.17674:0.503661:0.654602;MT-ND3:S45F:D112H:0.556441:0.503661:0.0340833;MT-ND3:S45F:D112N:0.492885:0.503661:-0.0131052;MT-ND3:S45F:D112A:0.0979919:0.503661:-0.418179;MT-ND3:S45F:D112Y:0.117732:0.503661:-0.433469;MT-ND3:S45F:D112G:0.813154:0.503661:0.414236;MT-ND3:S45F:D112E:0.348247:0.503661:-0.258161;MT-ND3:S45F:D112V:0.694058:0.503661:0.179616;MT-ND3:S45F:V49D:-0.0898759:0.503661:-0.607087;MT-ND3:S45F:V49F:-0.105163:0.503661:-0.639481;MT-ND3:S45F:V49A:0.791301:0.503661:0.193963;MT-ND3:S45F:V49I:0.785048:0.503661:-0.482548;MT-ND3:S45F:V49G:1.48081:0.503661:0.888794;MT-ND3:S45F:V49L:0.209412:0.503661:-0.289594;MT-ND3:S45F:L79V:2.08106:0.503661:1.69291;MT-ND3:S45F:L79M:0.39727:0.503661:-0.174798;MT-ND3:S45F:L79P:4.19811:0.503661:3.64483;MT-ND3:S45F:L79R:1.58043:0.503661:1.00907;MT-ND3:S45F:L79Q:1.15178:0.503661:0.615227;MT-ND3:S45F:G29D:0.777833:0.503661:0.254493;MT-ND3:S45F:G29V:0.893807:0.503661:0.518345;MT-ND3:S45F:G29S:0.558952:0.503661:0.061955;MT-ND3:S45F:G29A:0.710058:0.503661:0.171581;MT-ND3:S45F:G29R:0.637593:0.503661:0.0789448;MT-ND3:S45F:G29C:0.780297:0.503661:0.290877;MT-ND3:S45F:T35N:0.804215:0.503661:0.309927;MT-ND3:S45F:T35P:0.896665:0.503661:0.442305;MT-ND3:S45F:T35A:0.547631:0.503661:0.0855016;MT-ND3:S45F:T35I:-0.0204942:0.503661:-0.515883;MT-ND3:S45F:T35S:0.78972:0.503661:0.233842;MT-ND3:S45F:M44L:0.347368:0.503661:0.360285;MT-ND3:S45F:M44V:0.554149:0.503661:0.489564;MT-ND3:S45F:M44T:0.994677:0.503661:0.4131;MT-ND3:S45F:M44I:0.374943:0.503661:0.322536;MT-ND3:S45F:M44K:0.695619:0.503661:0.331748;MT-ND3:S45F:A4V:0.658189:0.503661:0.176529;MT-ND3:S45F:A4P:-0.934704:0.503661:-1.526;MT-ND3:S45F:A4G:1.57964:0.503661:1.08914;MT-ND3:S45F:A4T:1.65751:0.503661:1.29799;MT-ND3:S45F:A4D:0.708873:0.503661:0.190562;MT-ND3:S45F:A4S:1.27838:0.503661:0.901348 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| DDG intra interface | 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| MT-ND3:NDUFS2:5lc5:A:D:S45T:V49A:-0.142604:-0.269482:0.155824;MT-ND3:NDUFS2:5lc5:A:D:S45T:V49D:-0.319611:-0.269482:-0.028075;MT-ND3:NDUFS2:5lc5:A:D:S45T:V49F:-0.067598:-0.269482:0.166614;MT-ND3:NDUFS2:5lc5:A:D:S45T:V49G:-0.075341:-0.269482:0.140612;MT-ND3:NDUFS2:5lc5:A:D:S45T:V49I:-0.166487:-0.269482:0.109823;MT-ND3:NDUFS2:5lc5:A:D:S45T:V49L:-0.079242:-0.269482:0.185479;MT-ND3:MT-ND1:5lc5:A:H:S45T:L15F:0.94416:0.17377:0.77833;MT-ND3:MT-ND1:5lc5:A:H:S45T:L15M:0.29817:0.17377:0.1131;MT-ND3:MT-ND1:5lc5:A:H:S45T:L15S:1.38279:0.17377:1.28246;MT-ND3:MT-ND1:5lc5:A:H:S45T:L15V:1.32736:0.17377:1.06051;MT-ND3:MT-ND1:5lc5:A:H:S45T:L15W:-0.04049:0.17377:-0.4324;MT-ND3:MT-ND1:5lc5:A:H:S45T:M18I:0.83376:0.18219:0.66938;MT-ND3:MT-ND1:5lc5:A:H:S45T:M18K:2.68883:0.18219:2.49572;MT-ND3:MT-ND1:5lc5:A:H:S45T:M18L:0.70329:0.18219:0.5324;MT-ND3:MT-ND1:5lc5:A:H:S45T:M18T:2.69571:0.18219:2.4593;MT-ND3:MT-ND1:5lc5:A:H:S45T:M18V:1.64915:0.18219:1.36914;MT-ND3:MT-ND1:5lc5:A:H:S45T:T35A:0.42612:0.23364:0.14765;MT-ND3:MT-ND1:5lc5:A:H:S45T:T35I:0.10237:0.23364:-0.06767;MT-ND3:MT-ND1:5lc5:A:H:S45T:T35N:0.37601:0.23364:0.1598;MT-ND3:MT-ND1:5lc5:A:H:S45T:T35P:0.05681:0.23364:-0.18368;MT-ND3:MT-ND1:5lc5:A:H:S45T:T35S:0.07405:0.23364:-0.12436;MT-ND3:MT-ND1:5lc5:A:H:S45T:M44I:-1.24444:0.15893:-0.26598;MT-ND3:MT-ND1:5lc5:A:H:S45T:M44K:-1.21321:0.15893:-0.29543;MT-ND3:MT-ND1:5lc5:A:H:S45T:M44L:-0.76774:0.15893:-0.25651;MT-ND3:MT-ND1:5lc5:A:H:S45T:M44T:-0.64524:0.15893:0.06186;MT-ND3:MT-ND1:5lc5:A:H:S45T:M44V:-0.94635:0.15893:-0.15183;MT-ND3:MT-ND1:5ldw:A:H:S45T:L15F:0.53777:0.20131:0.16768;MT-ND3:MT-ND1:5ldw:A:H:S45T:L15M:-0.02397:0.20131:-0.22176;MT-ND3:MT-ND1:5ldw:A:H:S45T:L15S:0.9421:0.20131:0.71124;MT-ND3:MT-ND1:5ldw:A:H:S45T:L15V:0.56955:0.20131:0.32203;MT-ND3:MT-ND1:5ldw:A:H:S45T:L15W:-0.01047:0.20131:-0.12821;MT-ND3:MT-ND1:5ldw:A:H:S45T:M18I:0.466:0.18825:0.6076;MT-ND3:MT-ND1:5ldw:A:H:S45T:M18K:1.13309:0.18825:1.03939;MT-ND3:MT-ND1:5ldw:A:H:S45T:M18L:0.23677:0.18825:0.23679;MT-ND3:MT-ND1:5ldw:A:H:S45T:M18T:2.02409:0.18825:1.85929;MT-ND3:MT-ND1:5ldw:A:H:S45T:M18V:1.14142:0.18825:1.04567;MT-ND3:MT-ND1:5ldw:A:H:S45T:T35A:-0.76025:0.16123:-0.39186;MT-ND3:MT-ND1:5ldw:A:H:S45T:T35I:-0.27091:0.16123:-0.53034;MT-ND3:MT-ND1:5ldw:A:H:S45T:T35N:0.0535:0.16123:-0.30034;MT-ND3:MT-ND1:5ldw:A:H:S45T:T35P:-1.03145:0.16123:-0.80325;MT-ND3:MT-ND1:5ldw:A:H:S45T:T35S:-0.48439:0.16123:-0.19208;MT-ND3:MT-ND1:5ldw:A:H:S45T:M44I:-0.08871:0.1834:0.00493000000002;MT-ND3:MT-ND1:5ldw:A:H:S45T:M44K:0.03738:0.1834:-0.10369;MT-ND3:MT-ND1:5ldw:A:H:S45T:M44L:0.51183:0.1834:-0.10361;MT-ND3:MT-ND1:5ldw:A:H:S45T:M44T:-0.08413:0.1834:0.01395;MT-ND3:MT-ND1:5ldw:A:H:S45T:M44V:0.01719:0.1834:0.0288;MT-ND3:MT-ND1:5ldx:A:H:S45T:L15F:1.15263:0.5621:0.54581;MT-ND3:MT-ND1:5ldx:A:H:S45T:L15M:0.32143:0.5621:-0.21274;MT-ND3:MT-ND1:5ldx:A:H:S45T:L15S:1.06309:0.5621:0.64412;MT-ND3:MT-ND1:5ldx:A:H:S45T:L15V:1.04289:0.5621:0.48811;MT-ND3:MT-ND1:5ldx:A:H:S45T:L15W:0.18279:0.5621:-0.23467;MT-ND3:MT-ND1:5ldx:A:H:S45T:M18I:1.35605:0.53533:0.65117;MT-ND3:MT-ND1:5ldx:A:H:S45T:M18K:1.86029:0.53533:1.20633;MT-ND3:MT-ND1:5ldx:A:H:S45T:M18L:0.56567:0.53533:0.49592;MT-ND3:MT-ND1:5ldx:A:H:S45T:M18T:2.37079:0.53533:1.70221;MT-ND3:MT-ND1:5ldx:A:H:S45T:M18V:1.60746:0.53533:1.12518;MT-ND3:MT-ND1:5ldx:A:H:S45T:T35A:0.47212:0.53239:-0.28604;MT-ND3:MT-ND1:5ldx:A:H:S45T:T35I:0.22983:0.53239:-0.5748;MT-ND3:MT-ND1:5ldx:A:H:S45T:T35N:0.45945:0.53239:-0.12195;MT-ND3:MT-ND1:5ldx:A:H:S45T:T35P:-0.17436:0.53239:-0.88659;MT-ND3:MT-ND1:5ldx:A:H:S45T:T35S:0.48873:0.53239:-0.18413;MT-ND3:MT-ND1:5ldx:A:H:S45T:M44I:0.44152:0.55968:-0.03478;MT-ND3:MT-ND1:5ldx:A:H:S45T:M44K:0.60991:0.55968:-0.07642;MT-ND3:MT-ND1:5ldx:A:H:S45T:M44L:0.50732:0.55968:-0.07877;MT-ND3:MT-ND1:5ldx:A:H:S45T:M44T:0.68112:0.55968:0.03867;MT-ND3:MT-ND1:5ldx:A:H:S45T:M44V:0.56757:0.55968:0.04435 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MT-ND3:NDUFS2:5lc5:A:D:S45F:V49A:-1.2844962:-1.1369547:0.155824;MT-ND3:NDUFS2:5lc5:A:D:S45F:V49D:-1.5460474:-1.1369547:-0.028075;MT-ND3:NDUFS2:5lc5:A:D:S45F:V49F:-1.2483167:-1.1369547:0.166614;MT-ND3:NDUFS2:5lc5:A:D:S45F:V49G:-1.0306:-1.1369547:0.140612;MT-ND3:NDUFS2:5lc5:A:D:S45F:V49I:-1.4003141:-1.1369547:0.109823;MT-ND3:NDUFS2:5lc5:A:D:S45F:V49L:-1.2673499:-1.1369547:0.185479;MT-ND3:MT-ND1:5lc5:A:H:S45F:L15F:0.36638:-0.27181:0.77833;MT-ND3:MT-ND1:5lc5:A:H:S45F:L15M:-0.18265:-0.27181:0.1131;MT-ND3:MT-ND1:5lc5:A:H:S45F:L15S:1.11228:-0.27181:1.28246;MT-ND3:MT-ND1:5lc5:A:H:S45F:L15V:0.77572:-0.27181:1.06051;MT-ND3:MT-ND1:5lc5:A:H:S45F:L15W:-0.50368:-0.27181:-0.4324;MT-ND3:MT-ND1:5lc5:A:H:S45F:M18I:0.49106:-0.27178:0.66938;MT-ND3:MT-ND1:5lc5:A:H:S45F:M18K:2.2519:-0.27178:2.49572;MT-ND3:MT-ND1:5lc5:A:H:S45F:M18L:0.31462:-0.27178:0.5324;MT-ND3:MT-ND1:5lc5:A:H:S45F:M18T:2.24102:-0.27178:2.4593;MT-ND3:MT-ND1:5lc5:A:H:S45F:M18V:1.10345:-0.27178:1.36914;MT-ND3:MT-ND1:5lc5:A:H:S45F:T35A:-0.12098:-0.27365:0.14765;MT-ND3:MT-ND1:5lc5:A:H:S45F:T35I:-0.25428:-0.27365:-0.06767;MT-ND3:MT-ND1:5lc5:A:H:S45F:T35N:-0.04763:-0.27365:0.1598;MT-ND3:MT-ND1:5lc5:A:H:S45F:T35P:-0.42:-0.27365:-0.18368;MT-ND3:MT-ND1:5lc5:A:H:S45F:T35S:-0.37544:-0.27365:-0.12436;MT-ND3:MT-ND1:5lc5:A:H:S45F:M44I:-0.4842:-0.26155:-0.26598;MT-ND3:MT-ND1:5lc5:A:H:S45F:M44K:-0.39465:-0.26155:-0.29543;MT-ND3:MT-ND1:5lc5:A:H:S45F:M44L:-0.34863:-0.26155:-0.25651;MT-ND3:MT-ND1:5lc5:A:H:S45F:M44T:-0.11156:-0.26155:0.06186;MT-ND3:MT-ND1:5lc5:A:H:S45F:M44V:-0.30967:-0.26155:-0.15183;MT-ND3:MT-ND1:5ldw:A:H:S45F:L15F:0.49933:0.01284:0.16768;MT-ND3:MT-ND1:5ldw:A:H:S45F:L15M:-0.32746:0.01284:-0.22176;MT-ND3:MT-ND1:5ldw:A:H:S45F:L15S:0.66074:0.01284:0.71124;MT-ND3:MT-ND1:5ldw:A:H:S45F:L15V:0.36578:0.01284:0.32203;MT-ND3:MT-ND1:5ldw:A:H:S45F:L15W:-0.09059:0.01284:-0.12821;MT-ND3:MT-ND1:5ldw:A:H:S45F:M18I:0.85928:0.01343:0.6076;MT-ND3:MT-ND1:5ldw:A:H:S45F:M18K:0.73576:0.01343:1.03939;MT-ND3:MT-ND1:5ldw:A:H:S45F:M18L:0.43312:0.01343:0.23679;MT-ND3:MT-ND1:5ldw:A:H:S45F:M18T:1.96731:0.01343:1.85929;MT-ND3:MT-ND1:5ldw:A:H:S45F:M18V:1.24718:0.01343:1.04567;MT-ND3:MT-ND1:5ldw:A:H:S45F:T35A:-0.39977:0.10391:-0.39186;MT-ND3:MT-ND1:5ldw:A:H:S45F:T35I:-0.50429:0.10391:-0.53034;MT-ND3:MT-ND1:5ldw:A:H:S45F:T35N:-0.30707:0.10391:-0.30034;MT-ND3:MT-ND1:5ldw:A:H:S45F:T35P:-0.93427:0.10391:-0.80325;MT-ND3:MT-ND1:5ldw:A:H:S45F:T35S:-0.36963:0.10391:-0.19208;MT-ND3:MT-ND1:5ldw:A:H:S45F:M44I:-0.1464:0.07069:0.00493000000002;MT-ND3:MT-ND1:5ldw:A:H:S45F:M44K:0.08844:0.07069:-0.10369;MT-ND3:MT-ND1:5ldw:A:H:S45F:M44L:0.11065:0.07069:-0.10361;MT-ND3:MT-ND1:5ldw:A:H:S45F:M44T:0.29087:0.07069:0.01395;MT-ND3:MT-ND1:5ldw:A:H:S45F:M44V:-0.15865:0.07069:0.0288;MT-ND3:MT-ND1:5ldx:A:H:S45F:L15F:1.05745:0.50513:0.54581;MT-ND3:MT-ND1:5ldx:A:H:S45F:L15M:0.22456:0.50513:-0.21274;MT-ND3:MT-ND1:5ldx:A:H:S45F:L15S:1.1544:0.50513:0.64412;MT-ND3:MT-ND1:5ldx:A:H:S45F:L15V:0.99582:0.50513:0.48811;MT-ND3:MT-ND1:5ldx:A:H:S45F:L15W:0.27385:0.50513:-0.23467;MT-ND3:MT-ND1:5ldx:A:H:S45F:M18I:1.16602:0.50899:0.65117;MT-ND3:MT-ND1:5ldx:A:H:S45F:M18K:1.70963:0.50899:1.20633;MT-ND3:MT-ND1:5ldx:A:H:S45F:M18L:0.91289:0.50899:0.49592;MT-ND3:MT-ND1:5ldx:A:H:S45F:M18T:2.30901:0.50899:1.70221;MT-ND3:MT-ND1:5ldx:A:H:S45F:M18V:1.52245:0.50899:1.12518;MT-ND3:MT-ND1:5ldx:A:H:S45F:T35A:0.20521:0.50768:-0.28604;MT-ND3:MT-ND1:5ldx:A:H:S45F:T35I:-0.0618:0.50768:-0.5748;MT-ND3:MT-ND1:5ldx:A:H:S45F:T35N:0.27494:0.50768:-0.12195;MT-ND3:MT-ND1:5ldx:A:H:S45F:T35P:-0.35732:0.50768:-0.88659;MT-ND3:MT-ND1:5ldx:A:H:S45F:T35S:0.26535:0.50768:-0.18413;MT-ND3:MT-ND1:5ldx:A:H:S45F:M44I:0.85083:0.5088:-0.03478;MT-ND3:MT-ND1:5ldx:A:H:S45F:M44K:0.51116:0.5088:-0.07642;MT-ND3:MT-ND1:5ldx:A:H:S45F:M44L:0.87592:0.5088:-0.07877;MT-ND3:MT-ND1:5ldx:A:H:S45F:M44T:0.58676:0.5088:0.03867;MT-ND3:MT-ND1:5ldx:A:H:S45F:M44V:0.90803:0.5088:0.04435 |
| DDG inter | 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