news model
license
| ~ | 3682 (A/G) | 3682 (A/T) | 3682 (A/C) | 3683 (A/T) | 3683 (A/G) | 3683 (A/C) | 3684 (C/G) | 3684 (C/A) |
|---|---|---|---|---|---|---|---|---|
| ~ | 3682 (Aac/Gac) | 3682 (Aac/Tac) | 3682 (Aac/Cac) | 3683 (aAc/aTc) | 3683 (aAc/aGc) | 3683 (aAc/aCc) | 3684 (aaC/aaG) | 3684 (aaC/aaA) |
| Chr | chrM | chrM | chrM | chrM | chrM | chrM | chrM | chrM |
| Start | 3682 | 3682 | 3682 | 3683 | 3683 | 3683 | 3684 | 3684 |
| End | 3682 | 3682 | 3682 | 3683 | 3683 | 3683 | 3684 | 3684 |
| Ref | A | A | A | A | A | A | C | C |
| Alt | G | T | C | T | G | C | G | A |
| MitImpact id | MI.11533 | MI.11534 | MI.11535 | MI.11536 | MI.11537 | MI.11538 | MI.11539 | MI.11540 |
| Gene symbol | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 | MT-ND1 |
| Respiratory Chain complex | I | I | I | I | I | I | I | I |
| Ensembl gene id | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 | ENSG00000198888 |
| Ensembl protein id | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 | ENSP00000354687 |
| Ensembl transcript id | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 | ENST00000361390 |
| Uniprot name | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN | NU1M_HUMAN |
| Uniprot id | P03886 | P03886 | P03886 | P03886 | P03886 | P03886 | P03886 | P03886 |
| Ncbi gene id | 4535 | 4535 | 4535 | 4535 | 4535 | 4535 | 4535 | 4535 |
| Ncbi protein id | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 | YP_003024026.1 |
| Gene position | 376 | 376 | 376 | 377 | 377 | 377 | 378 | 378 |
| AA position | 126 | 126 | 126 | 126 | 126 | 126 | 126 | 126 |
| AA ref | N | N | N | N | N | N | N | N |
| AA alt | D | Y | H | I | S | T | K | K |
| Codon substitution | Aac/Gac | Aac/Tac | Aac/Cac | aAc/aTc | aAc/aGc | aAc/aCc | aaC/aaG | aaC/aaA |
| PhyloP 100V | -1.62 | -1.62 | -1.62 | 8.49 | 8.49 | 8.49 | 6.65 | 6.65 |
| PhastCons 100V | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
| PolyPhen2 | possibly_damaging | probably_damaging | probably_damaging | probably_damaging | possibly_damaging | possibly_damaging | benign | benign |
| PolyPhen2 score | 0.72 | 0.96 | 0.95 | 0.95 | 0.53 | 0.72 | 0.03 | 0.03 |
| SIFT | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| SIFT score | 0.2 | 1 | 0.52 | 0.4 | 0.64 | 0.38 | 0.37 | 0.37 |
| FatHmm | neutral | deleterious | neutral | neutral | neutral | neutral | neutral | neutral |
| FatHmm score | -1 | -3.02 | -2.13 | -2.63 | -0.97 | -1.35 | 2.2 | 2.2 |
| FatHmmW | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| FatHmmW score | 2.74 | 2.68 | 2.7 | 2.69 | 2.74 | 2.72 | 3.23 | 3.23 |
| PROVEAN | neutral | neutral | neutral | deleterious | neutral | neutral | neutral | neutral |
| PROVEAN score | -1.03 | -1.98 | -1.04 | -2.91 | -0.15 | -1.05 | 4.14 | 4.14 |
| MutationAssessor | medium impact | medium impact | medium impact | low impact | low impact | medium impact | neutral impact | neutral impact |
| MutationAssessor score | 2.94 | 2.04 | 2.59 | 1.47 | 1.24 | 2.24 | -1.8 | -1.8 |
| EFIN SP | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| EFIN SP score | 0.66 | 0.68 | 0.64 | 0.67 | 0.78 | 0.63 | 0.7 | 0.7 |
| EFIN HD | damaging | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| EFIN HD score | 0.25 | 0.3 | 0.28 | 0.28 | 0.28 | 0.3 | 0.81 | 0.81 |
| CADD | deleterious | deleterious | deleterious | deleterious | deleterious | deleterious | neutral | neutral |
| CADD score | 3.84 | 3.75 | 3.08 | 3.75 | 2.94 | 3.26 | 1.27 | 1.69 |
| CADD phred | 23.4 | 23.3 | 22.5 | 23.3 | 22 | 22.8 | 12.09 | 14.36 |
| VEST pvalue | 0.64 | 0.08 | 0.4 | 0.12 | 0.55 | 0.38 | 0.49 | 0.49 |
| VEST FDR | 0.7 | 0.35 | 0.5 | 0.4 | 0.6 | 0.5 | 0.55 | 0.55 |
| PANTHER | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| PANTHER score | 0.22 | 0.44 | 0.34 | 0.37 | 0.14 | 0.18 | 0.23 | 0.23 |
| PhD-SNP | disease | disease | neutral | disease | neutral | neutral | neutral | neutral |
| PhD-SNP score | 0.61 | 0.7 | 0.47 | 0.78 | 0.48 | 0.49 | 0.05 | 0.05 |
| SNAP | disease | disease | disease | disease | neutral | disease | neutral | neutral |
| SNAP score | 0.62 | 0.62 | 0.63 | 0.58 | 0.49 | 0.57 | 0.26 | 0.26 |
| Meta-SNP | disease | disease | disease | disease | neutral | disease | neutral | neutral |
| Meta-SNP score | 0.7 | 0.7 | 0.53 | 0.72 | 0.43 | 0.56 | 0.18 | 0.18 |
| Meta-SNP RI | 4 | 4 | 1 | 4 | 1 | 1 | 6 | 6 |
| CAROL | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| CAROL score | 0.85 | 0.96 | 0.94 | 0.95 | 0.45 | 0.74 | 0.61 | 0.61 |
| Condel | neutral | deleterious | neutral | neutral | deleterious | neutral | deleterious | deleterious |
| Condel score | 0.24 | 0.52 | 0.29 | 0.23 | 0.56 | 0.33 | 0.67 | 0.67 |
| COVEC WMV | . | deleterious | deleterious | neutral | neutral | . | neutral | neutral |
| COVEC WMV score | 0 | 1 | 1 | -2 | -3 | 0 | -6 | -6 |
| MtoolBox | deleterious | deleterious | deleterious | deleterious | deleterious | deleterious | neutral | neutral |
| MtoolBox DS | 0.57 | 0.75 | 0.68 | 0.75 | 0.44 | 0.54 | 0.12 | 0.12 |
| PolyPhen2 transf | low impact | low impact | low impact | low impact | medium impact | low impact | medium impact | medium impact |
| PolyPhen2 transf score | -1.14 | -2.05 | -1.95 | -1.95 | -0.8 | -1.14 | 0.67 | 0.67 |
| SIFT_transf | medium impact | high impact | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact |
| SIFT transf score | -0.06 | 1.96 | 0.29 | 0.18 | 0.42 | 0.16 | 0.15 | 0.15 |
| MutationAssessor transf | medium impact | medium impact | medium impact | medium impact | medium impact | medium impact | low impact | low impact |
| MutationAssessor transf score | 1.38 | 0.59 | 1.07 | 0.1 | -0.11 | 0.77 | -2.76 | -2.76 |
| CHASM pvalue | 0.29 | 0.17 | 0.14 | 0.14 | 0.15 | 0.2 | 0.41 | 0.41 |
| CHASM FDR | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 |
| APOGEE | VUS | VUS | VUS | VUS | Likely-benign | VUS | Benign | Benign |
| APOGEE score | 0.4264436259871658 | 0.503503464172336 | 0.4568331191069038 | 0.5241455895977107 | 0.2440664541644133 | 0.478997614296898 | 0.0470912772278902 | 0.0470912772278902 |
| SNPDryad score | 0.68 | 0.93 | 0.38 | 0.92 | 0.31 | 0.43 | 0.11 | 0.11 |
| MutationTaster | polymorphism | polymorphism | polymorphism | polymorphism | polymorphism | polymorphism | polymorphism | polymorphism |
| MutationTaster score | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| DEOGEN2 score | 0.12 | 0.05 | 0.05 | 0.11 | 0.01 | 0.03 | 0.01 | 0.01 |
| Mitoclass.1 | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| dbSNP 155 id | . | . | . | . | . | . | . | . |
| ClinVar October2021 Variation id | . | . | . | . | . | . | . | . |
| ClinVar October2021 CLNSIG | . | . | . | . | . | . | . | . |
| ClinVar October2021 CLNDN | . | . | . | . | . | . | . | . |
| ClinVar October2021 CLNDISDB | . | . | . | . | . | . | . | . |
| COSMIC 90 | . | . | . | . | . | . | . | . |
| MITOMAP Allele | . | . | . | . | . | . | . | . |
| MITOMAP Disease Het/Hom | . | . | . | . | . | . | . | . |
| MITOMAP Disease Clinical info | . | . | . | . | . | . | . | . |
| MITOMAP Disease Status | . | . | . | . | . | . | . | . |
| MITOMAP Disease GenBank Freq | . | . | . | . | . | . | . | . |
| MITOMAP Disease GenBank Seqs | . | . | . | . | . | . | . | . |
| MITOMAP Disease GenBank Curated refs | . | . | . | . | . | . | . | . |
| MITOMAP General GenBank Freq | . | . | . | . | . | . | . | 0.002% |
| MITOMAP General GenBank Seqs | . | . | . | . | . | . | . | 1 |
| MITOMAP General Curated refs | . | . | . | . | . | . | . | 1 |
| gnomAD 3.1 filter | . | . | . | . | PASS | . | . | PASS |
| gnomAD 3.1 AC Homo | . | . | . | . | 0 | . | . | 3 |
| gnomAD 3.1 AC Het | . | . | . | . | 2 | . | . | 0 |
| gnomAD 3.1 AF Hom | . | . | . | . | 0 | . | . | 5.315944e-05 |
| gnomAD 3.1 AF Het | . | . | . | . | 3.543963e-05 | . | . | 0 |
| gnomAD 3.1 AN | . | . | . | . | 56434 | . | . | 56434 |
| HelixMTdb AC Hom | . | . | . | . | . | . | . | . |
| HelixMTdb AF Hom | . | . | . | . | . | . | . | . |
| HelixMTdb AC Het | . | . | . | . | . | . | . | . |
| HelixMTdb AF Het | . | . | . | . | . | . | . | . |
| HelixMTdb mean ARF | . | . | . | . | . | . | . | . | HelixMTdb max ARF | . | . | . | . | . | . | . | . |
| EVmutation | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 | MT-ND1_126N|128A:0.161216;129L:0.079319 |
| Site A InterP | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 |
| Site B InterP | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 | ND2_241;ND2_308;ND2_281;ND3_22;ND4_333;ND4_421;ND5_301;ND5_309;ND5_373;ND5_549;ND5_37;ND6_126;ND2_166;ND2_281;ND2_286;ND3_18;ND3_45;ND3_112;ND3_49;ND3_46;ND3_21;ND4_363;ND4_62;ND4_345;ND4L_87;ND4L_91;ND5_428;ND5_420;ND5_480;ND6_85;ND6_50 |
| Covariation Score InterP | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 | mfDCA_37.23;mfDCA_31.67;cMI_47.7782;mfDCA_27.67;mfDCA_27.98;mfDCA_24.54;mfDCA_52.42;mfDCA_50.46;mfDCA_46.59;mfDCA_31.49;mfDCA_29.97;mfDCA_25.5;cMI_69.34426;cMI_47.7782;cMI_46.96695;cMI_52.28324;cMI_41.72575;cMI_41.22761;cMI_38.78658;cMI_38.5613;cMI_38.1969;cMI_28.74507;cMI_27.11921;cMI_24.45732;cMI_49.41002;cMI_45.50344;cMI_33.70751;cMI_31.03174;cMI_29.24682;cMI_62.30736;cMI_52.77064 |
| Site A IntraP | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 | ND1_126 |
| Site B IntraP | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 | ND1_161;ND1_67;ND1_81;ND1_71;ND1_276;ND1_84;ND1_249;ND1_213;ND1_240 |
| Covariation Score IntraP | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 | cMI_17.751915;cMI_15.849877;cMI_15.512266;cMI_15.365741;cMI_15.33259;cMI_14.790646;cMI_14.414145;cMI_14.05986;cMI_13.257043 |
| CPD AA ref | . | . | . | . | . | . | . | . |
| CPD AA alt | . | . | . | . | . | . | . | . |
| CPD Aln pos | . | . | . | . | . | . | . | . |
| CPD Frequency | . | . | . | . | . | . | . | . |
| CPD Species name | . | . | . | . | . | . | . | . |
| CPD RefSeq Protein ID | . | . | . | . | . | . | . | . |
| CPD Ncbi Taxon id | . | . | . | . | . | . | . | . |
| DDG intra | MT-ND1:N126D:I213N:-0.80312:-1.35328:0.570276;MT-ND1:N126D:I213S:-0.715128:-1.35328:0.54308;MT-ND1:N126D:I213F:-1.56103:-1.35328:-0.142791;MT-ND1:N126D:I213V:-1.34912:-1.35328:-0.133635;MT-ND1:N126D:I213T:-1.36419:-1.35328:-0.123203;MT-ND1:N126D:I213L:-2.06085:-1.35328:-0.717595;MT-ND1:N126D:I213M:-1.88268:-1.35328:-0.483465;MT-ND1:N126D:A249P:-2.33383:-1.35328:-0.969457;MT-ND1:N126D:A249T:-0.73683:-1.35328:0.585672;MT-ND1:N126D:A249V:-0.941099:-1.35328:0.387706;MT-ND1:N126D:A249S:-0.947884:-1.35328:0.416877;MT-ND1:N126D:A249E:-1.38265:-1.35328:-0.081467;MT-ND1:N126D:A249G:-1.0733:-1.35328:0.24999;MT-ND1:N126D:A276S:-1.51652:-1.35328:-0.200186;MT-ND1:N126D:A276G:-0.980347:-1.35328:0.386782;MT-ND1:N126D:A276E:-1.26429:-1.35328:0.0557187;MT-ND1:N126D:A276P:-0.238444:-1.35328:1.16054;MT-ND1:N126D:A276V:-0.724091:-1.35328:0.62968;MT-ND1:N126D:A276T:-0.688079:-1.35328:0.683193 | MT-ND1:N126Y:I213L:-2.03197:-1.04055:-0.717595;MT-ND1:N126Y:I213S:-0.647457:-1.04055:0.54308;MT-ND1:N126Y:I213F:-1.38274:-1.04055:-0.142791;MT-ND1:N126Y:I213T:-1.2891:-1.04055:-0.123203;MT-ND1:N126Y:I213V:-1.38109:-1.04055:-0.133635;MT-ND1:N126Y:I213N:-0.777702:-1.04055:0.570276;MT-ND1:N126Y:I213M:-1.61687:-1.04055:-0.483465;MT-ND1:N126Y:A249S:-0.723282:-1.04055:0.416877;MT-ND1:N126Y:A249P:-2.1532:-1.04055:-0.969457;MT-ND1:N126Y:A249V:-0.840571:-1.04055:0.387706;MT-ND1:N126Y:A249G:-0.773844:-1.04055:0.24999;MT-ND1:N126Y:A249E:-1.3226:-1.04055:-0.081467;MT-ND1:N126Y:A249T:-0.634344:-1.04055:0.585672;MT-ND1:N126Y:A276E:-0.963784:-1.04055:0.0557187;MT-ND1:N126Y:A276G:-0.878653:-1.04055:0.386782;MT-ND1:N126Y:A276V:-0.517871:-1.04055:0.62968;MT-ND1:N126Y:A276S:-1.38693:-1.04055:-0.200186;MT-ND1:N126Y:A276P:-0.0305314:-1.04055:1.16054;MT-ND1:N126Y:A276T:-0.494543:-1.04055:0.683193 | MT-ND1:N126H:I213M:-1.09881:-0.611863:-0.483465;MT-ND1:N126H:I213F:-0.87268:-0.611863:-0.142791;MT-ND1:N126H:I213V:-0.637399:-0.611863:-0.133635;MT-ND1:N126H:I213N:-0.0260564:-0.611863:0.570276;MT-ND1:N126H:I213S:0.0570077:-0.611863:0.54308;MT-ND1:N126H:I213L:-1.34997:-0.611863:-0.717595;MT-ND1:N126H:I213T:-0.65633:-0.611863:-0.123203;MT-ND1:N126H:A249S:-0.198075:-0.611863:0.416877;MT-ND1:N126H:A249T:0.0464597:-0.611863:0.585672;MT-ND1:N126H:A249V:-0.214322:-0.611863:0.387706;MT-ND1:N126H:A249P:-1.57716:-0.611863:-0.969457;MT-ND1:N126H:A249E:-0.717267:-0.611863:-0.081467;MT-ND1:N126H:A249G:-0.327082:-0.611863:0.24999;MT-ND1:N126H:A276S:-0.780954:-0.611863:-0.200186;MT-ND1:N126H:A276G:-0.211246:-0.611863:0.386782;MT-ND1:N126H:A276E:-0.529948:-0.611863:0.0557187;MT-ND1:N126H:A276P:0.617763:-0.611863:1.16054;MT-ND1:N126H:A276V:0.0245213:-0.611863:0.62968;MT-ND1:N126H:A276T:0.0825789:-0.611863:0.683193 | MT-ND1:N126I:I213N:-0.568668:-1.02185:0.570276;MT-ND1:N126I:I213S:-0.429043:-1.02185:0.54308;MT-ND1:N126I:I213L:-1.8485:-1.02185:-0.717595;MT-ND1:N126I:I213T:-1.10267:-1.02185:-0.123203;MT-ND1:N126I:I213V:-1.18064:-1.02185:-0.133635;MT-ND1:N126I:I213F:-1.19071:-1.02185:-0.142791;MT-ND1:N126I:A249G:-0.776523:-1.02185:0.24999;MT-ND1:N126I:A249V:-0.670835:-1.02185:0.387706;MT-ND1:N126I:A249E:-0.916627:-1.02185:-0.081467;MT-ND1:N126I:A249T:-0.41351:-1.02185:0.585672;MT-ND1:N126I:A249P:-1.9954:-1.02185:-0.969457;MT-ND1:N126I:A276V:-0.395256:-1.02185:0.62968;MT-ND1:N126I:A276E:-0.975685:-1.02185:0.0557187;MT-ND1:N126I:A276P:0.183424:-1.02185:1.16054;MT-ND1:N126I:A276G:-0.613625:-1.02185:0.386782;MT-ND1:N126I:A276S:-1.21579:-1.02185:-0.200186;MT-ND1:N126I:A276T:-0.310528:-1.02185:0.683193;MT-ND1:N126I:A249S:-0.624187:-1.02185:0.416877;MT-ND1:N126I:I213M:-1.49176:-1.02185:-0.483465 | MT-ND1:N126S:I213S:0.773977:0.210032:0.54308;MT-ND1:N126S:I213F:0.00909783:0.210032:-0.142791;MT-ND1:N126S:I213N:0.585099:0.210032:0.570276;MT-ND1:N126S:I213L:-0.515264:0.210032:-0.717595;MT-ND1:N126S:I213T:0.103584:0.210032:-0.123203;MT-ND1:N126S:I213M:-0.25648:0.210032:-0.483465;MT-ND1:N126S:I213V:0.177965:0.210032:-0.133635;MT-ND1:N126S:A249E:0.242351:0.210032:-0.081467;MT-ND1:N126S:A249G:0.496239:0.210032:0.24999;MT-ND1:N126S:A249S:0.616427:0.210032:0.416877;MT-ND1:N126S:A249T:0.814568:0.210032:0.585672;MT-ND1:N126S:A249V:0.608905:0.210032:0.387706;MT-ND1:N126S:A249P:-0.743712:0.210032:-0.969457;MT-ND1:N126S:A276T:0.871773:0.210032:0.683193;MT-ND1:N126S:A276G:0.586774:0.210032:0.386782;MT-ND1:N126S:A276P:1.49278:0.210032:1.16054;MT-ND1:N126S:A276V:0.852967:0.210032:0.62968;MT-ND1:N126S:A276E:0.283738:0.210032:0.0557187;MT-ND1:N126S:A276S:0.0186631:0.210032:-0.200186 | MT-ND1:N126T:I213F:-0.161443:0.0249942:-0.142791;MT-ND1:N126T:I213S:0.563877:0.0249942:0.54308;MT-ND1:N126T:I213L:-0.714951:0.0249942:-0.717595;MT-ND1:N126T:I213N:0.518234:0.0249942:0.570276;MT-ND1:N126T:I213T:-0.0862825:0.0249942:-0.123203;MT-ND1:N126T:I213M:-0.484902:0.0249942:-0.483465;MT-ND1:N126T:I213V:-0.0450998:0.0249942:-0.133635;MT-ND1:N126T:A249P:-0.962049:0.0249942:-0.969457;MT-ND1:N126T:A249E:0.0931174:0.0249942:-0.081467;MT-ND1:N126T:A249G:0.296433:0.0249942:0.24999;MT-ND1:N126T:A249S:0.435213:0.0249942:0.416877;MT-ND1:N126T:A249T:0.593129:0.0249942:0.585672;MT-ND1:N126T:A249V:0.425138:0.0249942:0.387706;MT-ND1:N126T:A276S:-0.206018:0.0249942:-0.200186;MT-ND1:N126T:A276P:1.1948:0.0249942:1.16054;MT-ND1:N126T:A276V:0.678573:0.0249942:0.62968;MT-ND1:N126T:A276T:0.727631:0.0249942:0.683193;MT-ND1:N126T:A276G:0.421614:0.0249942:0.386782;MT-ND1:N126T:A276E:0.103294:0.0249942:0.0557187 | MT-ND1:N126K:I213M:-1.22772:-0.694078:-0.483465;MT-ND1:N126K:I213V:-0.7669:-0.694078:-0.133635;MT-ND1:N126K:I213T:-0.770749:-0.694078:-0.123203;MT-ND1:N126K:I213L:-1.44404:-0.694078:-0.717595;MT-ND1:N126K:I213F:-0.974428:-0.694078:-0.142791;MT-ND1:N126K:I213N:-0.206493:-0.694078:0.570276;MT-ND1:N126K:I213S:-0.124558:-0.694078:0.54308;MT-ND1:N126K:A249S:-0.27373:-0.694078:0.416877;MT-ND1:N126K:A249V:-0.2602:-0.694078:0.387706;MT-ND1:N126K:A249E:-0.699514:-0.694078:-0.081467;MT-ND1:N126K:A249P:-1.68144:-0.694078:-0.969457;MT-ND1:N126K:A249G:-0.448006:-0.694078:0.24999;MT-ND1:N126K:A249T:-0.158863:-0.694078:0.585672;MT-ND1:N126K:A276V:-0.0985182:-0.694078:0.62968;MT-ND1:N126K:A276T:-0.0597012:-0.694078:0.683193;MT-ND1:N126K:A276G:-0.310009:-0.694078:0.386782;MT-ND1:N126K:A276P:0.614259:-0.694078:1.16054;MT-ND1:N126K:A276E:-0.673986:-0.694078:0.0557187;MT-ND1:N126K:A276S:-0.930457:-0.694078:-0.200186 | MT-ND1:N126K:I213M:-1.22772:-0.694078:-0.483465;MT-ND1:N126K:I213V:-0.7669:-0.694078:-0.133635;MT-ND1:N126K:I213T:-0.770749:-0.694078:-0.123203;MT-ND1:N126K:I213L:-1.44404:-0.694078:-0.717595;MT-ND1:N126K:I213F:-0.974428:-0.694078:-0.142791;MT-ND1:N126K:I213N:-0.206493:-0.694078:0.570276;MT-ND1:N126K:I213S:-0.124558:-0.694078:0.54308;MT-ND1:N126K:A249S:-0.27373:-0.694078:0.416877;MT-ND1:N126K:A249V:-0.2602:-0.694078:0.387706;MT-ND1:N126K:A249E:-0.699514:-0.694078:-0.081467;MT-ND1:N126K:A249P:-1.68144:-0.694078:-0.969457;MT-ND1:N126K:A249G:-0.448006:-0.694078:0.24999;MT-ND1:N126K:A249T:-0.158863:-0.694078:0.585672;MT-ND1:N126K:A276V:-0.0985182:-0.694078:0.62968;MT-ND1:N126K:A276T:-0.0597012:-0.694078:0.683193;MT-ND1:N126K:A276G:-0.310009:-0.694078:0.386782;MT-ND1:N126K:A276P:0.614259:-0.694078:1.16054;MT-ND1:N126K:A276E:-0.673986:-0.694078:0.0557187;MT-ND1:N126K:A276S:-0.930457:-0.694078:-0.200186 |
| DDG intra interface | MT-ND1:MT-ND3:5lc5:H:A:N126D:I213F:1.7402:1.72653:0.26227;MT-ND1:MT-ND3:5lc5:H:A:N126D:I213L:1.69618:1.72653:0.02712;MT-ND1:MT-ND3:5lc5:H:A:N126D:I213M:1.80926:1.72653:0.09873;MT-ND1:MT-ND3:5lc5:H:A:N126D:I213N:0.98656:1.72653:-0.64295;MT-ND1:MT-ND3:5lc5:H:A:N126D:I213S:1.68481:1.72653:-0.01554;MT-ND1:MT-ND3:5lc5:H:A:N126D:I213T:1.86616:1.72653:0.0437;MT-ND1:MT-ND3:5lc5:H:A:N126D:I213V:1.13199:1.72653:-0.24876;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213F:0.8684:0.88937:0.18591;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213L:0.82105:0.88937:0.01373;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213M:0.80793:0.88937:0.02308;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213N:0.54125:0.88937:-0.48608;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213S:0.77357:0.88937:-0.02555;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213T:0.83376:0.88937:-0.05294;MT-ND1:MT-ND3:5ldw:H:A:N126D:I213V:0.77716:0.88937:-0.05191;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213F:1.17922:1.31726:0.10641;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213L:1.28517:1.31726:0.03409;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213M:1.20834:1.31726:0.03281;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213N:1.04855:1.31726:-0.31828;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213S:1.2857:1.31726:-0.03982;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213T:1.31689:1.31726:-0.06167;MT-ND1:MT-ND3:5ldx:H:A:N126D:I213V:1.23381:1.31726:-0.01765;MT-ND1:NDUFS2:5lc5:H:D:N126D:A276E:0.09104:0.07203:-0.00958;MT-ND1:NDUFS2:5lc5:H:D:N126D:A276G:0.54278:0.07203:0.45938;MT-ND1:NDUFS2:5lc5:H:D:N126D:A276P:0.5412:0.07203:0.4897;MT-ND1:NDUFS2:5lc5:H:D:N126D:A276S:0.32181:0.07203:0.22672;MT-ND1:NDUFS2:5lc5:H:D:N126D:A276T:-0.14281:0.07203:-0.30414;MT-ND1:NDUFS2:5lc5:H:D:N126D:A276V:-0.27458:0.07203:-0.40074;MT-ND1:NDUFS2:5ldw:H:D:N126D:A276E:0.5638429:0.1520945:0.4444985;MT-ND1:NDUFS2:5ldw:H:D:N126D:A276G:0.6218535:0.1520945:0.5169461;MT-ND1:NDUFS2:5ldw:H:D:N126D:A276P:0.5167226:0.1520945:0.1625805;MT-ND1:NDUFS2:5ldw:H:D:N126D:A276S:-0.22623992:0.1520945:-0.3965543;MT-ND1:NDUFS2:5ldw:H:D:N126D:A276T:-0.10765352:0.1520945:-0.2743957;MT-ND1:NDUFS2:5ldw:H:D:N126D:A276V:0.03588573:0.1520945:-0.0879116;MT-ND1:NDUFS2:5ldx:H:D:N126D:A276E:0.10071504:0.1839706:0.21912504;MT-ND1:NDUFS2:5ldx:H:D:N126D:A276G:0.289810411:0.1839706:0.1624912;MT-ND1:NDUFS2:5ldx:H:D:N126D:A276P:0.37550653:0.1839706:0.1954252;MT-ND1:NDUFS2:5ldx:H:D:N126D:A276S:0.4777763:0.1839706:0.2913374;MT-ND1:NDUFS2:5ldx:H:D:N126D:A276T:-0.479708229:0.1839706:-0.6121604;MT-ND1:NDUFS2:5ldx:H:D:N126D:A276V:-0.149022:0.1839706:-0.2327356 | 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MT-ND1:MT-ND3:5lc5:H:A:N126K:I213F:0.49754:0.39067:0.26227;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213L:0.50516:0.39067:0.02712;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213M:0.65707:0.39067:0.09873;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213N:-0.23573:0.39067:-0.64295;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213S:0.58293:0.39067:-0.01554;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213T:0.29141:0.39067:0.0437;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213V:0.16195:0.39067:-0.24876;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213F:0.0437:-0.13726:0.18591;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213L:-0.04437:-0.13726:0.01373;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213M:0.02401:-0.13726:0.02308;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213N:-0.27174:-0.13726:-0.48608;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213S:-0.13648:-0.13726:-0.02555;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213T:-0.12464:-0.13726:-0.05294;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213V:-0.03989:-0.13726:-0.05191;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213F:0.04482:0.22525:0.10641;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213L:0.38613:0.22525:0.03409;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213M:0.40779:0.22525:0.03281;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213N:0.10833:0.22525:-0.31828;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213S:0.31437:0.22525:-0.03982;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213T:0.37564:0.22525:-0.06167;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213V:0.35195:0.22525:-0.01765;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276E:-0.98124:-1.13044:-0.00958;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276G:-0.66335:-1.13044:0.45938;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276P:-0.47804:-1.13044:0.4897;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276S:-0.86646:-1.13044:0.22672;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276T:-1.36649:-1.13044:-0.30414;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276V:-1.55567:-1.13044:-0.40074;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276E:0.2681222:-0.189033:0.4444985;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276G:0.0695735:-0.189033:0.5169461;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276P:0.059423236:-0.189033:0.1625805;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276S:-0.6524438:-0.189033:-0.3965543;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276T:-0.5528349:-0.189033:-0.2743957;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276V:-0.17823476:-0.189033:-0.0879116;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276E:-0.31812917:-0.4004477:0.21912504;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276G:-0.19093913:-0.4004477:0.1624912;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276P:-0.29156192:-0.4004477:0.1954252;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276S:-0.11178995:-0.4004477:0.2913374;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276T:-0.890995874:-0.4004477:-0.6121604;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276V:-0.62977184:-0.4004477:-0.2327356 | MT-ND1:MT-ND3:5lc5:H:A:N126K:I213F:0.49754:0.39067:0.26227;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213L:0.50516:0.39067:0.02712;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213M:0.65707:0.39067:0.09873;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213N:-0.23573:0.39067:-0.64295;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213S:0.58293:0.39067:-0.01554;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213T:0.29141:0.39067:0.0437;MT-ND1:MT-ND3:5lc5:H:A:N126K:I213V:0.16195:0.39067:-0.24876;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213F:0.0437:-0.13726:0.18591;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213L:-0.04437:-0.13726:0.01373;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213M:0.02401:-0.13726:0.02308;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213N:-0.27174:-0.13726:-0.48608;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213S:-0.13648:-0.13726:-0.02555;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213T:-0.12464:-0.13726:-0.05294;MT-ND1:MT-ND3:5ldw:H:A:N126K:I213V:-0.03989:-0.13726:-0.05191;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213F:0.04482:0.22525:0.10641;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213L:0.38613:0.22525:0.03409;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213M:0.40779:0.22525:0.03281;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213N:0.10833:0.22525:-0.31828;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213S:0.31437:0.22525:-0.03982;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213T:0.37564:0.22525:-0.06167;MT-ND1:MT-ND3:5ldx:H:A:N126K:I213V:0.35195:0.22525:-0.01765;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276E:-0.98124:-1.13044:-0.00958;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276G:-0.66335:-1.13044:0.45938;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276P:-0.47804:-1.13044:0.4897;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276S:-0.86646:-1.13044:0.22672;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276T:-1.36649:-1.13044:-0.30414;MT-ND1:NDUFS2:5lc5:H:D:N126K:A276V:-1.55567:-1.13044:-0.40074;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276E:0.2681222:-0.189033:0.4444985;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276G:0.0695735:-0.189033:0.5169461;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276P:0.059423236:-0.189033:0.1625805;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276S:-0.6524438:-0.189033:-0.3965543;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276T:-0.5528349:-0.189033:-0.2743957;MT-ND1:NDUFS2:5ldw:H:D:N126K:A276V:-0.17823476:-0.189033:-0.0879116;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276E:-0.31812917:-0.4004477:0.21912504;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276G:-0.19093913:-0.4004477:0.1624912;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276P:-0.29156192:-0.4004477:0.1954252;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276S:-0.11178995:-0.4004477:0.2913374;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276T:-0.890995874:-0.4004477:-0.6121604;MT-ND1:NDUFS2:5ldx:H:D:N126K:A276V:-0.62977184:-0.4004477:-0.2327356 |
| DDG inter | MT-ND1:MT-ND3:5lc5:H:A:N126D:D112G:2.08682:1.59534991:0.420539469;MT-ND1:MT-ND3:5lc5:H:A:N126D:D112V:2.24704:1.59534991:0.490299225;MT-ND1:MT-ND3:5lc5:H:A:N126D:D112Y:2.18813:1.59534991:0.46697998;MT-ND1:MT-ND3:5lc5:H:A:N126D:D112A:2.15633:1.59534991:0.367700577;MT-ND1:MT-ND3:5lc5:H:A:N126D:D112E:2.16361:1.59534991:0.438530743;MT-ND1:MT-ND3:5lc5:H:A:N126D:D112N:1.47393:1.59534991:-0.230379492;MT-ND1:MT-ND3:5lc5:H:A:N126D:D112H:2.01873:1.59534991:0.331509769;MT-ND1:MT-ND3:5lc5:H:A:N126D:S45A:1.74469:1.59534991:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:N126D:S45P:1.60729:1.59534991:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:N126D:S45Y:1.83253:1.59534991:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:N126D:S45F:1.72617:1.59534991:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:N126D:S45T:1.67779:1.59534991:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:N126D:S45C:1.69902:1.59534991:-0.407060623;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112G:1.42733:0.906030297:0.59258002;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112V:1.56163:0.906030297:0.666999817;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112Y:1.90999:0.906030297:0.731909573;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112A:1.36149:0.906030297:0.565000534;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112E:0.96178:0.906030297:-0.0375785828;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112N:0.70837:0.906030297:-0.179788589;MT-ND1:MT-ND3:5ldw:H:A:N126D:D112H:0.84452:0.906030297:-0.104170226;MT-ND1:MT-ND3:5ldw:H:A:N126D:P46S:1.00164:0.906030297:0.256430447;MT-ND1:MT-ND3:5ldw:H:A:N126D:P46R:0.33767:0.906030297:-0.374820709;MT-ND1:MT-ND3:5ldw:H:A:N126D:P46T:1.30631:0.906030297:0.476390839;MT-ND1:MT-ND3:5ldw:H:A:N126D:P46H:0.60851:0.906030297:-0.123018265;MT-ND1:MT-ND3:5ldw:H:A:N126D:P46L:0.35891:0.906030297:-0.427488327;MT-ND1:MT-ND3:5ldw:H:A:N126D:P46A:0.92305:0.906030297:0.124702454;MT-ND1:MT-ND3:5ldw:H:A:N126D:S45A:0.89838:0.906030297:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:N126D:S45P:0.96061:0.906030297:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:N126D:S45Y:1.47901:0.906030297:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:N126D:S45F:1.20761:0.906030297:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:N126D:S45T:0.92759:0.906030297:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:N126D:S45C:1.48361:0.906030297:-0.0661293045;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112G:1.61942:1.31459963:0.296100616;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112V:1.50579:1.31459963:0.213339239;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112Y:1.71124:1.31459963:0.368209064;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112A:1.49826:1.31459963:0.172319025;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112E:1.18987:1.31459963:-0.0294204708;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112N:1.67904:1.31459963:0.381619632;MT-ND1:MT-ND3:5ldx:H:A:N126D:D112H:1.6664:1.31459963:0.369738758;MT-ND1:MT-ND3:5ldx:H:A:N126D:P46S:1.32199:1.31459963:0.202388763;MT-ND1:MT-ND3:5ldx:H:A:N126D:P46R:0.33305:1.31459963:-0.366769791;MT-ND1:MT-ND3:5ldx:H:A:N126D:P46T:1.27012:1.31459963:0.200049967;MT-ND1:MT-ND3:5ldx:H:A:N126D:P46H:1.21756:1.31459963:-0.150340647;MT-ND1:MT-ND3:5ldx:H:A:N126D:P46L:1.48068:1.31459963:-0.57003057;MT-ND1:MT-ND3:5ldx:H:A:N126D:P46A:1.88825:1.31459963:0.17194137;MT-ND1:MT-ND3:5ldx:H:A:N126D:S45A:1.85508:1.31459963:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:N126D:S45P:1.80929:1.31459963:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:N126D:S45Y:1.83161:1.31459963:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:N126D:S45F:1.80101:1.31459963:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:N126D:S45T:1.42456:1.31459963:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:N126D:S45C:1.67161:1.31459963:0.429790109 | MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112G:1.11503:0.641970038:0.420539469;MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112A:0.97426:0.641970038:0.367700577;MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112N:0.55377:0.641970038:-0.230379492;MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112V:1.05508:0.641970038:0.490299225;MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112E:1.223:0.641970038:0.438530743;MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112H:1.14002:0.641970038:0.331509769;MT-ND1:MT-ND3:5lc5:H:A:N126Y:D112Y:1.28409:0.641970038:0.46697998;MT-ND1:MT-ND3:5lc5:H:A:N126Y:S45C:0.28527:0.641970038:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:N126Y:S45A:0.5488:0.641970038:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:N126Y:S45P:0.03113:0.641970038:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:N126Y:S45F:0.74714:0.641970038:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:N126Y:S45T:0.44212:0.641970038:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:N126Y:S45Y:0.54682:0.641970038:-0.209069446;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112G:0.88171:0.15291062:0.59258002;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112A:0.59509:0.15291062:0.565000534;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112N:-0.06703:0.15291062:-0.179788589;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112V:0.75317:0.15291062:0.666999817;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112E:0.10308:0.15291062:-0.0375785828;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112H:0.07519:0.15291062:-0.104170226;MT-ND1:MT-ND3:5ldw:H:A:N126Y:D112Y:0.90913:0.15291062:0.731909573;MT-ND1:MT-ND3:5ldw:H:A:N126Y:P46T:0.55525:0.15291062:0.476390839;MT-ND1:MT-ND3:5ldw:H:A:N126Y:P46S:0.30865:0.15291062:0.256430447;MT-ND1:MT-ND3:5ldw:H:A:N126Y:P46R:-0.44743:0.15291062:-0.374820709;MT-ND1:MT-ND3:5ldw:H:A:N126Y:P46A:0.27612:0.15291062:0.124702454;MT-ND1:MT-ND3:5ldw:H:A:N126Y:P46L:-0.26041:0.15291062:-0.427488327;MT-ND1:MT-ND3:5ldw:H:A:N126Y:P46H:0.04818:0.15291062:-0.123018265;MT-ND1:MT-ND3:5ldw:H:A:N126Y:S45C:0.77761:0.15291062:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:N126Y:S45A:0.1214:0.15291062:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:N126Y:S45P:-0.18661:0.15291062:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:N126Y:S45F:0.15736:0.15291062:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:N126Y:S45T:0.28745:0.15291062:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:N126Y:S45Y:0.90877:0.15291062:0.377010345;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112G:0.77043:0.512129188:0.296100616;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112A:0.64577:0.512129188:0.172319025;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112N:0.81685:0.512129188:0.381619632;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112V:0.72397:0.512129188:0.213339239;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112E:0.39977:0.512129188:-0.0294204708;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112H:0.87536:0.512129188:0.369738758;MT-ND1:MT-ND3:5ldx:H:A:N126Y:D112Y:0.85221:0.512129188:0.368209064;MT-ND1:MT-ND3:5ldx:H:A:N126Y:P46T:0.56965:0.512129188:0.200049967;MT-ND1:MT-ND3:5ldx:H:A:N126Y:P46S:0.61604:0.512129188:0.202388763;MT-ND1:MT-ND3:5ldx:H:A:N126Y:P46R:-0.16481:0.512129188:-0.366769791;MT-ND1:MT-ND3:5ldx:H:A:N126Y:P46A:0.52745:0.512129188:0.17194137;MT-ND1:MT-ND3:5ldx:H:A:N126Y:P46L:-0.10107:0.512129188:-0.57003057;MT-ND1:MT-ND3:5ldx:H:A:N126Y:P46H:0.15374:0.512129188:-0.150340647;MT-ND1:MT-ND3:5ldx:H:A:N126Y:S45C:0.86517:0.512129188:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:N126Y:S45A:1.09013:0.512129188:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:N126Y:S45P:0.86675:0.512129188:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:N126Y:S45F:0.16075:0.512129188:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:N126Y:S45T:0.4601:0.512129188:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:N126Y:S45Y:0.57889:0.512129188:0.507420719 | 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