| Chr |
chrM |
chrM |
chrM |
chrM |
chrM |
chrM |
| Start |
3490 |
3490 |
3491 |
3491 |
3492 |
3492 |
| End |
3490 |
3490 |
3491 |
3491 |
3492 |
3492 |
| Ref |
A |
A |
A |
A |
A |
A |
| Alt |
G |
C |
C |
T |
T |
C |
| MitImpact id |
MI.11141 |
MI.11142 |
MI.11143 |
MI.11144 |
MI.11145 |
MI.11146 |
| Gene symbol |
MT-ND1 |
MT-ND1 |
MT-ND1 |
MT-ND1 |
MT-ND1 |
MT-ND1 |
| Respiratory Chain complex |
I |
I |
I |
I |
I |
I |
| Ensembl gene id |
ENSG00000198888 |
ENSG00000198888 |
ENSG00000198888 |
ENSG00000198888 |
ENSG00000198888 |
ENSG00000198888 |
| Ensembl protein id |
ENSP00000354687 |
ENSP00000354687 |
ENSP00000354687 |
ENSP00000354687 |
ENSP00000354687 |
ENSP00000354687 |
| Ensembl transcript id |
ENST00000361390 |
ENST00000361390 |
ENST00000361390 |
ENST00000361390 |
ENST00000361390 |
ENST00000361390 |
| Uniprot name |
NU1M_HUMAN |
NU1M_HUMAN |
NU1M_HUMAN |
NU1M_HUMAN |
NU1M_HUMAN |
NU1M_HUMAN |
| Uniprot id |
P03886 |
P03886 |
P03886 |
P03886 |
P03886 |
P03886 |
| Ncbi gene id |
4535 |
4535 |
4535 |
4535 |
4535 |
4535 |
| Ncbi protein id |
YP_003024026.1 |
YP_003024026.1 |
YP_003024026.1 |
YP_003024026.1 |
YP_003024026.1 |
YP_003024026.1 |
| Gene position |
184 |
184 |
185 |
185 |
186 |
186 |
| AA position |
62 |
62 |
62 |
62 |
62 |
62 |
| AA ref |
K |
K |
K |
K |
K |
K |
| AA alt |
E |
Q |
T |
M |
N |
N |
| Codon substitution |
Aaa/Gaa |
Aaa/Caa |
aAa/aCa |
aAa/aTa |
aaA/aaT |
aaA/aaC |
| PhyloP 100V |
0.451339 |
0.451339 |
0.218937 |
0.218937 |
-5.8235 |
-5.8235 |
| PhastCons 100V |
0 |
0 |
0 |
0 |
0 |
0 |
| PolyPhen2 |
benign |
benign |
benign |
possibly_damaging |
benign |
benign |
| PolyPhen2 score |
0.18 |
0.02 |
0.41 |
0.58 |
0.26 |
0.26 |
| SIFT |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| SIFT score |
1.0 |
0.59 |
0.59 |
0.12 |
0.51 |
0.51 |
| SIFT4G |
Damaging |
Tolerated |
Damaging |
Damaging |
Damaging |
Damaging |
| SIFT4G score |
0.009 |
0.11 |
0.001 |
0 |
0.001 |
0.001 |
| FatHmm |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| FatHmm score |
-0.79 |
-0.67 |
1.17 |
-0.08 |
-1.09 |
-1.09 |
| FatHmmW |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| FatHmmW score |
2.77 |
2.76 |
2.81 |
2.74 |
2.75 |
2.75 |
| PROVEAN |
neutral |
neutral |
deleterious |
neutral |
neutral |
neutral |
| PROVEAN score |
-1.36 |
-0.29 |
-2.5 |
-2.33 |
-1.59 |
-1.59 |
| MutationAssessor |
medium impact |
low impact |
neutral impact |
low impact |
low impact |
low impact |
| MutationAssessor score |
1.95 |
1.32 |
0.55 |
1.05 |
1.29 |
1.29 |
| EFIN SP |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| EFIN SP score |
0.84 |
0.82 |
0.69 |
0.71 |
0.68 |
0.68 |
| EFIN HD |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| EFIN HD score |
0.7 |
0.97 |
0.66 |
0.61 |
0.67 |
0.67 |
| CADD |
deleterious |
deleterious |
deleterious |
deleterious |
deleterious |
deleterious |
| CADD score |
3.92 |
2.2 |
3.51 |
3.74 |
3.82 |
3.75 |
| CADD phred |
23.5 |
17.49 |
23.1 |
23.3 |
23.4 |
23.3 |
| VEST pvalue |
0.26 |
0.39 |
0.14 |
0.12 |
0.5 |
0.5 |
| VEST FDR |
0.45 |
0.5 |
0.4 |
0.4 |
0.6 |
0.6 |
| PANTHER |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| PANTHER score |
0.24 |
0.27 |
0.16 |
0.3 |
0.3 |
0.3 |
| PhD-SNP |
disease |
neutral |
neutral |
neutral |
disease |
disease |
| PhD-SNP score |
0.64 |
0.33 |
0.37 |
0.45 |
0.52 |
0.52 |
| SNAP |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| SNAP score |
0.43 |
0.25 |
0.38 |
0.28 |
0.28 |
0.28 |
| Meta-SNP |
disease |
neutral |
neutral |
neutral |
disease |
disease |
| Meta-SNP score |
0.5 |
0.44 |
0.43 |
0.49 |
0.5 |
0.5 |
| Meta-SNP RI |
0 |
1 |
1 |
0 |
0 |
0 |
| CAROL |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| CAROL score |
0.18 |
0.38 |
0.37 |
0.88 |
0.39 |
0.39 |
| Condel |
deleterious |
deleterious |
deleterious |
neutral |
deleterious |
deleterious |
| Condel score |
0.91 |
0.79 |
0.59 |
0.27 |
0.63 |
0.63 |
| COVEC WMV |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| COVEC WMV score |
-3 |
-6 |
-6 |
-3 |
-6 |
-6 |
| MtoolBox |
neutral |
neutral |
neutral |
deleterious |
neutral |
neutral |
| MtoolBox DS |
0.27 |
0.16 |
0.37 |
0.5 |
0.38 |
0.38 |
| PolyPhen2 transf |
medium impact |
medium impact |
medium impact |
medium impact |
medium impact |
medium impact |
| PolyPhen2 transf score |
-0.13 |
0.84 |
-0.6 |
-0.88 |
-0.32 |
-0.32 |
| SIFT_transf |
high impact |
medium impact |
medium impact |
medium impact |
medium impact |
medium impact |
| SIFT transf score |
1.96 |
0.36 |
0.36 |
-0.21 |
0.29 |
0.29 |
| MutationAssessor transf |
medium impact |
medium impact |
medium impact |
medium impact |
medium impact |
medium impact |
| MutationAssessor transf score |
0.52 |
-0.04 |
-0.71 |
-0.27 |
-0.06 |
-0.06 |
| CHASM pvalue |
0.42 |
0.36 |
0.2 |
0.19 |
0.34 |
0.34 |
| CHASM FDR |
0.8 |
0.8 |
0.8 |
0.8 |
0.8 |
0.8 |
| APOGEE1 |
Neutral |
Neutral |
Neutral |
Neutral |
Neutral |
Neutral |
| APOGEE1 score |
0.25 |
0.36 |
0.3 |
0.41 |
0.38 |
0.38 |
| APOGEE2 |
Likely-benign |
Likely-benign |
Likely-benign |
VUS- |
Likely-benign |
Likely-benign |
| APOGEE2 score |
0.120080038285879 |
0.153817425150168 |
0.250683507845739 |
0.284336980000649 |
0.185893546384039 |
0.185893546384039 |
| SNPDryad score |
0.74 |
0.59 |
0.75 |
0.78 |
0.59 |
0.59 |
| MutationTaster |
polymorphism |
polymorphism |
polymorphism |
polymorphism |
polymorphism |
polymorphism |
| MutationTaster score |
1 |
1 |
1 |
1 |
1 |
1 |
| DEOGEN2 score |
0.02 |
0.01 |
0.07 |
0.07 |
0.02 |
0.02 |
| Mitoclass.1 |
neutral |
neutral |
neutral |
neutral |
neutral |
neutral |
| dbSNP 155 id |
. |
. |
. |
. |
. |
rs878950749 |
| ClinVar July2022 Variation id |
. |
. |
. |
. |
. |
. |
| ClinVar July2022 CLNSIG |
. |
. |
. |
. |
. |
. |
| ClinVar July2022 CLNDN |
. |
. |
. |
. |
. |
. |
| ClinVar July2022 CLNDISDB |
. |
. |
. |
. |
. |
. |
| COSMIC 90 |
. |
. |
. |
. |
. |
. |
| MITOMAP Allele |
. |
. |
. |
. |
. |
. |
| MITOMAP Disease Het/Hom |
. |
. |
. |
. |
. |
. |
| MITOMAP Disease Clinical info |
. |
. |
. |
. |
. |
. |
| MITOMAP Disease Status |
. |
. |
. |
. |
. |
. |
| MITOMAP Disease GenBank Freq |
. |
. |
. |
. |
. |
. |
| MITOMAP Disease GenBank Seqs |
. |
. |
. |
. |
. |
. |
| MITOMAP Disease GenBank Curated refs |
. |
. |
. |
. |
. |
. |
| MITOMAP General GenBank Freq |
. |
. |
. |
. |
. |
0.00002 |
| MITOMAP General GenBank Seqs |
. |
. |
. |
. |
. |
1 |
| MITOMAP General Curated refs |
. |
. |
. |
. |
. |
1 |
| gnomAD 3.1 filter |
. |
. |
. |
. |
. |
npg |
| gnomAD 3.1 AC Homo |
. |
. |
. |
. |
. |
0 |
| gnomAD 3.1 AC Het |
. |
. |
. |
. |
. |
0 |
| gnomAD 3.1 AF Hom |
. |
. |
. |
. |
. |
0 |
| gnomAD 3.1 AF Het |
. |
. |
. |
. |
. |
0 |
| gnomAD 3.1 AN |
. |
. |
. |
. |
. |
56222 |
| HelixMTdb AC Hom |
. |
. |
. |
. |
. |
. |
| HelixMTdb AF Hom |
. |
. |
. |
. |
. |
. |
| HelixMTdb AC Het |
. |
. |
. |
. |
. |
. |
| HelixMTdb AF Het |
. |
. |
. |
. |
. |
. |
| HelixMTdb mean ARF |
. |
. |
. |
. |
. |
. |
HelixMTdb max ARF |
. |
. |
. |
. |
. |
. |
| EVmutation |
MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
MT-ND1_62K|72I:0.189929;66S:0.140557;68I:0.127828;63P:0.110243;216A:0.080946;89L:0.077279;71Y:0.073689;217A:0.072198;158G:0.067654;246T:0.06375;69T:0.063669 |
| Site A InterP |
ND1_62 |
ND1_62 |
ND1_62 |
ND1_62 |
ND1_62 |
ND1_62 |
| Site B InterP |
ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
ND2_321;ND4L_92;ND6_131;ND2_6;ND3_49;ND3_45;ND3_18;ND3_79;ND3_92;ND3_91;ND3_85;ND4_163;ND4L_80;ND4L_58;ND4L_48;ND5_41;ND5_420;ND5_503;ND5_509;ND6_120;ND6_139;ND6_7 |
| Covariation Score InterP |
mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
mfDCA_26.65;mfDCA_32.46;mfDCA_33.28;cMI_49.81888;cMI_36.38655;cMI_34.76365;cMI_34.45007;cMI_33.97552;cMI_33.01791;cMI_32.12901;cMI_31.90963;cMI_24.8798;cMI_54.94898;cMI_49.44061;cMI_49.30168;cMI_31.77544;cMI_30.59127;cMI_29.55244;cMI_29.13742;cMI_49.49418;cMI_47.67927;cMI_47.14359 |
| Site A IntraP |
ND1_62 |
ND1_62 |
ND1_62 |
ND1_62 |
ND1_62 |
ND1_62 |
| Site B IntraP |
ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
ND1_161;ND1_23;ND1_87;ND1_153;ND1_2;ND1_85;ND1_269;ND1_84;ND1_93;ND1_67;ND1_81;ND1_258;ND1_71;ND1_249 |
| Covariation Score IntraP |
cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
cMI_19.377666;cMI_16.296112;cMI_15.746119;cMI_15.655493;cMI_15.331367;cMI_15.294185;cMI_15.04784;cMI_14.834477;cMI_14.592816;cMI_14.04824;cMI_13.877844;cMI_13.72355;cMI_13.419802;cMI_13.405388 |
| CPD AA ref |
. |
. |
. |
. |
. |
. |
| CPD AA alt |
. |
. |
. |
. |
. |
. |
| CPD Aln pos |
. |
. |
. |
. |
. |
. |
| CPD Frequency |
. |
. |
. |
. |
. |
. |
| CPD Species name |
. |
. |
. |
. |
. |
. |
| CPD RefSeq Protein ID |
. |
. |
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| CPD Ncbi Taxon id |
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| DDG intra |
MT-ND1:K62E:A249S:1.04071:0.581859:0.416877;MT-ND1:K62E:A249P:-0.397685:0.581859:-0.969457;MT-ND1:K62E:A249V:0.99437:0.581859:0.387706;MT-ND1:K62E:A249G:0.847108:0.581859:0.24999;MT-ND1:K62E:A249E:0.585371:0.581859:-0.081467;MT-ND1:K62E:A249T:1.1826:0.581859:0.585672;MT-ND1:K62E:N93T:0.732472:0.581859:0.161189;MT-ND1:K62E:N93H:0.18544:0.581859:-0.430894;MT-ND1:K62E:N93K:-0.0759206:0.581859:-0.753586;MT-ND1:K62E:N93I:0.103405:0.581859:-0.528503;MT-ND1:K62E:N93Y:-0.445122:0.581859:-1.03778;MT-ND1:K62E:N93S:0.668844:0.581859:0.0416942;MT-ND1:K62E:N93D:0.824512:0.581859:0.206064;MT-ND1:K62E:P2R:1.25558:0.581859:0.63914;MT-ND1:K62E:P2T:0.79863:0.581859:0.178692;MT-ND1:K62E:P2H:1.50412:0.581859:0.926272;MT-ND1:K62E:P2L:0.757612:0.581859:0.109703;MT-ND1:K62E:P2A:1.06867:0.581859:0.449523;MT-ND1:K62E:P2S:0.676861:0.581859:0.119094 |
MT-ND1:K62Q:A249G:0.776656:0.490174:0.24999;MT-ND1:K62Q:A249E:0.44095:0.490174:-0.081467;MT-ND1:K62Q:A249P:-0.510834:0.490174:-0.969457;MT-ND1:K62Q:A249V:0.839957:0.490174:0.387706;MT-ND1:K62Q:A249T:1.09273:0.490174:0.585672;MT-ND1:K62Q:N93D:0.669307:0.490174:0.206064;MT-ND1:K62Q:N93Y:-0.546119:0.490174:-1.03778;MT-ND1:K62Q:N93S:0.561219:0.490174:0.0416942;MT-ND1:K62Q:N93H:0.0321485:0.490174:-0.430894;MT-ND1:K62Q:N93T:0.648411:0.490174:0.161189;MT-ND1:K62Q:N93I:-0.0709373:0.490174:-0.528503;MT-ND1:K62Q:A249S:0.907528:0.490174:0.416877;MT-ND1:K62Q:N93K:-0.238147:0.490174:-0.753586;MT-ND1:K62Q:P2L:0.550066:0.490174:0.109703;MT-ND1:K62Q:P2T:0.666497:0.490174:0.178692;MT-ND1:K62Q:P2A:0.932338:0.490174:0.449523;MT-ND1:K62Q:P2S:0.605205:0.490174:0.119094;MT-ND1:K62Q:P2H:1.37583:0.490174:0.926272;MT-ND1:K62Q:P2R:1.19271:0.490174:0.63914 |
MT-ND1:K62T:A249S:1.17339:0.677214:0.416877;MT-ND1:K62T:A249T:1.35942:0.677214:0.585672;MT-ND1:K62T:A249V:1.17436:0.677214:0.387706;MT-ND1:K62T:A249P:-0.19227:0.677214:-0.969457;MT-ND1:K62T:A249E:0.779932:0.677214:-0.081467;MT-ND1:K62T:A249G:0.961282:0.677214:0.24999;MT-ND1:K62T:N93I:0.26794:0.677214:-0.528503;MT-ND1:K62T:N93T:0.832255:0.677214:0.161189;MT-ND1:K62T:N93S:0.765149:0.677214:0.0416942;MT-ND1:K62T:N93K:0.0471628:0.677214:-0.753586;MT-ND1:K62T:N93D:0.960075:0.677214:0.206064;MT-ND1:K62T:N93H:0.453655:0.677214:-0.430894;MT-ND1:K62T:N93Y:-0.237635:0.677214:-1.03778;MT-ND1:K62T:P2H:1.65574:0.677214:0.926272;MT-ND1:K62T:P2A:1.19454:0.677214:0.449523;MT-ND1:K62T:P2T:0.992374:0.677214:0.178692;MT-ND1:K62T:P2R:1.47925:0.677214:0.63914;MT-ND1:K62T:P2S:0.803022:0.677214:0.119094;MT-ND1:K62T:P2L:0.628657:0.677214:0.109703 |
MT-ND1:K62M:A249G:-0.871784:-1.08529:0.24999;MT-ND1:K62M:A249E:-1.00519:-1.08529:-0.081467;MT-ND1:K62M:A249S:-0.659035:-1.08529:0.416877;MT-ND1:K62M:A249P:-2.05651:-1.08529:-0.969457;MT-ND1:K62M:A249V:-0.682354:-1.08529:0.387706;MT-ND1:K62M:A249T:-0.493693:-1.08529:0.585672;MT-ND1:K62M:N93S:-1.05384:-1.08529:0.0416942;MT-ND1:K62M:N93D:-0.901726:-1.08529:0.206064;MT-ND1:K62M:N93Y:-2.12038:-1.08529:-1.03778;MT-ND1:K62M:N93H:-1.48116:-1.08529:-0.430894;MT-ND1:K62M:N93K:-1.80338:-1.08529:-0.753586;MT-ND1:K62M:N93I:-1.62462:-1.08529:-0.528503;MT-ND1:K62M:N93T:-0.884002:-1.08529:0.161189;MT-ND1:K62M:P2S:-0.930917:-1.08529:0.119094;MT-ND1:K62M:P2A:-0.641795:-1.08529:0.449523;MT-ND1:K62M:P2L:-1.02882:-1.08529:0.109703;MT-ND1:K62M:P2H:-0.203589:-1.08529:0.926272;MT-ND1:K62M:P2T:-0.806913:-1.08529:0.178692;MT-ND1:K62M:P2R:-0.413394:-1.08529:0.63914 |
MT-ND1:K62N:A249S:1.13755:0.851927:0.416877;MT-ND1:K62N:A249E:0.842145:0.851927:-0.081467;MT-ND1:K62N:A249V:1.18013:0.851927:0.387706;MT-ND1:K62N:A249G:0.800294:0.851927:0.24999;MT-ND1:K62N:A249T:1.40202:0.851927:0.585672;MT-ND1:K62N:A249P:-0.0113826:0.851927:-0.969457;MT-ND1:K62N:N93Y:-0.243065:0.851927:-1.03778;MT-ND1:K62N:N93D:1.1439:0.851927:0.206064;MT-ND1:K62N:N93H:0.251854:0.851927:-0.430894;MT-ND1:K62N:N93K:0.122694:0.851927:-0.753586;MT-ND1:K62N:N93S:0.928952:0.851927:0.0416942;MT-ND1:K62N:N93I:0.0884897:0.851927:-0.528503;MT-ND1:K62N:N93T:1.01233:0.851927:0.161189;MT-ND1:K62N:P2A:1.27791:0.851927:0.449523;MT-ND1:K62N:P2S:0.939521:0.851927:0.119094;MT-ND1:K62N:P2L:0.733007:0.851927:0.109703;MT-ND1:K62N:P2T:1.11195:0.851927:0.178692;MT-ND1:K62N:P2R:1.50251:0.851927:0.63914;MT-ND1:K62N:P2H:1.68274:0.851927:0.926272 |
MT-ND1:K62N:A249S:1.13755:0.851927:0.416877;MT-ND1:K62N:A249E:0.842145:0.851927:-0.081467;MT-ND1:K62N:A249V:1.18013:0.851927:0.387706;MT-ND1:K62N:A249G:0.800294:0.851927:0.24999;MT-ND1:K62N:A249T:1.40202:0.851927:0.585672;MT-ND1:K62N:A249P:-0.0113826:0.851927:-0.969457;MT-ND1:K62N:N93Y:-0.243065:0.851927:-1.03778;MT-ND1:K62N:N93D:1.1439:0.851927:0.206064;MT-ND1:K62N:N93H:0.251854:0.851927:-0.430894;MT-ND1:K62N:N93K:0.122694:0.851927:-0.753586;MT-ND1:K62N:N93S:0.928952:0.851927:0.0416942;MT-ND1:K62N:N93I:0.0884897:0.851927:-0.528503;MT-ND1:K62N:N93T:1.01233:0.851927:0.161189;MT-ND1:K62N:P2A:1.27791:0.851927:0.449523;MT-ND1:K62N:P2S:0.939521:0.851927:0.119094;MT-ND1:K62N:P2L:0.733007:0.851927:0.109703;MT-ND1:K62N:P2T:1.11195:0.851927:0.178692;MT-ND1:K62N:P2R:1.50251:0.851927:0.63914;MT-ND1:K62N:P2H:1.68274:0.851927:0.926272 |
| DDG intra interface |
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| DDG inter |
MT-ND1:MT-ND3:5lc5:H:A:K62E:L79P:3.60749:0.412649542:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79Q:2.87511:0.412649542:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79R:4.30188:0.412649542:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79V:2.28026:0.412649542:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62E:L79M:0.09989:0.412649542:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45F:0.35208:0.412649542:-0.184449762;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45A:0.6052:0.412649542:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45C:0.17853:0.412649542:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45P:-0.63057:0.412649542:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45T:0.10504:0.412649542:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62E:S45Y:0.51928:0.412649542:-0.209069446;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79P:4.50268:0.301341236:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79Q:2.36948:0.301341236:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79R:5.50838:0.301341236:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79V:1.39489:0.301341236:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62E:L79M:-0.37051:0.301341236:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45F:0.36466:0.301341236:0.122009657;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45A:0.47682:0.301341236:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45C:0.01122:0.301341236:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45P:0.03594:0.301341236:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45T:0.55431:0.301341236:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62E:S45Y:0.95424:0.301341236:0.377010345;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79P:4.743:0.575948715:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79Q:2.45156:0.575948715:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79R:5.67142:0.575948715:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79V:1.63669:0.575948715:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62E:L79M:-0.06359:0.575948715:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45F:1.10355:0.575948715:0.507999063;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45A:1.20875:0.575948715:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45C:1.04964:0.575948715:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45P:1.13652:0.575948715:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45T:0.90794:0.575948715:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62E:S45Y:1.06902:0.575948715:0.507420719 |
MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79V:1.62769:-0.241339117:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79M:-0.76247:-0.241339117:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79Q:2.23228:-0.241339117:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79R:4.12982:-0.241339117:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62Q:L79P:3.41535:-0.241339117:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45P:-1.35861:-0.241339117:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45A:-0.4992:-0.241339117:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45Y:-0.52016:-0.241339117:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45C:-0.63482:-0.241339117:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45T:-0.06226:-0.241339117:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62Q:S45F:-0.52595:-0.241339117:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79V:1.27141:-0.0290084835:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79M:-0.78372:-0.0290084835:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79Q:2.05022:-0.0290084835:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79R:5.26848:-0.0290084835:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62Q:L79P:3.94707:-0.0290084835:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45P:-0.30247:-0.0290084835:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45A:-0.03384:-0.0290084835:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45Y:0.34942:-0.0290084835:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45C:-0.31279:-0.0290084835:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45T:0.1782:-0.0290084835:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62Q:S45F:-0.08954:-0.0290084835:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79V:1.22648:0.0151092531:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79M:-0.52285:0.0151092531:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79Q:1.86838:0.0151092531:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79R:4.79778:0.0151092531:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62Q:L79P:4.04125:0.0151092531:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45P:0.70032:0.0151092531:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45A:0.53665:0.0151092531:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45Y:0.52526:0.0151092531:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45C:0.51468:0.0151092531:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45T:0.27175:0.0151092531:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62Q:S45F:0.54544:0.0151092531:0.507999063 |
MT-ND1:MT-ND3:5lc5:H:A:K62T:L79V:2.6662:0.832580209:1.93022037;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79R:4.85777:0.832580209:4.04436064;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79M:0.3109:0.832580209:-0.440640628;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79P:4.3808:0.832580209:3.76418948;MT-ND1:MT-ND3:5lc5:H:A:K62T:L79Q:3.27382:0.832580209:2.55721045;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45P:-0.34137:0.832580209:-1.09178007;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45Y:0.54121:0.832580209:-0.209069446;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45C:0.2024:0.832580209:-0.407060623;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45A:0.65075:0.832580209:-0.0903697982;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45T:0.92303:0.832580209:0.215980917;MT-ND1:MT-ND3:5lc5:H:A:K62T:S45F:0.4885:0.832580209:-0.184449762;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79V:1.36653:0.183251187:1.33322978;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79R:5.42788:0.183251187:5.28492975;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79M:-0.51625:0.183251187:-0.731390357;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79P:4.04873:0.183251187:3.95701027;MT-ND1:MT-ND3:5ldw:H:A:K62T:L79Q:2.32473:0.183251187:2.17544985;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45P:-0.15744:0.183251187:-0.288380057;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45Y:0.36945:0.183251187:0.377010345;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45C:-0.11214:0.183251187:-0.0661293045;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45A:0.0492:0.183251187:-0.0156085966;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45T:0.1089:0.183251187:0.170780182;MT-ND1:MT-ND3:5ldw:H:A:K62T:S45F:0.56165:0.183251187:0.122009657;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79V:1.33255:0.109650038:1.23217046;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79R:4.66289:0.109650038:4.86520052;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79M:-0.50269:0.109650038:-0.587769687;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79P:4.13879:0.109650038:4.08582926;MT-ND1:MT-ND3:5ldx:H:A:K62T:L79Q:1.99682:0.109650038:1.85684049;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45P:0.63491:0.109650038:0.854759216;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45Y:0.59073:0.109650038:0.507420719;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45C:0.53656:0.109650038:0.429790109;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45A:0.59559:0.109650038:0.531179786;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45T:0.66071:0.109650038:0.424250036;MT-ND1:MT-ND3:5ldx:H:A:K62T:S45F:0.42017:0.109650038:0.507999063 |
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